University Of Manitoba

This study tests whether a blood thinner called heparin can help people hospitalized with pneumonia avoid serious complications like needing a breathing machine or intensive care. About 4000 adults will be randomly assigned to receive either heparin or standard care. The goal is …

This study tests whether a special smartphone app (VIEWER) can help people with advanced chronic kidney disease (stage 5) or end-stage kidney disease stay healthier at home and avoid emergency room visits or hospital stays. About 340 adults will be split into two groups: one gets…

This study tests whether people with chronic kidney disease can safely eat fruits and vegetables with higher potassium instead of restricting them. Thirty adults with moderate-to-severe kidney disease will try both diets in random order, with home delivery of produce. Researchers…

This study looks at whether a procedure called middle meningeal artery (MMA) embolization can lower the chance that a subdural hematoma (a type of brain bleed) will come back. About 1000 people with this condition will be enrolled across Canada. The procedure aims to block the bl…

This study tests if Dialectical Behavioral Therapy (DBT), which teaches mindfulness and coping skills, can help teens aged 14-17 with obesity and mild depression improve their quality of life and manage weight to prevent type 2 diabetes. Participants are randomly assigned to life…

This study tests a gel called PluroGel on burn wounds to see if it helps them heal better than standard dressings. About 20 adults with similar burns on both arms or legs will have one limb treated with PluroGel and the other with standard care. The goal is to see if PluroGel red…

This study tests a 4-week online course that teaches people how to manage parasomnias—unwanted sleep events like sleep terrors, sleepwalking, and nightmares. The course provides education and self-management guidance. Researchers will measure if it reduces how often these events …

This study tests whether a special laser can make burn scars less visible, softer, and more comfortable. Six adults with 6- to 12-month-old burn scars on their trunk or limbs will receive laser treatments. The goal is to see if the laser helps the scar blend in better with normal…

This study tests whether using a virtual reality (VR) headset with a guided meditation program can reduce pain, anxiety, and distress in men during a vasectomy. About 90 adult men will be randomly assigned to either use VR during the procedure or receive standard care. Researcher…

This study tests a special video game controller adapter designed for children aged 7 to 17 who have one hand or arm difference. The goal is to see if the adapter makes gaming easier and more fun. Participants will try the adapter in the lab and at home for one week, then share t…

This study tests a gel called Plurogel against standard burn dressings in people with partial thickness burns on the face or one limb. The goal is to see if the gel helps burns heal faster, reduces pain, and lowers the need for skin grafts. About 25 adults will take part, and the…

This study tests whether tranexamic acid, a medicine that helps blood clots stay in place, can reduce bleeding in people with myelodysplastic syndromes or acute myeloid leukemia who are on chemotherapy. About 75 adults with low platelet counts will be randomly assigned to receive…

This study compares two drugs used to control bleeding during skin graft surgery for burn injuries. The standard drug, epinephrine, can sometimes cause unwanted changes in heart rate and blood pressure. Researchers want to see if phenylephrine works just as well to reduce blood l…

This study tests whether different types of mild electrical brain stimulation, combined with thinking exercises, can improve memory and daily function in people with dementia. Two hundred participants will try several stimulation patterns over four-week sessions, with breaks in b…

This study tests if different types of gentle electrical brain stimulation, combined with thinking exercises, can improve memory and thinking in people with dementia. About 100 older adults with mild to moderate dementia will receive either real or fake stimulation to find the be…

This study looks at whether a virtual reality (VR) program can help reduce anxiety in adults preparing for cancer surgery. Researchers will enroll 20 patients to test if the VR approach is practical and well-liked. The goal is to see if using VR before surgery can make patients f…

This study compares two types of anesthesia—spinal and epidural—for people having liver surgery. The goal is to see if spinal anesthesia leads to better blood pressure control, less need for IV fluids, and similar pain relief, helping patients recover faster. About 128 adults und…

This study tests a group mental health program delivered by phone or video for adults 55 and older who feel lonely, isolated, or have anxiety or depression. About 128 participants across four Canadian provinces will either join the program or continue their usual community activi…

This study tests whether a gentle, non-invasive brain stimulation technique called tDCS can improve thinking and memory in people with Parkinson's disease who have mild cognitive problems. About 36 participants will receive either real or fake stimulation to see if it helps resto…

This study tests whether a handheld canister of nitrous oxide (laughing gas) can help control pain and anxiety during burn dressing changes. Thirty adults with burns covering 5-20% of their body will try both the gas and standard care to see which works better. The goal is to fin…

This study tests a new wearable device that uses light to measure how well the brain controls its blood flow. Researchers will test the device on 250 healthy volunteers to see if it works and to learn how age and sex affect brain blood flow regulation. The goal is to create a por…

This study tests a new, non-invasive way to measure brain waves linked to anxiety using a device placed in the outer ear canal. Researchers will give healthy volunteers two different drugs that lower these brain waves to see if the ear device can detect the changes. If successful…

This study aims to create a better understanding of play for children with physical disabilities. Researchers will interview families, then give children Lego robots to build and play with for a few weeks. The goal is to develop a complete model of play that helps experts identif…

This study looks at why many people who survive a serious illness in the ICU develop lasting muscle weakness. Researchers will test the heart and blood flow of 50 former ICU patients during exercise. The goal is to better understand the problem, not to test a new treatment.

This study is gathering information from 100 adults aged 30 and older who are members of the Wellness Institute in Manitoba. Researchers will measure things like fitness, diet, sleep, stress, and overall health to understand how lifestyle and gym use relate to healthy aging. No t…

This study follows about 225 children whose mothers had type 1 diabetes during pregnancy. Researchers will check the kids' thinking skills and look for links to autism. The goal is to learn how diabetes during pregnancy may affect a child's brain development over time.

This study is looking for genetic markers that may predict which children and youth (ages 6-24) with depression, anxiety, or OCD will experience behavioral activation—a side effect of SSRI antidepressants like Prozac or Zoloft. Researchers will compare the DNA of 160 participants…

This study looks at whether a simple genetic test can help doctors choose safer and more effective medications for people with mental health conditions. About 200 adults in Manitoba will provide a saliva sample for testing, and researchers will track how useful and practical the …

This study looks at how a gentle, non-invasive brain stimulation method called HD-tDCS changes the way different brain regions talk to each other. Researchers will measure brain activity and blood flow in 100 healthy adults before and after stimulation. The goal is to better unde…