New surgery could give amputees 'Bionic' control over prosthetic legs
NCT ID NCT03374319
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new way to perform leg amputations that connects muscles in the residual limb to act as biological motors. The goal is to allow people to control advanced prosthetic legs more naturally and with better feeling. Fifty adults needing a leg amputation due to injury, birth defects, or arthritis took part. The approach aims to improve how well the remaining muscles can be activated and sensed.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Modified amputation procedure (agonist-antagonist myoneural interface)
What this could lead to
If successful, this could lead to a standard surgical technique that gives people with leg amputations better control and feeling in their prosthetic limbs.
What could go wrong
This is a small, early-stage study with only 50 participants, so results may not apply to everyone. There are also risks like infection, poor wound healing, or the need for additional surgeries.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Brigham & Women's Hospital
Boston, Massachusetts, 02114, United States
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Massachusetts Institute of Technology Media Lab
Cambridge, Massachusetts, 02139, United States