Spinal fracture
MONDO:0005309Traumatic or pathological injury to the spine in which the continuity of a vertebral bone is broken. Symptoms include back pain and difficulty bending and twisting.
Also known as: bone fracture of vertebral column, vertebral column bone fracture
138 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New titanium device shows promise for painful spine fractures
Disease control CompletedThis study tested a titanium implant called SPHEREPLAST in 37 people with spine fractures caused by osteoporosis or injury. The implant is placed during a procedure called balloon kyphoplasty to stabilize the broken bone and help it heal. Researchers looked at pain levels, disabi…
Sponsor: MT Ortho s.r.l. • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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Battlefield plasma goes civil: can a powder save trauma victims?
Disease control CompletedThis study tested a freeze-dried plasma product that can be mixed with water in 6 minutes, avoiding the long thaw time of standard plasma. It included 42 trauma patients with severe bleeding who needed blood transfusions. The goal was to see if faster plasma delivery could improv…
Phase: PHASE3 • Sponsor: University Hospital, Lille • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New study tests best emergency breathing tube for trauma victims
Disease control CompletedThis study looked at over 2,000 trauma patients who needed help breathing before arriving at the hospital. Half were given a supraglottic airway device (like an LMA or King tube) first, while the other half received standard care. The goal was to see which approach led to more pa…
Phase: NA • Sponsor: Jason Sperry • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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New leg bone plate system passes safety check in small study
Disease control CompletedThis study looked at how safe and effective the JuniOrtho plating system is for treating congenital deformities and fractures in the lower limbs of 30 children and adults. The device is a metal plate and screws used during surgery to hold bones in place while they heal. Researche…
Sponsor: Orthofix s.r.l. • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Checklist could be lifesaver for trauma patients
Disease control CompletedThis study tested whether using the World Health Organization's trauma care checklist helps injured patients recover better. Sixty adults with trauma were randomly assigned to standard care or care with the checklist. Researchers measured pain, injury severity, complications, and…
Phase: NA • Sponsor: Khyber Teaching Hospital • Aim: Disease control
Last updated Jun 26, 2026 18:46 UTC
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New rapid test for infection and inflammation put to the test
Diagnosis CompletedThis study looked at how well a new, quick finger-prick test (LumiraDx CRP) measures CRP levels compared to a standard lab test. CRP is a marker of infection, inflammation, or tissue injury. 79 adults with symptoms of these conditions took part. The goal was to see if the new tes…
Sponsor: LumiraDx UK Limited • Aim: Diagnosis
Last updated Jun 27, 2026 13:07 UTC
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AI spots broken bones better than doctors alone?
Diagnosis CompletedThis study tested an artificial intelligence (AI) program called Carebot AI Bones to see how well it finds fractures on X-rays. Researchers compared the AI's performance to that of experienced radiologists using 600 X-rays from both children and adults. The goal was to see if the…
Sponsor: Carebot s.r.o. • Aim: Diagnosis
Last updated Jun 27, 2026 11:02 UTC
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AI boosts fracture detection in ER, study shows
Diagnosis CompletedThis study tested whether an AI tool called Boneview helps clinicians spot fractures on X-rays more accurately. 18 doctors and other health professionals reviewed 500 X-ray images, half with fractures and half without, first without AI and then with AI assistance. The goal was to…
Sponsor: Oxford University Hospitals NHS Trust • Aim: Diagnosis
Last updated Jun 27, 2026 07:59 UTC
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New scanner could speed up fracture diagnosis with less radiation
Diagnosis CompletedThis study tested whether a cone-beam CT scanner (Newtom 5G) can detect and classify fractures of the arms and legs as accurately as a standard CT scan. 43 adults with suspected fractures received both scans. Researchers compared how well each scan identified the type of fracture…
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Diagnosis
Last updated Jun 26, 2026 13:37 UTC
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Spine procedure put to the test against sham for osteoporosis fracture pain
Symptom relief CompletedThis study tested whether a procedure called vertebroplasty (injecting cement into a broken spine bone) relieves pain better than a sham (fake) procedure in people with osteoporosis. 52 adults aged 50 and older with recent spine fractures took part. The main goal was to measure p…
Phase: NA • Sponsor: Spine Centre of Southern Denmark • Aim: Symptom relief
Last updated Jun 27, 2026 13:01 UTC
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Spine fracture pain: which procedure works best?
