Thomas Jefferson University
Clinical trials sponsored by Thomas Jefferson University, explained in plain language.
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Meal delivery and telehealth coaching show promise for diabetes management
Disease control CompletedThis study tested whether providing medically tailored meals and nutrition counseling through video calls can improve blood sugar control in adults with poorly controlled type 2 diabetes. About 600 participants received either usual care, tailored meals alone, or meals plus teleh…
Phase: NA • Sponsor: Thomas Jefferson University • Aim: Disease control
Last updated May 01, 2026 15:59 UTC
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New program helps cancer patients kick the habit
Disease control CompletedThis study tested a special smoking cessation program for people with head and neck or lung cancer. The program included counseling, medication, and nicotine replacement to help patients reduce smoking. Researchers wanted to see if cutting down could also change the tumor environ…
Phase: NA • Sponsor: Thomas Jefferson University • Aim: Disease control
Last updated May 01, 2026 15:58 UTC
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Can antioxidant supplements boost brain health in Parkinson's?
Disease control CompletedThis study looked at whether nutritional supplements, specifically N-acetyl cysteine (NAC) given orally and intravenously, could support brain function in people with Parkinson's disease. Fifty-one participants were randomly assigned to receive NAC, standard care, or other oral s…
Phase: NA • Sponsor: Thomas Jefferson University • Aim: Disease control
Last updated Apr 30, 2026 15:51 UTC
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Radioactive beads shrink liver tumors in eye cancer patients
Disease control CompletedThis study tested whether tiny radioactive beads (Y90 microspheres) delivered directly to the liver could shrink tumors in 48 people with advanced eye melanoma that had spread to the liver. The goal was to control the disease and improve survival. The treatment is a one-time proc…
Phase: PHASE2 • Sponsor: Thomas Jefferson University • Aim: Disease control
Last updated Apr 30, 2026 15:48 UTC
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Bubble ultrasound may predict cancer treatment success
Diagnosis CompletedThis study tested whether a special ultrasound using gas microbubbles can predict how bile duct cancer responds to targeted radiation therapy. Sixteen adults with bile duct cancer received the ultrasound before and during treatment. The goal was to see if the ultrasound could hel…
Phase: PHASE2 • Sponsor: Thomas Jefferson University • Aim: Diagnosis
Last updated May 01, 2026 16:00 UTC
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Robot vs hand: can a machine match a Doctor's ultrasound for breast cancer surveillance?
Diagnosis CompletedThis study looked at whether an automated breast ultrasound (ABUS) can be used instead of a handheld ultrasound (HHUS) to screen for breast cancer in women who have had breast reconstruction after a mastectomy. Twelve women who had nipple-sparing or skin-sparing mastectomy with r…
Phase: NA • Sponsor: Thomas Jefferson University • Aim: Diagnosis
Last updated Apr 30, 2026 15:50 UTC
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Sound waves may replace needles for breast cancer pressure checks
Diagnosis CompletedThis early study tested whether a special ultrasound technique (contrast-enhanced ultrasound) can estimate pressure inside breast tumors without needles. 25 women scheduled for breast biopsy took part. The goal was to see if this noninvasive method could match standard pressure m…
Phase: EARLY_PHASE1 • Sponsor: Thomas Jefferson University • Aim: Diagnosis
Last updated Apr 29, 2026 15:03 UTC
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Could a simple ultrasound replace the needle for brain pressure checks?
Diagnosis CompletedThis study tested a new, noninvasive way to measure pressure inside the skull using ultrasound and tiny gas bubbles. Nineteen adults who were already scheduled for a lumbar puncture (spinal tap) to check their brain pressure took part. The goal was to see if the ultrasound method…
Phase: PHASE2 • Sponsor: Thomas Jefferson University • Aim: Diagnosis
Last updated Apr 26, 2026 20:00 UTC
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Aspirin's hidden power: could a simple blood test prevent pregnancy complications?
