Virginia Commonwealth University
Clinical trials sponsored by Virginia Commonwealth University, explained in plain language.
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Parents key to teen weight loss success, study finds
Disease control CompletedThis study looked at how parents can help teenagers with obesity keep off weight after losing it. Over 400 teens and their parents took part in a program that included healthy eating, exercise, and support. The goal was to see which way of involving parents worked best for long-t…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Disease control
Last updated May 26, 2026 03:17 UTC
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Virtual house calls help kids with weight management
Disease control CompletedThis study tested a new way to treat childhood obesity by replacing some in-person doctor visits with video telehealth sessions. Health coaches worked with families in their homes to build healthy skills. Ten children aged 9-13 with overweight or obesity took part. The goal was t…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Disease control
Last updated May 26, 2026 03:15 UTC
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App aims to keep cirrhosis patients out of the hospital
Disease control CompletedThis study tested whether using a health app (PatientBuddy) and a brain-function test (EncephalApp) could help prevent unnecessary hospital readmissions within 30 days for people with cirrhosis. The study involved 232 patients and their caregivers. The goal was to see if tracking…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Disease control
Last updated May 26, 2026 03:11 UTC
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Could a cough medicine combo help fight opioid addiction?
Disease control CompletedThis early-phase study tested whether adding a medication called AUVELITY (a mix of dextromethorphan and bupropion) to standard buprenorphine/naloxone treatment is safe for people with opioid use disorder. 18 adults on stable buprenorphine treatment took part. Researchers monitor…
Phase: PHASE1, PHASE2 • Sponsor: Virginia Commonwealth University • Aim: Disease control
Last updated May 26, 2026 03:10 UTC
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Community coaching helps african americans shed pounds
Disease control CompletedThis study tested a wellness coaching program called 'house chats' to help African American adults in Petersburg, Virginia, lose weight and improve their health. Twenty-two participants received coaching on physical activity, diet, and weight management. The goal was to see if th…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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App aims to keep liver patients out of the hospital
Prevention CompletedThis study tested whether a smartphone app called PatientBuddy could help people with cirrhosis and their caregivers prevent unnecessary hospital readmissions within 30 days after discharge. The app provided tools and support for managing the condition at home. The trial included…
Sponsor: Virginia Commonwealth University • Aim: Prevention
Last updated May 26, 2026 03:13 UTC
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Rural school program gets kids to eat more fruits and veggies
Prevention CompletedThis study tested a school program to help rural middle school students eat more fruits and vegetables. Over 1,100 seventh graders from ten Virginia schools took part. The program included goal setting, peer leaders, and workshops. Students in the program ate more fruits and vege…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Prevention
Last updated May 26, 2026 03:10 UTC
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Sleep your way to a healthier heart: new study tests sleep extension for heart failure
Symptom relief CompletedThis small pilot study looked at whether gradually extending sleep time, combined with good sleep habits, is possible and helpful for people with a type of heart failure called HFpEF. Ten adults with stable heart failure and poor sleep quality wore activity trackers and kept slee…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated May 26, 2026 03:20 UTC
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Vibrating vest may help Parkinson's patients stop freezing
Symptom relief CompletedThis study tested a wearable device called PDVibe2 that delivers gentle vibrations to improve walking and balance in people with Parkinson's disease. 12 participants completed the trial, which measured changes in gait and movement symptoms. The goal was to see if the device is sa…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated May 26, 2026 03:19 UTC
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Brain tumor patients find new hope for better sleep
Symptom relief CompletedThis study looked at whether a type of talk therapy called cognitive behavioral therapy for insomnia (CBT-I) can help people with brain tumors who have trouble sleeping. The study included 70 adults with various brain tumors who also had insomnia. The goal was to see if the thera…
Phase: PHASE2 • Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated May 26, 2026 03:12 UTC
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Can a phone app ease depression in new moms? large study says maybe.
Symptom relief CompletedThis study tested a mobile program called "Mamma Mia" to see if it helps pregnant women and new mothers feel better emotionally. Over 1,900 women joined the study during early pregnancy. The program provided skills and information on topics like stress, anxiety, and well-being. R…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated May 26, 2026 03:11 UTC
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VR goggles soothe scared kids at the doctor
Symptom relief CompletedThis study tested if using virtual reality (VR) can reduce anxiety in children aged 6-15 during medical procedures like blood draws. Researchers measured heart rate, blood pressure, and fear levels before and after VR. They also looked at how VR affected parents' anxiety and nurs…
Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated May 26, 2026 03:10 UTC
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Talking it out: new therapy eases brain cancer distress
Symptom relief CompletedThis study tested a counseling program called CALM (Managing Cancer and Living Meaningfully) for people with malignant brain cancer. The goal was to see if it's practical and helpful for reducing distress like depression and anxiety about death. 60 participants were offered eithe…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated May 26, 2026 03:09 UTC
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Virtual reality boosts arm recovery in chronic stroke patients
Symptom relief CompletedThis study tested whether using an immersive virtual reality (VR) headset along with practice of real-world arm tasks could improve arm movement in people who had a stroke at least six months earlier. Thirteen adults with limited arm motion took part. Researchers measured arm act…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated May 26, 2026 02:51 UTC
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Weighted blankets may soothe ICU delirium
Symptom relief CompletedThis study looked at whether weighted blankets can help prevent or reduce delirium in adult ICU patients. Delirium is a state of confusion that can happen during a hospital stay. 49 patients, along with their nurses and family members, shared their experiences using the blanket. …
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated May 22, 2026 13:50 UTC
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Can a home exercise program help men on prostate cancer hormone therapy?
Symptom relief CompletedThis study tested whether a remote exercise training program is practical for medically underserved men receiving hormone therapy (ADT) for prostate cancer. Twenty-seven participants were enrolled to see if they would stick with the program and complete assessments. The goal was …
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated May 18, 2026 12:03 UTC
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Teachers' Follow-Through under the microscope: can classroom programs stick?
Knowledge-focused CompletedThis study followed 52 teachers and 72 students to see if teachers continued using a program called BEST in CLASS one year after training. The program helps manage student behavior and improve social skills. Researchers measured how closely teachers stuck to the program and how s…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated May 26, 2026 03:21 UTC
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E-Cig study reveals nicotine delivery differences
Knowledge-focused CompletedThis study looked at how different nicotine levels in e-cigarettes affect nicotine delivery and smoking behavior. Thirty-three healthy smokers aged 18-55 used e-cigarettes with constant device settings but different e-liquid strengths. Researchers measured nicotine in the blood, …
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated May 26, 2026 03:17 UTC
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School water program aims to quench Kids' thirst
Knowledge-focused CompletedThis study tested a program in elementary schools to encourage kids to drink more water. Researchers worked with school staff and students to make hydration easier. They measured how well the program worked and if it improved water bottle use and health markers like cavities and …
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated May 26, 2026 03:15 UTC
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Can a telehealth program help brain tumor patients think clearer? pilot study says maybe
Knowledge-focused CompletedThis study tested whether a telehealth program called C-SMART is practical and well-liked by people with primary brain tumors who have mild memory or thinking problems. Researchers enrolled 32 participants (18 patients and 14 caregivers) to see if they could complete the program …
Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated May 26, 2026 03:13 UTC
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E-Cig flavor ban study reveals surprising smoking shifts
Knowledge-focused CompletedThis study enrolled 71 African American menthol smokers to see how limiting e-cigarette flavors (like menthol or tobacco) changes their smoking habits, toxin exposure, and addiction risk. Participants used different flavored e-cigarettes while researchers tracked cigarette use, c…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated May 26, 2026 03:10 UTC
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New rideshare training boosts independence for autistic adults
Knowledge-focused CompletedThis study tested a rideshare training program for autistic adults ages 18 and older. The goal was to see if the training was acceptable and helped participants use rideshare services more independently and safely. 13 people took part, and researchers measured how well the progra…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated May 26, 2026 03:09 UTC
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Flavor factor: do E-Cig tastes hook smokers more?
