Temporomandibular joint disorder

This study tests whether adding the drug sodium valproate to a standard jaw-washing procedure can lower inflammation in people with a painful jaw joint condition. Ten female participants with jaw clicking and pain will receive the drug intravenously during the procedure. Research…

This study tests whether custom-made surgical guides can help surgeons safely and accurately treat children with a stiff or fused jaw joint (TMJ ankylosis). The approach uses a special saw to cut the bone precisely. Eight children under 15 are taking part, and the study checks ho…

This study tests whether a jaw motion analyzer (JMA) can accurately diagnose temporomandibular disorders (TMDs) in 29 adults with chronic orofacial pain. Participants will have their jaw movements measured with the JMA and then compared to standard clinical exams and MRI results.…

This study compares lifestyle counseling alone versus lifestyle counseling combined with clinical Pilates in 62 women with temporomandibular disorders (TMD). Participants will be randomly assigned to one of two groups for 8 weeks. Researchers will measure pain, jaw function, post…

This study tests whether two devices, used one after the other, can reduce pain and disability from temporomandibular joint (TMJ) disorders. Adults aged 22 and older with TMJ pain will receive four treatment sessions and be followed for three months. Researchers will measure chan…

This study aimed to compare different treatments—like mouthguards, jaw exercises, and anti-inflammatory drugs—for jaw muscle or joint pain in children aged 7 to 14. The goal was to see which works best and if any affect jaw growth. However, the study was withdrawn before enrollin…

This study tests whether 3D-printed dental splints work better than traditional lab-made ones for people with jaw pain from temporomandibular disorders (TMD). About 120 adults aged 18-40 with TMD will be randomly assigned to get either a digital or conventional splint. Researcher…

This study compares two behavioral treatments for temporomandibular joint disorders (TMD), a common cause of jaw and face pain. 160 adults with long-term jaw pain will receive either standard dental care plus a highly individualized coping skills program, or standard care plus co…

This study tests whether wearing a custom mouth splint and getting a granisetron injection into the jaw muscle reduces pain from temporomandibular disorders (TMD) better than the splint alone or with lidocaine. About 48 adults with jaw muscle pain will be followed for 6 months. T…

This study explores whether immersive virtual reality can help reduce chronic pain in people with temporomandibular disorder (TMD). About 259 participants will experience active VR, a sham VR, or no VR while their pain tolerance is measured. The goal is to understand how VR works…

This study tests whether a brief education and self-management program with home exercises can reduce pain and improve daily function in adults with long-lasting jaw pain (TMD) as effectively as more intensive hands-on physiotherapy. Forty adults aged 18–65 with jaw pain for at l…

This study looks back at 65 adults who had one of two surgeries for a painful jaw joint condition (TMJ disc displacement). The goal is to see which surgery better improves mouth opening, reduces pain, and helps the jaw work better. Researchers also check recovery speed, side effe…

This study tests a computer-guided needle technique combined with a platelet-rich plasma (PRP) injection for people with a painful jaw joint condition called temporomandibular disorder (TMD). The goal is to see if the computer-guided method improves jaw function and reduces pain …

This study tests whether a web-based relaxation program can ease jaw pain from temporomandibular disorders (TMD). 124 patients will either use the app or get a standard mouth splint. Researchers will track pain, sleep, and stress over one year to see if the app is a helpful, low-…

This study looked at whether having more frequent contact with a clinician (at least once a week) improves satisfaction for people with long-lasting musculoskeletal conditions. Participants were split into two groups: one with standard contact and one with extra check-ins via tex…

This study tests whether a Norwegian clinic (NSAC) helps people with common mental health issues or muscle pain return to work sooner. 2500 adults are split into three groups: one gets treatment quickly, one waits 10-14 weeks, and one gets a basic check-up. Researchers will track…

This study is tracking 120 people who received a HYPE SCS hip stem during total hip replacement. Researchers will monitor how long the implant lasts, how satisfied patients are, and any complications over 5 years. The goal is to confirm the device is safe and works as intended in…

This study looks at tiny particles called exosomes, taken from a patient's own platelet-rich plasma, to see if they might help repair jaw joints. Researchers will compare these exosomes with other blood products in lab tests on cells. The goal is to understand their content and p…

This study compares 120 adults with primary headaches (migraine or tension-type) to healthy individuals. Researchers will measure tenderness in head and neck muscles and general pain sensitivity elsewhere in the body. The goal is to understand how these factors relate to headache…

This study looks at how jaw surgery changes not just your bite and appearance, but also your emotions, jaw muscles, and joint health. Researchers will follow 100 patients before and after surgery, using scans, muscle tests, and questionnaires to track these changes. The goal is t…

This study is investigating whether bruxism (teeth grinding or clenching) is associated with pelvic pain, erectile dysfunction, and anxiety in young men aged 18-30. Researchers will use questionnaires and physical exams to assess 100 participants. The goal is to better understand…

This study explores whether bruxism (teeth grinding or clenching) is related to pelvic floor dysfunction in young women aged 18-30. Researchers will use questionnaires and physical exams to assess jaw function, pelvic floor symptoms, and anxiety in 100 participants. The goal is t…

This study looks back at the medical records of about 4 million people who had physical or occupational therapy for muscle and joint problems. Researchers want to see if different ways of giving therapy lead to different results. No new treatments are tested—the goal is to learn …

This study examines the links between sleep bruxism (teeth grinding during sleep) and sleep quality, heart health, thyroid function, and mood. Researchers will give some participants opipramol, a drug that may reduce grinding activity, and monitor them with sleep tests. The goal …

This study aimed to see if a mobile monitoring tool could accurately identify surgical site infections (SSIs) in orthopedic surgery patients, compared to the usual manual review. The study was withdrawn before enrolling any participants, so no results are available. It was design…

This study looks at 50 adults with sleep bruxism (teeth grinding during sleep) to understand how it affects sleep, pain, anxiety, and overall health. Researchers will use sleep tests, blood samples, and questionnaires to find links between bruxism and other conditions. The goal i…

This study looks at how chronic jaw muscle pain relates to genetics, blood chemicals, and emotional state. Researchers will compare 102 adults with and without jaw pain to find connections. No treatment is given; the goal is to better understand the condition.

This study aimed to find out how many people with trigeminal neuralgia (a severe facial nerve pain condition) also have temporomandibular disorder (TMD), which causes jaw pain. Researchers planned to follow patients from three clinics and test a questionnaire to better diagnose b…