Could a simple cream shield cancer patients from radiation burns?

NCT ID NCT07545720

Recruiting now Prevention Sponsor: Fudan University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a cream called Pinoxin to see if it can prevent skin injuries caused by radiation therapy in cancer patients. About 202 adults receiving high-dose radiation will be randomly assigned to use either Pinoxin or a placebo cream. The main goal is to see if Pinoxin lowers the rate of moderate to severe skin burns.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Pinoxin (a hydrogen-donor modified SOD skin protective agent)
What this could lead to: If it works, this could provide a simple preventive cream to reduce painful skin burns for cancer patients undergoing radiation therapy.
What could go wrong: This is a Phase 2 trial with 202 participants, so it is still early. The placebo group may show similar results, and the cream may not reduce severe skin injury as hoped.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer radiodermatitis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANCER PATIENTS UNDERGONING RADIOTHERAPY

Contacts and locations

Locations

Fudan University Shanghai Cancer Center
RECRUITING

Shanghai, Shanghai Municipality, 200032, China
Fudan University Shanghai Cancer Center
RECRUITING

Shanghai, China

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