Borderline personality disorder

This study tests whether combining transcranial magnetic stimulation (TMS) with a short emotion regulation training program can help people with borderline personality disorder (BPD) better manage their emotions. TMS aims to improve brain circuits involved in emotion control, whi…

This trial is developing and testing a peer-led program called the Trauma Recovery Program for family members and significant others of people with borderline personality disorder. The program aims to reduce posttraumatic stress symptoms that can arise from living with or caring …

This trial investigates whether a psychological program called DBT-LIVE, which focuses on identity disturbance, can help people with borderline personality disorder (BPD). Around 112 participants will be randomly assigned to receive either DBT-LIVE or their usual treatment. Resea…

This pilot study will test whether two intravenous infusions of ketamine, given 24 hours apart, can quickly reduce symptoms in 38 adults with severe borderline personality disorder (BPD). Participants also receive standard psychiatric care. The main goal is to see if symptoms imp…

This study tests whether a 10-week virtual group therapy, where people write about their traumatic experiences, can reduce PTSD symptoms in adults who also have borderline personality disorder (BPD) traits. The therapy is called Group Extended Written Exposure Therapy (GE-WET). R…

This pilot study will test whether a brief ear acupuncture program, delivered by specially trained nurses, is feasible and helpful for adults hospitalized with borderline personality disorder. Fifteen participants will receive five ear acupuncture sessions over nine days, in addi…

This study compares a new trauma-focused therapy (MBT-TF) with standard therapy for adults who have both borderline personality disorder and complex PTSD. The goal is to see if the new approach is practical and helpful for reducing symptoms. Forty participants will be followed fo…

This study tests sensorimotor psychotherapy, a body-oriented therapy, for people with personality disorders who experienced early childhood trauma. The therapy uses 12 group sessions to teach skills for regulating emotions and body responses. Researchers will compare it to standa…

This study tests whether a version of dialectical behavior therapy (DBT) that has been adapted to fit local cultures can help adults aged 18-45 with borderline personality disorder better manage their emotions and reduce self-harm. The therapy is being studied in a low- and middl…

This study tests whether autobiographical rewriting workshops, added to standard therapy, can help people with borderline personality disorder (BPD) function better socially and at work. 140 participants will either take part in these workshops or do non-specific writing sessions…

This study looks at how emotional regulation varies across the menstrual cycle in autistic women. Researchers will compare them to women with borderline personality disorder, premenstrual dysphoric disorder, and those without any diagnosed condition. The goal is to better underst…

This study checks in with people who received mentalization-based treatment (MBT) for borderline personality disorder more than 10 years ago. Researchers want to see how they are functioning now, whether symptoms have changed, and if the type of MBT they received matters. Partici…

This study uses EEG brain scans to understand how people with borderline personality disorder (BPD) process social rejection. Researchers will measure brain activity while participants play a virtual ball-tossing game designed to make them feel left out. The goal is to identify d…