Virginia Commonwealth University

This study tests a program called SHIFT2 that helps teens and young adults with type 1 diabetes prepare to move from pediatric to adult medical care. About 109 participants, aged 16-22, and their caregivers will take part. The goal is to see if the program improves blood sugar co…

This study tests whether giving two immunotherapy drugs (decitabine and pembrolizumab) before standard chemotherapy can boost the body's immune attack on HER2-negative breast cancer. About 46 adults with locally advanced disease will receive this short course, then proceed to usu…

This study tested a shorter course of radiation (hypofractionation) for women with breast cancer that has spread to lymph nodes. The goal was to see if this approach reduces long-term side effects like arm swelling (lymphedema) while still controlling cancer. About 137 women part…

This study gives 30 adults with conditions like diabetes, high blood pressure, or obesity free fruits and vegetables for 12 months. Researchers want to see if this improves food security, diet quality, and disease control. Participants are already in a community wellness program …

This study tests whether an anti-inflammatory drug called anakinra can prevent heart failure in people who have had a heart attack. About 84 adults who recently had a severe heart attack will receive the drug to reduce inflammation and protect their heart. The main goal is to see…

This study tests whether remote doctor visits and home monitoring devices help people with chronic conditions like diabetes and high blood pressure manage their health better. About 40 adults already in a wellness program will use a tablet or phone to track their health and talk …

This early-stage study tests two drugs, niraparib and neratinib, together in people with advanced solid tumors or ovarian cancer that no longer responds to platinum chemotherapy. The goal is to find the safest dose and see if the combination can stop the cancer from growing for a…

This study tests whether a newer drug, letermovir, works better and causes fewer side effects than the standard drug valganciclovir for preventing CMV infection in African American kidney transplant recipients. About 30 high-risk patients will take letermovir for 6 months after t…

This study looks at whether taking vitamin D supplements can lessen nerve pain caused by taxane chemotherapy. About 120 people with low vitamin D levels who are starting chemo will be randomly assigned to get vitamin D or standard care. The goal is to see if vitamin D helps reduc…

This study tests whether a small vibrating device worn on the wrist can improve hand movement and feeling in people who had a stroke at least six months ago. The device uses gentle vibrations to boost touch sensation, which may help with grip and dexterity. The main goal is to se…

This study looks at how often antiepileptic drugs (AEDs) and other psychoactive medications are prescribed in US nursing homes, especially for people with dementia, and how this changed around the COVID-19 pandemic. Researchers will analyze data from over 22 million nursing home …

This research study looks at whether community-based programs can reduce youth violence. It involves about 3,390 teens aged 12-17 and their parents in certain communities. The study tests strategies like hospital-based support for injured youth and activities to build positive sk…

This study looks back at the records of 8,000 people who had weight-loss (bariatric) surgery for severe obesity. Researchers want to learn how different surgeries affect weight loss, safety, and health problems linked to obesity. The goal is to use this information to improve car…