Knowledge-focused CompletedThis study tested whether different e-cigarette flavors and nicotine strengths change how much smokers want to use them. 32 adult smokers compared tobacco and menthol e-cigarettes with their own brand cigarettes. Researchers measured how much they'd pay and how price changes affe…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated May 26, 2026 03:05 UTC
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Stress and smoking: new study explores racial differences
Knowledge-focused CompletedThis study looked at how stress affects smoking in African American and white men. Researchers measured stress responses using a psychological test and tracked daily cortisol patterns. The goal was to understand racial differences in stress and smoking behaviors. 95 male smokers …
Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated May 22, 2026 14:04 UTC
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Vaping alcohol: can it fool a breathalyzer?
Knowledge-focused CompletedThis study looked at whether using e-cigarettes that contain alcohol (ethanol) can change the results of breath, blood, and field sobriety tests. Twelve adults who use e-cigarettes and drink alcohol took part. Researchers measured alcohol levels and sobriety over six hours to see…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated May 22, 2026 14:01 UTC
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Study lays groundwork for future LGMD treatments
Knowledge-focused CompletedThis study involved 116 people with Limb Girdle Muscular Dystrophy (LGMD), a group of rare genetic disorders causing progressive shoulder and hip muscle weakness. Researchers measured changes in mobility, muscle function, breathing, and daily activities over time. The goal was to…
Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated May 22, 2026 14:01 UTC
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Community ultrasound program aims to improve care for pregnant women with substance use
Knowledge-focused CompletedThis study explored whether offering fetal ultrasound in community settings, along with care navigation and motivational counseling, helps pregnant women with substance use disorder attend prenatal care and substance use treatment. 103 pregnant women between 22-32 weeks gestation…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated May 22, 2026 14:01 UTC
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Richmond study shines light on black Girls' strengths, not just struggles
Knowledge-focused CompletedThis study aimed to understand the quality of life of Black girls aged 12-17 in Richmond, Virginia. Instead of focusing on problems, researchers used surveys and interviews to highlight the girls' strengths and the community resources that support them. The goal was to create a r…
Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC
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Vape study reveals how sweetness and nicotine form change your puffing habits
Knowledge-focused CompletedThis study looked at how different e-cigarette liquids—varying in sweetness and nicotine form—affect nicotine levels in the blood, how people puff, and how they feel. Thirteen healthy adults who use cigarettes, e-cigarettes, or both took part. Researchers measured puff volume, du…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC
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Neighbor-led weight loss chats show promise in underserved communities
Knowledge-focused CompletedThis study looked at whether a weight loss program led by local community members (called House Chat Leaders) could work in a real-world setting. It involved 71 African American adults from Petersburg, VA, who were interested in making healthy lifestyle changes. The goal was to s…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC
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Blanket battle: upper vs. underbody warming in C-Sections
Knowledge-focused CompletedThis study looked at 124 women having planned C-sections to find the best place to put a forced-air warming blanket (like a Bair Hugger) to keep them warm. Half got an upper-body blanket, half got an underbody blanket. The goal was to see which group had a better core body temper…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated May 20, 2026 11:54 UTC
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Small study probes genetic links to Booze-Fueled aggression
Knowledge-focused CompletedThis study looked at how a person's genes might influence their thinking and behavior after drinking alcohol. Nine healthy adults completed tasks measuring aggression after consuming alcohol versus a non-alcoholic drink. The goal was to better understand the cognitive factors beh…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated May 18, 2026 12:08 UTC
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Liver transplant study targets gut chemical to protect hearts
Knowledge-focused CompletedThis study looked at how a chemical called TMAO, made by gut bacteria, affects heart and blood vessel health in people who have had a liver transplant. Researchers measured TMAO levels and checked blood vessel function in 19 adult liver transplant recipients. The goal was to bett…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated May 12, 2026 13:42 UTC