New study tests best emergency breathing tube for trauma victims

NCT ID NCT04100564

Completed Disease control Sponsor: Jason Sperry Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at over 2,000 trauma patients who needed help breathing before arriving at the hospital. Half were given a supraglottic airway device (like an LMA or King tube) first, while the other half received standard care. The goal was to see which approach led to more patients surviving the first 24 hours. The trial took place across 17 ambulance services and trauma centers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Supraglottic airway device (e.g., LMA, King, i-gel)
What this could lead to: If successful, this could establish a better standard for emergency airway management in trauma, potentially saving more lives within the first 24 hours.
What could go wrong: This is a completed trial, but results may not apply to all trauma settings or patient types. The intervention is a device, not a drug, so benefits may be modest and depend on paramedic training.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Accidental Injuries injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AIRWAY CONTROL TRAUMA INJURY

Contacts and locations

Locations

Allegheny General Hospital

Pittsburgh, Pennsylvania, 15212, United States
East Carolina University

Greenville, North Carolina, 27835, United States
Emory University

Atlanta, Georgia, 30303, United States
John H. Stroger Hospital of Cook County

Chicago, Illinois, 60612, United States
Mount Sinai Hospital

Chicago, Illinois, 60608, United States
Northwestern Memorial Hospital

Chicago, Illinois, 60611, United States
Oregon Health & Science University

Portland, Oregon, 97239, United States
Tulane University

New Orleans, Louisiana, 70112, United States
UPMC

Pittsburgh, Pennsylvania, 15261, United States
University of Chicago

Chicago, Illinois, 60637, United States
University of Louisville

Louisville, Kentucky, 40208, United States
University of Pittsburgh

Pittsburgh, Pennsylvania, 15213, United States
Vanderbilt University

Nashville, Tennessee, 37235, United States
Washington University at St. Louis

St Louis, Missouri, 63110, United States

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