Could a common drug ease painful jaw clicking?
NCT ID NCT07487675
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding the drug sodium valproate to a standard jaw-washing procedure can lower inflammation in people with a painful jaw joint condition. Ten female participants with jaw clicking and pain will receive the drug intravenously during the procedure. Researchers will measure changes in an inflammatory protein called IL-6 to see if the combination works better than the procedure alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
sodium valproate
What this could lead to
If it works, this could point toward a new way to reduce inflammation and pain in jaw joint disorders.
What could go wrong
This is a very small early-phase trial with only 10 participants, so results may not apply widely. The drug's effect on inflammation is still uncertain.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tanta University
Tanta, Gharbia Governorate, 31773, Egypt