New dressing may keep amputation wounds clean and closed
NCT ID NCT03773575
First seen Jan 27, 2026 · Last updated Jun 23, 2026 · Updated 21 times
Summary
This study tested a vacuum dressing called PREVENA on 272 adults who had a leg amputated. The dressing applies gentle suction over the surgical cut to help it heal and prevent complications like infection, reopening, or fluid buildup. The goal was to see if this device reduces wound problems and medical costs compared to standard bandages.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Gemelli Hospital
Roma, RM, 8, 00168, Italy
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Thomas Jefferson University/Hospital
Philadelphia, Pennsylvania, 19107, United States
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Westchester Medical Center
Valhalla, New York, 10595, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
PREVENA™ PEEL & PLACE™ Dressing Kit (a vacuum dressing device)
What this could lead to
If it works, this could reduce wound complications like infection or reopening after leg amputation, potentially lowering hospital stays and repeat surgeries.
What could go wrong
This is a completed trial, but results may not apply to all patients or settings. The dressing is a device, not a drug, so benefits may be modest and depend on proper use.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.