Prevention CompletedThis study enrolled 130 pregnant women at high risk for preeclampsia to see how aspirin affects their platelet function. Researchers measured blood clotting times and looked at genetic factors that might influence aspirin's effectiveness. The goal is to learn how to personalize a…
Sponsor: Thomas Jefferson University • Aim: Prevention
Last updated May 01, 2026 16:01 UTC
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Custom home workouts boost activity in advanced breast cancer
Symptom relief CompletedThis study tested a tailored, home-based exercise program designed by a cancer exercise specialist for women with metastatic breast cancer who were not very active. The goal was to see if a personalized plan could help them move more and improve their quality of life. Twelve wome…
Phase: NA • Sponsor: Thomas Jefferson University • Aim: Symptom relief
Last updated Apr 30, 2026 15:52 UTC
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Cancer care comes home: new study tests convenience of At-Home infusions
Symptom relief CompletedThis study looked at whether giving a multiple myeloma drug (daratumumab) at home instead of at a cancer center could make treatment easier for patients. Twenty adults with multiple myeloma received their monthly injections at home and filled out surveys about their satisfaction.…
Phase: PHASE4 • Sponsor: Thomas Jefferson University • Aim: Symptom relief
Last updated Apr 29, 2026 15:15 UTC
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Stress and depression linked to liver damage in korean americans with hepatitis b
Knowledge-focused CompletedThis study looked at how factors like chronic stress and depression might make liver disease worse in Korean Americans with long-term hepatitis B infection. Researchers collected health information from 365 participants over time to see how these factors relate to liver damage, c…
Sponsor: Thomas Jefferson University • Aim: Knowledge-focused
Last updated May 01, 2026 15:58 UTC
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Pandemic pregnancy puzzle: new study tracks COVID immunity in moms and babies
Knowledge-focused CompletedThis study followed 105 pregnant women diagnosed with COVID-19 to learn how their immune systems responded and whether that protection passed to their babies. Researchers measured antibodies in mothers and newborns, as well as in breast milk, up to 6 weeks after birth. The goal w…
Sponsor: Thomas Jefferson University • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:52 UTC
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New group care model aims to support moms in opioid recovery and their babies
Knowledge-focused CompletedThis study tested a group well child care program for mothers in treatment for opioid use disorder and their infants. About 49 mother-baby pairs took part, with some receiving group care and others individual care. The goal was to see if group care improves how often families att…
Phase: NA • Sponsor: Thomas Jefferson University • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:50 UTC
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Vaccine shield: study tracks COVID-19 protection passed from mom to baby
Knowledge-focused CompletedThis study followed 150 pregnant or breastfeeding women who received a COVID-19 booster shot. Researchers measured antibody levels in mothers, infants, and breastmilk to understand how well the vaccine protects both mom and baby against COVID-19 variants. The goal was to learn ab…
Sponsor: Thomas Jefferson University • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:49 UTC
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Friendly neighbors may hold key to prostate cancer genetic screening in black men
Knowledge-focused CompletedThis study looked at whether a peer-based health education program could help African American men better understand prostate cancer genetic testing. About 150 men with or without a personal or family history of prostate cancer took part. The program aimed to reduce confusion and…
Phase: NA • Sponsor: Thomas Jefferson University • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:05 UTC
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Heart surgery patients breathe easier with mechanical ventilation during ICU transport, study finds
Knowledge-focused CompletedThis study looked at 78 adults who had heart surgery and needed a breathing tube afterward. Researchers compared using a machine (mechanical ventilator) versus a hand-held bag (manual ventilation) to help patients breathe while being moved to the intensive care unit. The goal was…
Phase: NA • Sponsor: Thomas Jefferson University • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:04 UTC
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Discarded tumor tissue yields clues for future cancer treatments
Knowledge-focused CompletedThis study looked at tumor tissue and blood samples from 141 adults with glioblastoma or other solid tumors. The goal was to understand how many cells can be collected and how well they survive, which may help doctors design better treatments in the future. No new therapies were …
Sponsor: Thomas Jefferson University • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:02 UTC
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New app helps prostate cancer patients decide on genetic testing
Knowledge-focused CompletedThis study tested a mobile-friendly tool that helps men with prostate cancer learn about genetic testing and decide if they want it. Researchers compared the tool to traditional genetic counseling. The goal was to see if the tool could help patients make informed choices. The stu…
Phase: NA • Sponsor: Thomas Jefferson University • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:02 UTC