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Lower respiratory tract disorder
MONDO:0000270A disease involving the lower respiratory tract.
Also known as: disease of lower respiratory tract, disease or disorder of lower respiratory tract, disorder of lower respiratory tract, lower respiratory tract disease, lower respiratory tract disease or disorder
7952 clinical trials for this condition and its sub-types, 18 tagged with Lower respiratory tract disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Lower respiratory tract disorder
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Lung disorder 251 trials · 7,091 incl. sub-types
33 sub-types
- Lung neoplasm 1,371 trials · 4,046 incl. sub-types Sub-types →
- Obstructive lung disease 36 trials · 1,074 incl. sub-types Sub-types →
- Respiratory failure 280 trials · 790 incl. sub-types Sub-types →
- Interstitial lung disease 257 trials · 729 incl. sub-types Sub-types →
- Pneumonitis 15 trials · 646 incl. sub-types Sub-types →
- Bronchiolitis 51 trials · 104 incl. sub-types Sub-types →
- Acute lung injury 90 trials
- Fungal lung infectious disease 6 trials · 57 incl. sub-types Sub-types →
- Pulmonary non-tuberculous mycobacterial infection 48 trials
- Aspiration pneumonia 33 trials
- Acute chest syndrome 30 trials
- Middle lobe syndrome 29 trials
- Pulmonary systemic sclerosis 27 trials
- Pulmonary coin lesion 24 trials
- Pulmonary alveolar proteinosis 9 trials · 13 incl. sub-types Sub-types →
- Pulmonary artery disease 12 trials
- Rheumatoid arthritis-associated interstitial lung disease 12 trials
- Occupational lung disease 4 trials · 8 incl. sub-types Sub-types →
- Restrictive pulmonary disease 8 trials
- Neonatal aspiration syndrome 1 trial · 6 incl. sub-types Sub-types →
- Lung abscess 3 trials
- Pneumonic plague 3 trials
- Hantavirus pulmonary syndrome 2 trials
- Pulmonary immaturity 2 trials
- Wilson-Mikity syndrome 0 trials
- Dystrophic pulmonary ossification 0 trials
- Pulmonary alveolar microlithiasis 0 trials
- Pulmonary embolism and infarction 0 trials
- Pulmonary plasma cell granuloma 0 trials
- Pulmonary venoocclusive disease 0 trials Sub-types →
- Shrinking lung syndrome 0 trials
- Silo filler disease 0 trials
- Vanishing lung syndrome 0 trials
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Tracheal disorder 6 trials · 1,091 incl. sub-types
8 sub-types
- Chronic obstructive pulmonary disease 937 trials · 1,054 incl. sub-types Sub-types →
- Tracheal stenosis 20 trials
- Tracheitis 2 trials · 7 incl. sub-types Sub-types →
- Congenital tracheomalacia 6 trials
- Trachea neoplasm 2 trials · 5 incl. sub-types Sub-types →
- Isolated tracheo-esophageal fistula 2 trials
- Laryngotracheoesophageal cleft 1 trial Sub-types →
- Tracheal calcification 0 trials
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Bronchial disorder 19 trials · 1,012 incl. sub-types
6 sub-types
- Asthma 725 trials · 820 incl. sub-types Sub-types →
- Bronchiectasis 119 trials · 120 incl. sub-types Sub-types →
- Bronchitis 24 trials · 50 incl. sub-types Sub-types →
- Bronchial neoplasm 20 trials · 38 incl. sub-types Sub-types →
- Non-syndromic bridging bronchus 0 trials
- Non-syndromic congenital bronchial atresia 0 trials
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Pleural disorder 15 trials · 177 incl. sub-types
5 sub-types
- Pleural neoplasm 5 trials · 97 incl. sub-types Sub-types →
- Pneumothorax 35 trials · 45 incl. sub-types Sub-types →
- Pleural empyema 20 trials Sub-types →
- Pleurisy 2 trials · 9 incl. sub-types Sub-types →
- Congenital chylothorax 0 trials
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Tracheobronchitis 5 trials · 55 incl. sub-types
2 sub-types
- Bronchitis 24 trials · 50 incl. sub-types Sub-types →
- Tracheitis 2 trials · 7 incl. sub-types Sub-types →
Most studied deeper sub-types
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Triple threat vaccine aims to shield seniors from three winter viruses
Vaccine OngoingThis early-stage study tests a new vaccine called VXB-251 in 240 healthy adults aged 60-83. The vaccine is designed to protect against three viruses that can cause serious lung infections: RSV, hMPV, and PIV3. Researchers will check if the vaccine is safe and how well it triggers…
Phase 1 • Sponsor: Sanofi • Aim: Vaccine
Last updated Jun 27, 2026 12:35 UTC
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Major RSV vaccine trial for seniors nears completion
Vaccine OngoingThis Phase 3 study tests whether a single dose of Pfizer's RSV vaccine (RSVpreF) can prevent lower respiratory tract illness caused by RSV in adults aged 60 and older. Over 38,800 participants across multiple countries received either the vaccine or a placebo. The study also look…
Phase 3 • Sponsor: Pfizer • Aim: Vaccine
Last updated Jun 27, 2026 09:00 UTC
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RSV shot for moms: does it shield newborns?
Prevention OngoingThis study checks how well the RSV vaccine (ABRYSVO) works when given to pregnant women to protect their babies from severe RSV illness. Researchers will look at health records of infants hospitalized with breathing problems in Australia. They want to see if vaccinated moms' babi…
Sponsor: Pfizer • Aim: Prevention
Last updated Jun 27, 2026 07:58 UTC