Could a probiotic cream shield cancer patients from radiation burns?

NCT ID NCT07635277

Recruiting now Prevention Sponsor: West China Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tests a cream made from inactivated Akkermansia muciniphila bacteria to prevent skin injury in 40 breast or head/neck cancer patients receiving radiation. The cream is applied three times daily to the radiation area. The main goal is to see if it is safe and tolerable, and to measure how many patients develop moderate to severe skin reactions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: inactivated Akkermansia muciniphila bacteria (topical preparation)
What this could lead to: If it works, this could point toward a simple cream to prevent or reduce skin damage from radiation therapy.
What could go wrong: This is a very early Phase 1 trial with only 40 people, so it is mainly checking safety. It may not prove effective, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm head and neck cancer Head and Neck Neoplasms nasopharyngeal carcinoma radiodermatitis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RADIATION-INDUCED SKIN INJURY

Contacts and locations

Locations

Jintang County First People's Hospital
RECRUITING

Chengdu, Sichuan, 610400, China
West China Hospital of Sichuan University
RECRUITING

Chengdu, Sichuan, 610041, China

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