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Pedaling while dialyzing: exercise may shield hearts of kidney patients

NCT ID NCT04877041

Knowledge-focused Sponsor: University of Manitoba Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether a 12-week cycling program during hemodialysis can reduce heart muscle stress (called stunning) in adults with end-stage kidney disease. 111 participants either cycled or rested during their dialysis sessions. Researchers measured heart function with ultrasound and blood tests to see if exercise made a difference.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

111 people

The number who actually took part.

Started

Mar 2023

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults greater than or equal to 18 years old (no upper age limit); who are greater than; 3 months after starting maintenance hemodialysis * No expected change in dialysis modality, elective surgery or relocation outside of study site during the intervention period (16 weeks) * Assessed to be safe and able to exercise by the hemodialysis unit nephrologist * Able to communicate in English and provide written informed consent * Must be dialyzing thrice weekly Exclusion Criteria: * Acute coronary syndrome in the past 3 months * Unstable arrhythmia * Shortness of breath at rest or with minimal activity (NYHA Class 4) * Symptomatic hypoglycemia (\>2x/week in week prior to enrolment) * Participating in clinical intradialytic cycling program in last 3 months (if a clinical program exists)

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Conditions

The condition(s) this trial relates to.

chronic kidney disease end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

End-stage kidney disease Hemodialysis

Contacts and locations

Locations

  • St. Pauls Hospital

    Vancouver, British Columbia, V6Z1Y6, Canada

  • University of Alberta Department of Internal Medicine

    Edmonton, Alberta, T6G 2G3, Canada

  • University of Calgary Cumming School of Medicine Department of Internal Medicine

    Calgary, Alberta, T2N 2T9, Canada

  • University of Manitoba Department of Internal Medicine

    Winnipeg, Manitoba, R3A 1R9, Canada

  • University of South Australia

    Adelaide, South Australia, 5001, Australia

  • Western University

    London, Ontario, N6A5C1, Canada

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