Spastic cerebral palsy

This trial tests whether a 12-week program of core stabilization exercises can improve balance, trunk control, and gross motor function in children with spastic diplegic cerebral palsy. Sixty children who can walk with some assistance will be randomly assigned to receive either s…

This trial tests whether structured eye-movement exercises can improve balance and motor skills in children aged 6 to 10 with spastic diplegia, a form of cerebral palsy. Participants perform exercises like tracking moving targets and shifting gaze quickly, alongside standard phys…

This study follows 25 people aged 2 to 65 with cerebral palsy or brain damage from lack of oxygen who have already received a new gene therapy given as a nose spray. The therapy delivers 15 genes meant to repair the brain, reduce inflammation, and improve movement and thinking. R…

This study tests whether adding robot-assisted walking training to standard physical therapy helps children with cerebral palsy move better and breathe easier. Twenty-four children aged 8-18 will receive either standard therapy alone or standard therapy plus robotic walking sessi…

This study tests whether a remote physiotherapy program, based on the neurodevelopmental treatment (Bobath) model, can improve gross motor skills and daily function in children with cerebral palsy. Twenty children aged 6 months to 6 years will participate, with a caregiver helpin…

This study compares two types of physical therapy for children aged 6 to 10 with diplegic cerebral palsy: scooter board activities and core stability exercises. The goal is to see which better improves trunk control and balance. Forty children will participate, and their progress…

This trial tests whether adding Therapeutic Listening, a music-based auditory therapy, to a standard exercise program improves balance, trunk control, and reaction time in children with spastic diplegic cerebral palsy. Sixty children will receive either exercise alone or exercise…

This pilot study tests whether virtual reality games or functional strength training can improve arm function in children with cerebral palsy. Ten participants will be randomly assigned to one of two home-based interventions, each lasting six weeks. Researchers will measure chang…

This trial tests whether adding a robotic glove to mirror therapy can improve arm and hand function in children with hemiparetic cerebral palsy. Participants will receive either robot-assisted or conventional mirror therapy alongside standard neurodevelopmental treatment for six …

This pilot study tests whether a home-based training program using joystick-operated ride-on toys can help children aged 3-8 with hemiplegia improve arm function. Children will use their affected arm to drive the toy through playful challenges, compared to a creative upper extrem…

This study tests whether a mild electrical current applied to the scalp, called transcranial direct current stimulation (tDCS), can enhance motor learning in children with unilateral spastic cerebral palsy. Participants aged 6 to 17 will receive tDCS or a sham during five days of…

This trial tests whether a special training program called Reactive Functional Motor Challenge Training can improve dynamic balance and functional mobility in children with spastic diplegic cerebral palsy. The training uses equipment like balance pads, cones, therapy balls, and a…

This study compares a special exercise program called Coordinative Locomotor Training (CLT) to regular physiotherapy for children aged 8 to 12 with spastic hemiplegic cerebral palsy, a condition that causes stiffness on one side of the body. CLT uses running and skating movements…

This study tests whether augmented reality (AR) games can improve walking and balance in children with cerebral palsy. Forty children will either do exercises wearing AR goggles or receive standard physical therapy. The goal is to see if the AR approach is more effective and enga…

This study tests two different therapies—digital mirror therapy and action observation therapy—to see which better improves arm movement and grip strength in children with hemiplegia (one-sided weakness). Forty-five children aged 6 to 8 will participate. The goal is to find a sim…

This trial tests a robotic exoskeleton called the CPWalker to help children with cerebral palsy improve their walking. The device supports the child's weight and assists leg movements during walking practice. The study includes 30 participants aged 11 to 21 with spastic diplegia.…

This study looks at whether a special exercise method called blood flow restriction training can help children with hemiparetic cerebral palsy (CP) improve their hand grip strength. The method uses a cuff to lightly restrict blood flow during low-intensity exercises, which may bu…

This study tests whether 3 months of intensive leg exercise (walking, kicking, jumping, and climbing with small ankle weights) can improve walking and daily function in 60 young children with spastic diplegia caused by prematurity. The exercise is done 1 hour a day, 4 days a week…

This study looks at the cost and benefits of a two-week day camp for children with mild to moderate arm weakness (hemiparesis) from cerebral palsy or brain injury. In the first week, children wear a constraint on their stronger arm to encourage use of the weaker arm, followed by …

This study tests a gentle hands-on technique called Strain Counter-Strain to relax tight jaw and neck muscles in 30 children with spastic cerebral palsy, ages 4 to 8. The goal is to improve mouth opening, reduce drooling, and make eating easier. Results are measured after one mon…

This study compares two types of therapy for children aged 8 to 12 with spastic diplegic cerebral palsy. One group uses play-based activities like puzzles and arts and crafts, while the other uses standard exercises with resistance bands and weights. The goal is to see which appr…

This study looks at whether walking on a path with lights that show where to step can improve how children with spastic diplegia (a type of cerebral palsy) walk. Thirty children aged 5 to 8 with mild spasticity will walk on the light pathway, and researchers will measure changes …

This study tests a dual-task training program for children aged 6-8 with unilateral cerebral palsy. About 70 participants will be split into two groups: one doing balance exercises while also performing fine motor tasks, and the other doing single-task exercises. The goal is to s…

This study looks at whether adding tolperison to botulinum toxin injections helps reduce muscle stiffness and nerve pain in stroke survivors. About 40 adults with spastic hemiplegia (one-sided paralysis) will be followed. Researchers will measure spasticity and walking speed to s…

This study looked at 60 children aged 6 to 10 with hemiplegic cerebral palsy to see which type of balance training works better: playing on a Wii Balance Board or doing reactive balance exercises. Both groups also did standard physical therapy three times a week for eight weeks. …

This study looks at whether doing arm exercises on a vertical surface (like a wall) or a horizontal surface (like a table) makes a bigger difference in hand skills and trunk control for children with bilateral cerebral palsy. Thirty children aged 5 to 8 will take part in a 3-mont…

This pilot study tests whether constraint-induced movement therapy (CIMT) can be effectively delivered via video in the homes of 10 children aged 4-10 with hemiplegic cerebral palsy. The therapy involves encouraging use of the weaker arm while restraining the stronger one. Resear…

This study tests whether adding a gentle, non-invasive nerve stimulation on the ear (taVNS) to standard physical therapy can reduce muscle stiffness, improve movement, and boost quality of life in children with spastic cerebral palsy. Eighteen children aged 8-18 will be split int…

This study looks at whether virtual reality games designed for hand-arm training can improve hand function in children with hemiplegic cerebral palsy. Seventeen children will either play VR games or do standard hand exercises for 40 hours over two weeks. Researchers will measure …

This study explores how children with bilateral cerebral palsy (a condition affecting movement on both sides of the body) step, by adding or reducing body weight during walking tasks. Researchers will measure joint movements, forces, and muscle activity to understand lower limb i…

This study tests whether a special type of X-ray called DXA, taken while lying down, can measure spine curves as well as standard standing X-rays in people with scoliosis. About 20 participants will have both types of images taken, and researchers will compare the results and ask…

This study checks whether a play-based test of arm and hand movements, called the Melbourne Assessment-2, is reliable when done through telehealth for children with hemiplegic cerebral palsy. About 35 children ages 2 to 10 will attend one in-person visit and one telehealth visit,…