Symptom relief CompletedThis study compared four minimally invasive procedures—vertebroplasty, kyphoplasty, stentoplasty, and thermal facet ablation—for treating pain from vertebral compression fractures. Researchers enrolled 1000 adults with chronic back pain due to these fractures. The goal was to see…
Phase: NA • Sponsor: Szeged University • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Robot buddy calms kids during bandage changes
Symptom relief CompletedThis study tested whether a social robot could reduce fear and pain in children aged 5 to 10 during wound dressing. Sixty children were split into two groups: one interacted with the robot while getting their wound dressed, and the other received standard care. Researchers measur…
Phase: NA • Sponsor: Ondokuz Mayıs University • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Virtual rehab could ease pain after spine fractures
Symptom relief CompletedThis study tested whether a virtual rehabilitation program called VIVA is feasible for people with spine fractures caused by osteoporosis. The program includes weekly online sessions to help reduce pain and improve movement and quality of life. The study involved 34 participants …
Phase: NA • Sponsor: University of Waterloo • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Ketamine may cut opioid needs for trauma patients
Symptom relief CompletedThis study looked at whether giving a low dose of ketamine continuously could lower the amount of strong painkillers (opioids) needed by people with serious injuries. The goal was to see at least a 25% reduction in opioid use over 48 hours while still controlling pain just as wel…
Phase: PHASE3 • Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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Paws for recovery: therapy dogs get trauma patients moving
Symptom relief CompletedThis study looked at whether walking with a therapy dog helps adult trauma patients move more during their hospital stay. Sixty-four patients each took two walks—one with a dog and one without—and reported their pain, anxiety, and motivation. The goal was to see if animal-assiste…
Phase: NA • Sponsor: Andrew Bernard • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Spinal fracture study: which injection technique works best?
Symptom relief CompletedThis study looked at two methods of injecting bone cement into fractured vertebrae in elderly patients with osteoporosis. 196 patients were randomly assigned to receive either a one-sided or two-sided injection. The goal was to see which approach better reduces pain and improves …
Phase: NA • Sponsor: Igor Movrin • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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Spine surgery Patients' data collected to improve future care
Knowledge-focused CompletedThis study gathered information from 193 adults who had surgery or orthopedic treatment for spine problems. Researchers collected clinical, functional, and social data to create a detailed database. The goal was to better understand patient outcomes and standardize how data is co…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New score could save lives of motorcycle crash victims
Knowledge-focused CompletedThis study aims to create a simple bedside tool that helps doctors quickly identify motorcycle accident victims with chest injuries who are at high risk of dying. Researchers will analyze data from 1250 patients to build and test the tool, focusing on factors like helmet use and …
Sponsor: Antalya Health Sciences University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Do trauma patients really need that Full-Body scan?
Knowledge-focused CompletedThis completed study looked at 510 trauma patients who had no signs of nerve damage. Researchers wanted to see if getting a full-body CT scan actually changed how doctors managed their care. The goal is to find out if these scans are truly helpful or just add cost and time.
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Tourniquets before hospital: help or hype?
Knowledge-focused CompletedThis study looked at 55 adults with arm or leg injuries to see if using a tourniquet before reaching the hospital made a difference. Researchers compared those who had a tourniquet placed to those who did not, checking for shock, blood transfusions, and other complications. The g…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Golden hour under the microscope: trauma care timing studied
Knowledge-focused CompletedThis study looked at 265 severely injured adults in France to see if getting them to the hospital within the recommended 60 minutes (the 'golden hour') improves their chances of survival. Researchers checked if following these time guidelines helped patients live at least 24 hour…
Sponsor: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Fall risk calculator could save lives by predicting who needs urgent care
Knowledge-focused CompletedResearchers looked at records from over 58,000 adults who had fall injuries to build a simple scoring system that estimates the chance of dying within 30 days. The tool uses age, sex, and vital signs taken in the emergency room. This study did not test any treatment—it only aimed…
Sponsor: Mackay Memorial Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Can tailored shakes help seniors bounce back from trauma?
Knowledge-focused CompletedThis pilot study tested whether a personalized nutrition plan using up to three Ensure shakes a day is practical for older adults (60+) recovering from a serious injury. Forty participants were randomly assigned to either the nutrition plan or standard care. The study did not mea…
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Blood transfusion trends in trauma: what worked and what Didn't?
