New procedure aims to stop brain bleeds from coming back
NCT ID NCT04923984
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This Canadian study is testing whether blocking a small artery in the brain's lining can prevent chronic subdural hematomas from returning. The procedure, called middle meningeal artery embolization, uses tiny particles or coils to cut off blood flow to the bleeding area. Researchers will follow 1,000 patients to see if this approach reduces the need for repeat surgeries and improves recovery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Embolization procedure (microparticles, liquid embolic agents, or coils) to block the middle meningeal artery
- What this could lead to
- If successful, this procedure could lower the chance that a subdural hematoma comes back, reducing the need for repeat surgeries.
- What could go wrong
- This is an observational study, not a randomized trial, so results may be less definitive. Risks include allergic reaction to the embolic agent or procedural complications.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 1,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2021
- Expected to finish
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Dec 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: \- All patients with subdural hematoma coming to the emergency room or to neurosurgical outpatient clinic. Exclusion Criteria: * If informed consent cannot be obtained from the patient or their substitute decision maker. * Known allergy to liquid embolic agent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Health Sciences centre
RECRUITINGWinnipeg MB, Manitoba, R3A 1R9, Canada
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- Brain bleed breakthrough? new study tests artery blocking to avoid surgery