Could a probiotic cream shield cancer patients from radiation burns?

NCT ID NCT07635277

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This early-stage trial tests a cream made from inactivated Akkermansia muciniphila bacteria to prevent skin injury in 40 breast or head/neck cancer patients receiving radiation. The cream is applied three times daily to the radiation area. The main goal is to see if it is safe and tolerable, and to measure how many patients develop moderate to severe skin reactions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BREAST CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Jintang County First People's Hospital

    RECRUITING

    Chengdu, Sichuan, 610400, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • West China Hospital of Sichuan University

    RECRUITING

    Chengdu, Sichuan, 610041, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

inactivated Akkermansia muciniphila bacteria (topical preparation)

What this could lead to

If it works, this could point toward a simple cream to prevent or reduce skin damage from radiation therapy.

What could go wrong

This is a very early Phase 1 trial with only 40 people, so it is mainly checking safety. It may not prove effective, and results may not apply to all patients.

Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm head and neck cancer Head and Neck Neoplasms nasopharyngeal carcinoma radiodermatitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.