Knowledge-focused CompletedThis study looked back at the medical records of 137 severely injured trauma patients who needed large blood transfusions between 2020 and 2025. Researchers analyzed how different transfusion strategies, such as balanced ratios and whole blood use, affected 30-day survival and ot…
Sponsor: Mariah Arif • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Does vitamin d help broken bones heal? new study investigates
Knowledge-focused CompletedThis study looked at whether vitamin D levels affect how well broken bones heal in young adults aged 18 to 25. Researchers measured vitamin D at the time of injury and tracked healing for up to a year. The goal was to understand if low vitamin D is linked to slower healing or com…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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New device aims to cut spine screw errors in half
Knowledge-focused CompletedThis study tested a new lightweight device called PYTHEAS ODYSSEE that helps surgeons place screws in the spine more accurately. Fourteen adults having spine surgery used the device to guide screw placement. The goal was to see if the device reduces screw misplacement and is safe…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Parents' hidden trauma after Child's ICU stay revealed
Knowledge-focused CompletedThis study looked at how parents cope emotionally after their child is hospitalized in intensive care for a severe injury. Researchers checked for signs of anxiety, depression, and post-traumatic stress in 62 parents, 3 to 6 months after the child left the ICU. The goal was to un…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Hidden in plain sight: old CT scans may predict fractures better than current tests
Knowledge-focused CompletedThis study looked at whether using regular CT scans (already done for other reasons) can better predict the risk of spine fractures in people over 50, compared to the standard FRAX risk score. Researchers analyzed CT images from nearly 2,800 adults taken five years apart. The goa…
Sponsor: Technical University of Munich • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Frailty index may predict trauma outcomes in seniors
Knowledge-focused CompletedThis study tested a simple frailty score (TSFI) to see if it can predict complications and death in trauma patients aged 65 and older. Researchers enrolled 500 patients across multiple hospitals. The goal was to improve care by identifying high-risk patients early, not to provide…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Obesity's impact on hospital stays for seniors after injury examined
Knowledge-focused CompletedThis study looked at how obesity affects the hospital course and outcomes of trauma patients aged 60 and older. Researchers compared obese and non-obese patients to see if obesity leads to longer stays, more complications, or higher costs. The goal was to clarify conflicting repo…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Organized trauma networks may cut deaths after severe injury
Knowledge-focused CompletedThis study looked at whether a structured regional health system, where trauma centers are organized by level of care, reduces deaths within 28 days after severe injury. Researchers compared outcomes for 2193 severely injured patients treated in a structured system versus a non-s…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Spinal fracture patients: did integrative korean medicine help? new study looks back at real-world results
Knowledge-focused CompletedThis study looked back at medical records and conducted phone surveys of 70 patients who were treated for vertebral compression fractures with integrative Korean medicine at four hospitals. The goal was to see how well the treatment worked for pain and disability, both during the…
Sponsor: Jaseng Medical Foundation • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Can a simple score predict who lives after trauma? new study tests it in iraq
Knowledge-focused CompletedThis study checked how well the Trauma and Injury Severity Score (TRISS) predicts survival and the need for intensive care or surgery in 204 trauma patients at one hospital in Iraq. Researchers measured the score within 6 hours of arrival and tracked outcomes. The goal is to see …
Sponsor: Al-Nahrain University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Arm surgery nerve block study also checks eye pressure
Knowledge-focused CompletedThis study looked at how different amounts of numbing medicine given around the collarbone affect pain relief and side effects during arm surgery. Researchers also used ultrasound to measure the nerve behind the eye to see if it relates to brain pressure. 64 patients aged 18 to 5…
Phase: NA • Sponsor: Pamukkale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Smarter scans: new score could slash unnecessary radiation in kids with trauma
Knowledge-focused CompletedResearchers studied 407 children under 18 who had whole-body CT scans after trauma. They looked at injury details, physical exams, and lab results to create a scoring system called WHOLE. The goal is to help emergency doctors decide when a full-body scan is truly needed, reducing…
Sponsor: Ankara City Hospital Bilkent • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Severe trauma and clotting: new study reveals hidden risks
Knowledge-focused CompletedThis study looked at 263 severely injured trauma patients to find out how often they develop early blood clotting problems (called trauma-induced coagulopathy) and excessive clot breakdown (hyperfibrinolysis) within the first hour of arriving at the emergency room. Researchers us…
Sponsor: Medical University of Graz • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Massive spine surgery database aims to unlock better treatments
Knowledge-focused CompletedThis study collected information from over 8,000 people who had spine surgery for conditions like degeneration, deformity, or trauma. Researchers gathered X-ray and health data to learn which treatments work best for different patients. The goal was to build a database to answer …
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Ultrasound may make emergency catheter placement safer for trauma patients
Knowledge-focused CompletedThis study tested whether using ultrasound to guide the placement of catheters in the femoral artery and vein (in the groin) reduces complications in severely injured patients in the intensive care unit. The trial involved 136 adults with severe trauma who needed these catheters.…
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Emergency MRI may alter treatment plans for spine injury patients
Knowledge-focused CompletedThis completed study looked at 150 adults with thoraco-lumbar spine injuries to see if adding an emergency MRI to a standard CT scan changes how doctors treat them. The researchers compared treatment plans before and after the MRI, including options like rest, minimally invasive …
Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Spine fracture study: surgery vs. no surgery – which is better?
Knowledge-focused CompletedThis completed study looked at 40 adults with certain types of spine fractures in the chest or lower back that did not cause nerve problems. Researchers compared outcomes between patients who had surgery (spinal fusion) and those who received conservative care like bracing and ex…
Sponsor: Sklifosovsky Institute of Emergency Care • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Massive study reveals how neck and facial bleeding affects trauma victims
Knowledge-focused CompletedThis study looked at 15,000 trauma patients treated at a Swedish hospital over 10 years. Researchers focused on those with serious neck or face injuries to understand what causes deadly bleeding and how it is managed. The goal is to improve care for future patients with these inj…
Sponsor: Karolinska University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Spine fracture study: surgery or not?
Knowledge-focused CompletedThis study looked at 80 adults with specific types of spine fractures (A3 and A4) that had a certain injury score (4 or 5). Patients were randomly assigned to receive either surgery or non-surgical care. The researchers measured pain, bone healing, and spine shape to see which ap…
Phase: NA • Sponsor: Ahmed Hamed Kassem Abdelaal • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC