Virginia Commonwealth University

This trial tests whether older adults who had a kidney transplant more than a year ago can safely stop taking mycophenolate mofetil (MMF), a drug that helps prevent rejection but can cause infections, stomach issues, and cancer over time. Researchers will use blood and urine test…

This trial tests whether a gentle electrical earpiece, worn twice daily for two weeks, can reduce brain swelling caused by radiation necrosis. The device stimulates a nerve in the ear to calm inflammation. Forty people with brain tumors who need a laser procedure will be randomly…

This phase 2 trial tests a drug called sacituzumab tirumotecan in people with neuroendocrine prostate cancer, a rare and aggressive form that has progressed after platinum-based chemotherapy. The drug is given by IV infusion three times per 42-day cycle. The study measures how ma…

The SASHA trial is testing whether a single, high-dose radiation treatment delivered directly to the tumor site over one day is safe and effective for women with early-stage breast cancer. The study will enroll 134 women aged 40-85 who have already had a lumpectomy. Researchers w…

This study tests whether a portable, radiation-free ultrasound performed at the bedside can accurately detect brain injuries in children, compared to the standard head CT scan. Researchers will enroll 220 children aged 2-17 who are already scheduled for a head CT due to suspected…

This study aims to improve an existing violence prevention program for high-risk youth by adding content that directly addresses firearm safety. Researchers will work with about 45 teens aged 13-17 to develop and test new materials. The goal is to reduce the risk of intentional f…

This trial tests a program where trained community members, called Colon Health Champions, lead discussions about colorectal cancer risk and screening barriers. The goal is to see if this peer-led approach is feasible and acceptable for adults aged 45 to 75 who are due for routin…

This study tests whether regular breathing exercises can improve symptoms of Postural Tachycardia Syndrome (POTS), a condition that causes dizziness and rapid heartbeat when standing. Twelve adults with POTS will practice breathing exercises daily for four weeks while researchers…

This study will test whether a wearable device called Apollo Neuro is practical and acceptable for autistic children aged 6 to 14 who hurt themselves. The device delivers low-intensity vibrations through the skin. For about a month, 18 children will wear it at least 3 hours a day…

This study will use transcranial Doppler (TCD) ultrasound to measure blood flow in the brains of 100 people who had a stroke and underwent endovascular therapy (clot removal). The goal is to see if TCD readings can predict complications like bleeding or brain swelling in the days…

This study explores whether a younger adult (ages 25-44) can encourage an older family member (ages 45-75) in rural areas to get screened for colorectal cancer. Researchers will first survey 300 people, then run focus groups, and finally test the approach with 15 parent-child pai…

This study is a registry that will collect health information from 1,000 people who carry the gene for hereditary amyloidosis, including those with and without symptoms. Researchers will track who develops the disease and how it progresses, including the need for heart transplant…