University Of Miami

This study tests whether liraglutide, a medication that reduces fat and promotes weight loss, can shrink the fat deposits around the heart and help stabilize atrial fibrillation (AF) in people who have had a catheter ablation. About 60 adults with AF and a BMI of 27 or higher wil…

This study tests whether using MRI scans to guide higher doses of radiation to the exact spot where prostate cancer has returned after surgery can better lower PSA levels. It involves 37 men whose PSA rose after prostate removal. The goal is to see if this targeted approach impro…

This study compares two radiation therapy schedules for prostate cancer: a shorter course of 5 sessions versus a standard course of 26 sessions. The goal is to see if the shorter treatment is just as effective at controlling cancer over four years. The trial involves 161 men with…

This study offered an experimental treatment using donor stem cells given through an IV to people who had a recent (within 9 days) ischemic stroke. The goal was to see if the stem cells could help the brain heal and improve recovery. It was available to adults aged 18 to 80 with …

This study looks at whether giving a single high dose of vitamin D to patients with low levels before hip or knee replacement surgery can lower the chance of problems like infection. About 200 adults with osteoarthritis and low vitamin D will take part. Researchers will track inf…

This study compares two drug combinations for people newly diagnosed with multiple myeloma, a type of blood cancer. About 310 participants will receive either a standard three-drug regimen (carfilzomib, lenalidomide, dexamethasone) or that same regimen plus daratumumab. The goal …

This study tests whether giving an extra-high dose of radiation to the most aggressive parts of prostate tumors (seen on MRI) can improve cancer control and reduce side effects. About 164 men with prostate cancer will receive either this boost plus standard radiation or standard …

This study screens people for H. pylori, a stomach infection that can lead to chronic inflammation, ulcers, and even stomach cancer. Those who test positive receive treatment to wipe out the bacteria. The goal is to prevent these serious stomach problems. About 75 participants fr…

This study screens 500 adults in South Florida for H. pylori, a stomach infection that can lead to chronic inflammation, ulcers, and even stomach cancer. People who test positive get free treatment right away. The goal is to catch and treat the infection early to prevent serious …

This study looks at the best ways to prevent anxiety and depression in older Latino adults (age 60+) who have mild symptoms but not a full disorder. About 240 participants will join either a health promotion program or a healthy lifestyles education class. Researchers will track …

This study compares two procedures—prostate artery embolization (PAE) and holmium laser enucleation (HoLEP)—to see which better relieves symptoms of an enlarged prostate in men aged 50 and older with glands over 80 grams. Researchers will measure symptom improvement, hospital sta…

This study tests a web-based program called ORCHID designed to improve mental health and help women with HIV stay in care. It involves 30 aging women of color who also have HPV. Participants learn skills to build positive emotions and resilience through 8 online sessions.

This study tests if cyproheptadine, a medicine that boosts appetite, can improve eating habits in children aged 2 to 6 with pediatric feeding disorders. Researchers will measure changes in eating behavior, food variety, and weight over time. The goal is to find a safe, simple way…

This study tests a program that combines mindfulness and music therapy, delivered through an app or website, to help people who are getting a stem cell transplant feel better and have a higher quality of life. About 60 adults with certain blood cancers will try the program during…

This study tests whether a virtual reality (VR) program can help Black women cope with stress and improve heart health. About 60 Black women with high blood pressure will use VR and report changes in stress, sleep, and blood pressure. The goal is to see if VR is a practical and h…

This study looks at whether a mobile app called Horizons can help adults who have chronic graft-versus-host disease after a stem cell transplant. About 20 people will use the app and answer surveys to see if it is practical and helpful. The goal is to improve their quality of lif…

This study aimed to see if practicing mindfulness breathing exercises could improve health and quality of life in adults with spinal cord injury. Researchers planned to measure heart rate, blood pressure, and metabolism changes. However, the study was withdrawn before enrolling a…

This study tests whether injecting platelet-rich plasma (PRP) into the vulva and vagina can ease menopause-like symptoms in breast cancer survivors. About 18 women who have had breast cancer and have low vaginal health scores will receive PRP injections. The goal is to see if sym…

This study tests whether a 1726nm laser (AviClear) can safely reduce painful bumps and abscesses in people with hidradenitis suppurativa (HS). Eight adults with mild-to-moderate HS will receive laser treatment on affected areas like armpits or groin. The main goal is to see if at…

This study looks at whether a special nutrition plan can help manage pain in people with spinal cord injury (SCI). Thirty adults with chronic pain will follow a diet program for 4 months. Researchers will measure changes in pain levels using standard pain scales to see if the die…

This study looks at whether adding an inhaled corticosteroid (ICS) for 4 weeks to the usual COPD treatment (LABA/LAMA) can improve how well the blood vessels in the lungs work. Researchers will measure blood vessel response in 30 adults with COPD, ages 40-80, who have smoked in t…

This study looks at whether a specially designed exercise program can improve strength, endurance, and quality of life for adults with hidradenitis suppurativa (HS), a chronic skin condition that causes painful boils. Researchers will measure changes in physical function and dail…

This study is testing a program called U-PEACE for high school students who are struggling with emotions like anxiety and depression, as well as schoolwork. About 72 teens aged 13 to 18 will take part to see if the program helps them feel better and do better in school. Researche…

This study looks at whether a group-based program called Horizons can help adults with chronic graft-versus-host disease (cGVHD) improve their quality of life and coping skills. About 20 people who had a stem cell transplant and now have moderate to severe cGVHD will take part. T…

This study is collecting samples and data from 610 people with ALS and related disorders, as well as healthy volunteers. The goal is to track natural changes in biological markers over time, which will help researchers design better future clinical trials. Participants do not rec…

This study aims to learn more about ALS and similar diseases like frontotemporal dementia and hereditary spastic paraplegia. Researchers will look at participants' symptoms, genetic information, and biological markers to find connections. The goal is to better understand these co…

This study looks at blood samples from 400 people, both with and without HIV, who use or don't use opioids. The goal is to understand how opioids change the body's immune response to the flu vaccine. Researchers will measure antibody levels and immune cell activity to see if opio…

This study looks at how feeling fear in virtual reality (VR) changes a person's ability to empathize with others. About 110 college students aged 18-25 will watch scary VR videos and report their empathy and anxiety levels, while their heart rate is measured. The goal is to under…

This study looks at whether a simple blood test that tracks cancer DNA (ctDNA) can help doctors decide when to switch treatments for people with stage IV breast cancer. The goal is to see if changing therapy earlier, based on the blood test, can keep the cancer under control long…

This study looks at blood samples from 400 people with and without HIV to understand how aging and HIV infection change the body's immune response to the flu vaccine. Researchers will measure antibody levels and immune cell types to see who responds well to the vaccine and who do…

This study looks at people with early ALS who still have some body areas unaffected. Researchers want to find the very first signs of the disease spreading. About 100 adults with ALS and healthy controls will be followed over time. No treatment is tested; the goal is to better un…

This study looks at whether a friendly robot can be used to teach children with asthma how to manage their condition. Researchers will work with 120 children and their parents to see if the robot is easy to use and if families like it. The goal is to find new ways to make asthma …

This study looks at the bacteria and fungi found in urine and kidney tissue from people with calcium oxalate kidney stones or renal cell carcinoma (a type of kidney cancer), as well as healthy volunteers. The goal is to see if certain microbes are linked to these conditions. Abou…

This study gathers information from 1,200 women with complicated twin pregnancies (twins sharing a placenta) to learn about their health and their babies' health. Researchers will track issues like early delivery and infant survival. The goal is to improve future care, not to tes…