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Parkinson's patients try antioxidant supplements to boost brain health

NCT ID NCT02445651

First seen Jan 11, 2026 · Last updated Jun 12, 2026 · Updated 27 times

Summary

This study looked at whether nutritional supplements, specifically N-acetyl cysteine (NAC) given orally and intravenously, could support brain function in people with Parkinson's disease. The researchers measured dopamine activity and markers of inflammation in the brain using special scans. 51 participants were randomly assigned to receive NAC, standard care, or other oral supplements, though the oral supplement group was later dropped from analysis.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

Conditions

The condition(s) this trial relates to.

brain disorder central nervous system disorder movement disorder nervous system disorder neurodegenerative disease Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.