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127005 trials found · Page 5899 of 6351
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Pneumonia vaccine study aims to sharpen lab tests
Vaccine Recruiting nowThe study will collect serum from 12 participants vaccinated with Gamma-PN to assist with assay development and validation
Phase 1 • Sponsor: GPN Vaccines • Aim: Vaccine
Last updated Jun 27, 2026 07:53 UTC
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Teens rate vaping ads to find what really stops them
Knowledge-focused CompletedThe purpose of the Aim 2 study is to assess the perceived effectiveness of vaping prevention ads among adolescents and young adults and identify which features of video ads predict perceived message effectiveness. Participants will include adolescents aged 13-17 and young adults …
Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jul 03, 2026 00:00 UTC
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Heart rate clues to blood sugar spikes in ICU patients?
Knowledge-focused CompletedHeart rate variability (HRV) is a simple way to check how well the body's automatic nervous system is working. It does this by looking at how the heart rate changes in the electrocardiogram. HRV can be divided into time domain and frequency domain. Time domain indicators assess t…
Sponsor: Shanghai Zhongshan Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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New eye camera aims to make pediatric exams easier
Knowledge-focused CompletedThe goal of this observational study is to test the use of a novel Widefield Confocal Scanning Laser Ophthalmoscope (WiSLO) Optimized for Pediatric and Neonatal Imaging in pediatric and adult subjects who are undergoing clinical evaluation for eye disease or are healthy adult vol…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Sep 05, 2026 00:00 UTC
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Digital dentures may beat traditional ones in tooth health study
Knowledge-focused Not yet recruitingThis study is aimed to compare CAD/CAM (digitally fabricated) metallic partial denture frameworks to conventionally fabricated metallic partial denture frameworks in mandibular Kennedy class-III arches in terms of abutment health and occlusal analysis
Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Colon marker study tracks visibility over 3 years
Knowledge-focused CompletedPost market clinical study that is a chart review of the Spot Ex Endoscopic Marker
Sponsor: Laborie Medical Technologies Inc. • Aim: Knowledge-focused
Last updated Aug 27, 2026 00:00 UTC
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Pelvis fracture recovery: can patients walk right after surgery?
Knowledge-focused Not yet recruitingThe goal of this study to determine if a randomized clinical trial of immediate versus delayed weight bearing after undergoing surgical fixation of a pelvis or acetabulum fracture is feasible. The main questions it aims to answer are: Are surgeons willing to allow inclusion of t…
Sponsor: University of Mississippi Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Back brace showdown: jewett vs. spinomed – which one restricts movement more?
Knowledge-focused By invitation onlyThis project aims to investigate the effects of different hyperextension braces (Jewett and Spinomed) on spinal mobility and posture. Hyperextension braces are commonly prescribed to limit spinal flexion and regulate load distribution, especially in cases of spinal injuries and p…
Sponsor: Mustafa Tahsin Ozer • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:43 UTC
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Liver function may change how tirabrutinib acts in the body
Knowledge-focused CompletedA study to investigate the pharmacokinetics of tirabrutinib in participants with mild, moderate, and severe hepatic impairment compared to healthy participants
Phase 1 • Sponsor: Ono Pharmaceutical Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Scissors or scalpel? new study aims to reduce bleeding in C-Sections
Knowledge-focused Not yet recruitingTo compare between rate of blood loss in uterine incision using scissors and scalpel in caesarean section
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Can a smartphone app get you home faster after pancreas surgery?
Knowledge-focused Not yet recruitingThis feasibility trial has three main objectives: * To investigate the impact of the transmural care pathway TOTeM on the Length of Stay (LOS) for patients undergoing robotic distal pancreatectomy. * To investigate the feasibility of the implementation of TOTeM for patients unde…
Sponsor: Jessa Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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3D goggles may sharpen spine Surgeons' skills
Knowledge-focused Not yet recruitingThis study aims to compare three-dimensional (3D) and two-dimensional (2D) visualization in biportal endoscopic spine surgery using a simulated environment. Surgeons will perform standardized tasks on a spine model while using either 3D or 2D endoscopic systems. The goal is to de…
Sponsor: Felix Corr • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:14 UTC
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Study to track pain and expectations in 200 cancer surgery patients
Knowledge-focused Not yet recruitingThis study includes participants undergoing major hepatic surgery, surgery in the esophagus or stomach, or major surgery on the pancreas performed at Copenhagen University Hospital, Rigshospitalet. The aims of the study 1: To record patients' level of catastrophizing preoperative…
Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:28 UTC
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Sugar tracker: scientists spy on immune Cells' energy use
Knowledge-focused Recruiting nowThe purpose of this study is to understand how cells of the immune system use the common sugar glucose to fuel energy production and as a building block within the cell. Investigators will intravenously infuse a non-radioactive glucose tracer into participants over a few hours an…
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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New sports drink study tests if glycerol boosts hydration
Knowledge-focused CompletedGlycerol and sodium are osmotically-active ingredients that promote fluid retention via renal water reabsorption. The purpose of this study is to compare the effects of a glycerol-electrolyte beverage on fluid balance in healthy euhydrated men and women
Sponsor: PepsiCo Global R&D • Aim: Knowledge-focused
Last updated Jul 17, 2026 00:00 UTC
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New dashboard aims to ease ICU nurse burnout
Knowledge-focused Not yet recruitingIncreasing patient complexity, staffing shortages, and administrative burdens have intensified nurses' workloads, contributing to burnout and reduced job satisfaction. These challenges were particularly evident in the intensive care units (ICU) during the COVID-19 outbreak. With …
Sponsor: Willemijn Berkhout • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:25 UTC
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Pre-surgery rehab shows promise for rare shoulder deformity in child
Symptom relief CompletedThe goal of this observational study (single-patient case report) is to learn whether a structured pre-operative physical therapy rehabilitation program can improve shoulder function, reduce pain, and improve quality of life in an 11-year-old girl with humeral head and shaft defo…
Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Walking patterns reveal clues about back pain
Knowledge-focused CompletedThe goal of this observational case-control study is to learn whether low back pain is associated with changes in gait and related clinical characteristics in adults over 18 years old. The main questions it aims to answer are: * Are gait biomechanics different in people with low…
Sponsor: Arrate Pinto Carral • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Scientists probe oxidative stress in two forms of diabetes
Knowledge-focused Recruiting nowAfter obtaining informed consent, the investigators will recruit 75 patients with T1DM and 75 with LADA with an age ≥ 18 years and ≤ 75 years, of both sexes. All patients will be selected among outpatients attending the Center of Diabetes and Metabolic Diseases of First Departmen…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Can repeating instructions back improve recovery after leg surgery?
Knowledge-focused CompletedThis study aims to determine the effect of discharge education based on the Teach-Back method on patients' learning needs and readiness for hospital discharge following lower extremity surgery. Lower extremity surgeries are associated with pain, limited mobility, and decreased se…
Sponsor: University of Gaziantep • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC