University Of Manitoba
Clinical trials sponsored by University Of Manitoba, explained in plain language.
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Canola oil may help tame metabolic syndrome risks
Disease control CompletedThis study looked at whether replacing typical cooking fats with canola oil for 12 weeks can improve cholesterol, blood vessel function, and other heart-related factors in people with metabolic syndrome. 80 adults aged 20-75 with high LDL cholesterol and at least two other metabo…
Phase: NA • Sponsor: University of Manitoba • Aim: Disease control
Last updated May 26, 2026 05:32 UTC
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New hospital policy cuts blood transfusions in major surgeries
Disease control CompletedThis study tested whether a hospital policy of using a medicine called tranexamic acid could reduce the need for blood transfusions in adults undergoing major non-cardiac surgery. Over 8,000 patients took part across multiple hospitals. The goal was to see if the policy safely lo…
Phase: PHASE4 • Sponsor: University of Manitoba • Aim: Disease control
Last updated May 26, 2026 05:31 UTC
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Pedaling while dialyzing: exercise may shield hearts of kidney patients
Disease control CompletedThis study looked at whether a 12-week cycling program during hemodialysis sessions can reduce heart muscle stress (called stunning) in adults with end-stage kidney disease. 111 participants either cycled during dialysis or received standard care. The main goal was to see changes…
Phase: NA • Sponsor: University of Manitoba • Aim: Disease control
Last updated May 26, 2026 05:25 UTC
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Pea protein vs. whey: which saves more muscle during dieting?
Disease control CompletedThis study looked at whether pea protein can help people with obesity keep their muscle mass while losing weight. About 60 adults aged 30 to 50 took part. Researchers compared the effects of pea protein and whey protein on muscle size and strength.
Phase: NA • Sponsor: University of Manitoba • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
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New CT scan may sharply improve bleeding detection after stroke
Diagnosis CompletedThis study looked at whether a special type of CT scan (dual-energy CT) can more accurately tell the difference between bleeding and harmless contrast dye after stroke treatment. About 189 adults who had a stroke and received clot-busting drugs or a clot-removal procedure took pa…
Phase: NA • Sponsor: University of Manitoba • Aim: Diagnosis
Last updated May 18, 2026 12:08 UTC
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Can a writing therapy delivered online in groups help ease PTSD?
Symptom relief CompletedThis study tested if Written Exposure Therapy (WET) can be given virtually in a group setting to help military and police with PTSD. 29 people took part to see if the treatment was acceptable and if it reduced trauma symptoms. The goal was to understand if this approach is feasib…
Sponsor: University of Manitoba • Aim: Symptom relief
Last updated May 26, 2026 05:32 UTC
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New workshop aims to help chronic pain patients taper off opioids safely
Symptom relief CompletedThis study tested a one-day educational workshop for adults with chronic non-cancer pain who take high doses of opioids. The workshop, led by a team of doctors, pharmacists, and psychologists, taught about opioid risks and a pain management technique called Acceptance and Commitm…
Phase: NA • Sponsor: University of Manitoba • Aim: Symptom relief
Last updated May 26, 2026 05:31 UTC
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Talking therapy eases anxiety for new and expecting moms
Symptom relief CompletedThis study tested a 6-week group therapy program for pregnant women and new mothers struggling with anxiety. 72 participants learned coping skills like facing fears and managing worries. The therapy was delivered online and aimed to reduce stress and anxiety, with benefits lastin…
Phase: NA • Sponsor: University of Manitoba • Aim: Symptom relief
Last updated May 26, 2026 05:30 UTC
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VR headsets take on phantom pain after leg amputation
Symptom relief CompletedThis study looked at whether a virtual reality (VR) program is a practical and acceptable way to treat phantom limb pain in people who just had a leg amputated. Twenty participants tried the VR program daily for about 17 sessions in the hospital, at home, or in therapy clinics. R…
Sponsor: University of Manitoba • Aim: Symptom relief
Last updated May 26, 2026 05:29 UTC
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Could a smaller steroid dose be just as good for kids with croup?
Symptom relief CompletedThis study looked at whether a lower dose of the steroid dexamethasone (0.15 mg/kg) works as well as the standard dose (0.6 mg/kg) for treating croup in children. Croup causes swelling in the throat and makes it hard to breathe. The goal was to see if a lower dose could reduce si…
Phase: PHASE3 • Sponsor: University of Manitoba • Aim: Symptom relief
Last updated May 26, 2026 05:28 UTC
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Exercise eases dialysis burden: new study shows promise
Symptom relief CompletedThis study looked at whether a 26-week exercise program can reduce symptoms and improve quality of life for people on long-term hemodialysis. 133 participants were randomly assigned to either the exercise program or usual care. The main goal was to see if exercise lessened sympto…
Phase: NA • Sponsor: University of Manitoba • Aim: Symptom relief
Last updated May 26, 2026 05:27 UTC
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Glue vs. stitches: new study tests faster circumcision recovery
Symptom relief CompletedThis study compared using skin glue (2-OCA) with a few stitches to the usual method of continuous stitches for closing wounds after adult circumcision. Twenty men took part, and researchers measured pain, healing, appearance, and complications. The goal was to see if the glue met…
Phase: NA • Sponsor: University of Manitoba • Aim: Symptom relief
Last updated May 26, 2026 05:21 UTC
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Hope in a classroom: new class aims to cut suicide risk after an attempt
Symptom relief CompletedThis study tested a 12-week class called Living with Hope for people who had recently attempted suicide. The class taught coping skills based on cognitive behavioral therapy (CBT). Researchers measured changes in suicidal thoughts, hopelessness, and depression over time. The goal…
Sponsor: University of Manitoba • Aim: Symptom relief
Last updated May 22, 2026 14:03 UTC
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New inhaler may ease pain during awake urology surgeries
Symptom relief CompletedThis pilot study tested whether adding inhaled methoxyflurane (Penthrox) to local anesthetic reduces pain and anxiety during urology procedures like hydrocele repair or testicular biopsy. Forty adult patients were randomly assigned to receive either local anesthetic alone or with…
Phase: PHASE2 • Sponsor: University of Manitoba • Aim: Symptom relief
Last updated May 22, 2026 14:03 UTC
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Video games could be the key to better hand rehab after stroke or spinal injury
Symptom relief CompletedThis study tested a computer game system designed to help adults with stroke or spinal cord injury improve hand and arm movement. Thirty-five participants used special game controllers that work like a computer mouse to play games that require hand dexterity. The goal was to see …
Phase: NA • Sponsor: University of Manitoba • Aim: Symptom relief
Last updated May 22, 2026 14:02 UTC
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Brain training: can CBT classes build PTSD resilience?
Knowledge-focused CompletedThis study looked at whether a 5-session class teaching cognitive behavioral therapy (CBT) skills could increase a brain pattern linked to resilience against PTSD. It involved 30 public safety personnel (like police or firefighters) who were already in a larger study. The goal wa…
Phase: NA • Sponsor: University of Manitoba • Aim: Knowledge-focused
Last updated May 26, 2026 05:35 UTC
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Zapping the brain to boost therapy: small study shows promise
Knowledge-focused CompletedThis study tested whether a gentle, non-invasive brain stimulation technique (HD-tDCS) could boost the effects of cognitive behavioral therapy (CBT) for people with depression, anxiety, or PTSD. Twenty participants received the stimulation alongside their regular therapy. The goa…
Phase: NA • Sponsor: University of Manitoba • Aim: Knowledge-focused
Last updated May 26, 2026 04:36 UTC
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Saskatoon berry study reveals blood sugar impact
Knowledge-focused CompletedThis study measured how dried Saskatoon berries and their powder affect blood sugar levels in 10 healthy adults. Participants ate the berries or a sugar drink, and researchers tracked their blood sugar response. The goal is to provide clear dietary advice for people who want to m…
Phase: NA • Sponsor: University of Manitoba • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC
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Urine test may spot kidney rejection before damage is done
Knowledge-focused CompletedThis study looked at whether checking a substance in urine called CXCL10 can help find kidney transplant rejection earlier than usual. 260 adult kidney transplant patients took part. The goal was to see if early treatment based on this test could help the new kidney work better a…
Phase: PHASE2, PHASE3 • Sponsor: University of Manitoba • Aim: Knowledge-focused
Last updated May 22, 2026 13:51 UTC
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Spinal anesthesia in heart valve surgery: a closer look at blood flow changes
Knowledge-focused CompletedThis study observed 44 adults with severe aortic stenosis or severe mitral regurgitation undergoing valve replacement surgery. Researchers measured how spinal anesthesia changed blood flow and the need for medications to keep the heart stable. The goal was to better understand th…
Sponsor: University of Manitoba • Aim: Knowledge-focused
Last updated May 19, 2026 11:47 UTC