University Of Miami

This study looks at whether testosterone replacement therapy is safe for men who have both low-risk prostate cancer and low testosterone, and are under active surveillance. Researchers will track if the cancer gets worse within 12 months. The goal is to see if this treatment can …

This study tests a drug called emapalumab in 5 adults with a rare, fast-worsening lung disease caused by MDA5 antibodies. The drug aims to calm an overactive immune system to improve breathing and reduce the need for extra oxygen. Participants must have worsening lung function an…

This study looks at whether using antibiotic-coated sutures (threads) during surgery for infected hip or knee replacements is as good as or better than standard sutures. About 142 adults with joint infections will take part. The goal is to see if the special sutures reduce the ch…

This pilot study tests whether injecting doxycycline into fluid pockets (seromas) that form after joint replacement surgery can help them go away and not come back. Ten adults with seromas after orthopedic surgery will receive the injection and be followed with ultrasound. The go…

This study tests whether a precise, MRI-guided radiation treatment can control tumors pressing on the spine, potentially eliminating the need for surgery. About 24 adults with solid tumors causing spinal cord compression will receive this therapy. The main goal is to see if this …

This study looks at whether playing active video games can help children and young adults (ages 5-21) with obesity and type 2 diabetes lose weight and lower their blood sugar (HbA1c). Participants will play active video games at home, and researchers will track changes in weight,…

This study tests injecting the chemotherapy drug cisplatin directly into throat cancer tumors that have come back after radiation. About 20 adults will receive the injection before planned surgery. The goal is to see if this approach can shrink or eliminate the tumor, while also …

This study aims to see if offering a blood test (Guardant Shield) along with standard reminders helps more people who are overdue for colon cancer screening actually get screened. About 500 adults aged 45-85 will be randomly assigned to receive either a standard reminder or a sta…

This study looks at whether 12 weeks of Transcendental Meditation can improve stress, mood, and blood pressure in post-menopausal women who are at risk for hypertension. Sixty women will be randomly assigned to either a meditation program or a health education group. The goal is …

This study looks at whether giving women a single dose of antibiotics during a clinic procedure for stress urinary incontinence (urine leakage) can lower their chance of getting a urinary tract infection (UTI) afterward. About 150 women will be randomly assigned to receive either…

This study tests a program called PrEP & Soccer, run through CVS pharmacies, to help men learn about HIV prevention pills (PrEP) and attend their first appointment. About 800 men aged 18-54 will take part. The program uses soccer-themed materials to raise awareness and make it ea…

This study will see if using a device called the Alexis wound retractor during hip replacement surgery leads to better wound healing and fewer infections compared to not using it. About 202 adults having hip replacement will take part. Researchers will check wound healing, scarri…

This study tests whether a remote stress management program (R-CBSM) can help women aged 50 and older who have finished breast cancer treatment feel less distressed and potentially slow aging caused by cancer and stress. Participants will join group video calls to learn relaxatio…

This study aims to see if a special online program combining mindfulness and music therapy can help people feel better during stem cell transplant recovery. About 165 adults with blood cancers like leukemia or lymphoma will take part. The program is designed to improve quality of…

This study tests a stepped-care version of Parent-Child Interaction Therapy (PCIT) for children aged 2 to 7 who have a mild to moderate traumatic brain injury (TBI) and behavior problems. Researchers will work with 20 parent-child pairs to see if the therapy reduces disruptive be…

This study tests whether cetirizine (Zyrtec) or diphenhydramine (Benadryl) is better tolerated by multiple sclerosis patients before their infusion therapy. About 60 adults with MS will receive one of the two medicines and report sleepiness and fatigue. The goal is to find a pre-…

This study compares two methods to control pain after total knee replacement: a long-acting painkiller (Zynrelef) injected into the knee during surgery versus a standard nerve block. The goal is to see which approach reduces the need for opioid painkillers in the first 72 hours a…

This study is testing a new web-based program designed to help people with pancreatic cancer reduce stress and manage symptoms like pain, fatigue, and sleep problems. Researchers will enroll 60 adults who speak English or Spanish to see if the program is easy to use and helpful. …

This study looks at how well steroid injections work for people with back pain that travels down the leg (sciatica). Researchers will test different doses and two types of steroids to find the best way to reduce pain and improve daily function. The study involves 150 adults who h…

This study tests whether adding sodium hyaluronate (a moisturizer found in artificial tears) to autologous serum eye drops provides better relief for people with moderate-to-severe dry eye disease. Each of the 20 participants will use the new mixture in one eye and the standard s…

This study will test if a special laser (1726nm) can safely shrink or remove small bumps that appear on the face in people with frontal fibrosing alopecia, a type of hair loss. Ten adults with these facial bumps will receive the laser treatment. Doctors will measure changes in bu…

This study looks at how a short, home-based high-intensity workout changes steroid hormone levels in men with low-grade prostate cancer who are on active surveillance. About 49 men will do one supervised bodyweight HIIT session and provide saliva samples. The goal is to understan…

This study looks at how changes in oxygen levels affect the heart's electrical signals in 70 people, both those who need extra oxygen and those who don't. Researchers will measure heart rate variability and other ECG readings to understand the connection. The goal is to learn mor…

This study tests whether AI-generated messages about alcohol and cancer risk can change how cancer survivors think about drinking and motivate them to cut back. About 850 adults who have had certain cancers and currently drink alcohol will receive either gain- or loss-framed mess…

This study tests whether a personalized AI coach that adapts to your real-time performance can help you cycle harder during a 20-minute time trial. Researchers will compare the AI coach to simple motivational phrases and to no coaching at all. The study involves 120 recreationall…