Radiodermatitis

This early-stage study tests a new imaging agent called 18F-4FN for PET scans to safely detect inflammation in the body. It involves 55 adults with cancer who are on immunotherapy or have suspected inflammation. The goal is to see if this agent can highlight areas of inflammation…

This study is testing a software tool called Belle.ai that uses artificial intelligence to help doctors diagnose common skin diseases. About 400 patients at dermatology clinics will have three photos taken of their skin condition. The AI will analyze the photos and suggest possib…

This early-stage trial tests a cream made from inactivated Akkermansia muciniphila bacteria to prevent skin injury in 40 breast or head/neck cancer patients receiving radiation. The cream is applied three times daily to the radiation area. The main goal is to see if it is safe an…

This study tests whether a chlorhexidine spray can prevent severe skin reactions caused by radiation therapy in people with nasopharyngeal cancer. About 148 participants will use the spray or a placebo during their treatment. The goal is to see if the spray reduces the chance of …

This study tests a cream called Pinoxin to see if it can prevent skin injuries caused by radiation therapy in cancer patients. About 202 adults receiving high-dose radiation will be randomly assigned to use either Pinoxin or a placebo cream. The main goal is to see if Pinoxin low…

This study tests a new cream made from amino acids to prevent skin damage caused by radiation therapy in people with head and neck cancer. About 40 participants will use the cream during their radiation treatment. The goal is to see if it reduces skin redness, pain, and treatment…

This study tests whether a gel containing diclofenac, a common anti-inflammatory drug, can prevent severe skin irritation caused by radiation therapy. About 156 adults with head/neck or breast cancer will apply the gel or a placebo to the treated skin three times daily during the…

This study tests a liquid made from cockroach extract (Meilian Fuxin) to prevent severe skin damage in head and neck cancer patients receiving radiation therapy. About 60 participants will apply the solution to their skin during treatment. The goal is to see if it reduces the ris…

This study tests a hydrogel made from bacterial cellulose and coconut oil monolaurin to prevent severe skin reactions in Filipino women with breast cancer undergoing radiation therapy. About 54 participants will apply either the hydrogel or a placebo cream daily. The goal is to s…

This study tests whether taking alpha lipoic acid, a common antioxidant supplement, can prevent or reduce skin irritation caused by radiation therapy in breast cancer patients. Researchers will enroll 40 women with early-stage breast cancer who are scheduled for radiation. The go…

This study tests whether a special light therapy can reduce skin damage caused by radiation treatment in women with breast cancer. 60 women who have had breast-conserving surgery and are scheduled for radiation will either receive standard skin care alone or standard care plus po…

This study tests a new cream made from Prussian blue nanoparticles, combined with a special light therapy, to heal severe (grade III) radiation skin burns in head and neck cancer patients. The cream works by mopping up harmful molecules and, when activated by light, produces gent…

This study tests whether a special dressing (Mepilex Lite) placed inside the anal canal, combined with a pain-relieving suppository (indomethacin), can better treat acute radiation dermatitis—painful, red, or ulcerated skin—caused by radiotherapy for rectal cancer. About 274 adul…

This study tests whether taking taurine granules before daily radiation can reduce painful mouth sores and skin burns in 160 head and neck cancer patients. Half get taurine, half get a placebo, and researchers track side effect severity. If effective, it could offer a simple, low…

This study tests a group counseling program called Healing HEARTS to help people with conditions like obesity, skin disease, cancer, HIV, diabetes, or chronic pain deal with internalized stigma. Participants will either join the counseling program or a peer support group. The goa…

This study collects biological samples—like blood, skin biopsies, and swabs—from people with or at risk for skin diseases, as well as healthy volunteers. Researchers will use these samples to study the causes of skin conditions and explore potential treatments. Up to 700 particip…

This study looks at whether repeated sessions of hyperbaric oxygen therapy (HBOT) can damage DNA in people who have had radiation for cancer. HBOT is used to help heal tissues damaged by radiation, but it also creates reactive oxygen molecules that might harm DNA. Researchers wil…

This study looks at how cannabis use and stopping it affect sleep, daily body rhythms, and sensitivity to light in healthy young adults aged 18-25. Researchers will compare regular cannabis users with non-users using sleep monitors, light tests, and pupil measurements. The goal i…

This pilot study is measuring prednisolone levels in 120 people with inflammatory diseases like thyroid eye disease, vasculitis, COPD, asthma, and others. Participants take high-dose prednisolone as part of their routine care, and researchers take timed blood samples to see how t…

This study looks at 320 adults who are about to start strong immune-suppressing therapy and have already had at least two COVID-19 shots. Researchers want to find out if giving a COVID-19 booster right before starting therapy or waiting six months provides better protection. Part…

This study looks at how skin conditions related to cancer or cancer treatments affect the well-being of cancer patients and survivors. About 1,025 participants will fill out questionnaires about their skin condition. The goal is to better understand these effects and improve trea…