Borderline personality disorder

This study will test whether living in a self-contained, AI-managed community (called a Microcity) can improve mental health and reduce addiction in adults with conditions like autism, ADHD, substance use disorders, and behavioral addictions. Up to 1 million participants will liv…

This study tests a short case management program for people who have been involuntarily admitted to a psychiatric hospital. The program, designed with input from people who have experienced coercion, provides up to five sessions with a nurse or social worker starting during the h…

This pilot study will test whether two intravenous infusions of ketamine, given 24 hours apart, can quickly reduce symptoms in 38 adults with severe borderline personality disorder (BPD). Participants also receive standard psychiatric care. The main goal is to see if symptoms imp…

This study tests whether a 10-week virtual group therapy, where people write about their traumatic experiences, can reduce PTSD symptoms in adults who also have borderline personality disorder (BPD) traits. The therapy is called Group Extended Written Exposure Therapy (GE-WET). R…

This study tests whether combining ketamine infusions with dialectical behavioural therapy (DBT) can reduce suicidal thoughts more effectively than a placebo plus DBT. About 120 adults with borderline personality disorder and treatment-resistant depression or bipolar disorder wil…

This study tests whether a type of cognitive training called Action-Based Cognitive Remediation (ABCR) can improve thinking skills in people with various psychiatric conditions like depression, schizophrenia, anxiety, PTSD, and autism. Participants will complete computer exercise…

This pilot study will test whether a brief ear acupuncture program, delivered by specially trained nurses, is feasible and helpful for adults hospitalized with borderline personality disorder. Fifteen participants will receive five ear acupuncture sessions over nine days, in addi…

This study compares a new trauma-focused therapy (MBT-TF) with standard therapy for adults who have both borderline personality disorder and complex PTSD. The goal is to see if the new approach is practical and helpful for reducing symptoms. Forty participants will be followed fo…

This study tests sensorimotor psychotherapy, a body-oriented therapy, for people with personality disorders who experienced early childhood trauma. The therapy uses 12 group sessions to teach skills for regulating emotions and body responses. Researchers will compare it to standa…

This study tests whether a version of dialectical behavior therapy (DBT) that has been adapted to fit local cultures can help adults aged 18-45 with borderline personality disorder better manage their emotions and reduce self-harm. The therapy is being studied in a low- and middl…

This study tests whether autobiographical rewriting workshops, added to standard therapy, can help people with borderline personality disorder (BPD) function better socially and at work. 140 participants will either take part in these workshops or do non-specific writing sessions…

This study aims to adapt and validate a French version of the Recovery Assessment Scale (RAS), a questionnaire that measures how people feel about their own recovery from mental health conditions. Researchers will ask 260 adult psychiatric patients in France to fill out the RAS a…

This study looks at how emotional regulation varies across the menstrual cycle in autistic women. Researchers will compare them to women with borderline personality disorder, premenstrual dysphoric disorder, and those without any diagnosed condition. The goal is to better underst…

This study checks in with people who received mentalization-based treatment (MBT) for borderline personality disorder more than 10 years ago. Researchers want to see how they are functioning now, whether symptoms have changed, and if the type of MBT they received matters. Partici…

This study will test a tool called the Health Improvement Profile (HIP) in a mental health inpatient unit. The HIP is a checklist that helps clinicians spot physical health problems like high blood pressure or poor diet in people being treated for mental illness. Researchers will…

This study uses EEG brain scans to understand how people with borderline personality disorder (BPD) process social rejection. Researchers will measure brain activity while participants play a virtual ball-tossing game designed to make them feel left out. The goal is to identify d…

This study aims to better understand psychiatric disorders, thinking problems, and treatment side effects in 2000 cancer patients and their close relatives. Researchers will compare those with and without mental health issues to find patterns and improve care. No new treatments a…

This study will check how much psychiatric clients know about occupational therapy (OT) and whether their expectations are realistic. It will also evaluate how well OT interns explain health information and conduct interviews. Researchers will develop new tools to measure these s…