Thomas Jefferson University
Clinical trials sponsored by Thomas Jefferson University, explained in plain language.
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New radiation approach aims to control aggressive brain tumors
Disease control TerminatedThis early-phase study tests whether giving higher doses of radiation, guided by special PET/MRI scans, is safe for people with high-risk meningiomas (aggressive or returning brain tumors). About 24 adults with recurrent or partially removed grade 2 or any grade 3 meningioma will…
Phase: PHASE1 • Sponsor: Thomas Jefferson University • Aim: Disease control
Last updated May 01, 2026 16:00 UTC
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Biopsy needle showdown: which tool gets the best tissue samples?
Diagnosis TerminatedThis study was designed to compare two types of needles used to take tissue samples from solid masses in the pancreas and digestive tract. The goal was to see which needle provides more accurate diagnoses. However, the study was withdrawn before any participants were enrolled.
Phase: NA • Sponsor: Thomas Jefferson University • Aim: Diagnosis
Last updated Apr 29, 2026 15:05 UTC
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MS patients test antioxidant supplement for brain boost
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether N-acetyl cysteine (NAC), an antioxidant supplement, can help support brain function in people with multiple sclerosis (MS). Researchers will use special PET-MRI scans to measure brain activity and inflammation. About 55 adults with MS who are not plann…
Phase: NA • Sponsor: Thomas Jefferson University • Aim: Symptom relief
Last updated May 01, 2026 15:58 UTC
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New study tests better pain control for broken ribs
Symptom relief OngoingThis study compares three ways to manage pain from rib fractures in adults aged 55 and older. Participants receive either a nerve block, a lidocaine drip, or standard pain medicines. The goal is to see which approach reduces opioid use and improves breathing.
Phase: PHASE4 • Sponsor: Thomas Jefferson University • Aim: Symptom relief
Last updated May 01, 2026 15:57 UTC
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Sleep study for head and neck cancer patients withdrawn before starting
Knowledge-focused TerminatedThis study was designed to track sleep quality in head and neck cancer patients before, during, and after surgery. Researchers planned to measure factors like time to fall asleep, nighttime awakenings, and overall sleep quality. The goal was to understand how treatment affects sl…
Sponsor: Thomas Jefferson University • Aim: Knowledge-focused
Last updated May 01, 2026 15:56 UTC
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New wearable could predict opioid breathing emergencies
Knowledge-focused ENROLLING_BY_INVITATIONThis study tests a wearable device that listens to breathing sounds to detect and predict breathing problems caused by opioid painkillers in 120 post-surgery patients. The device aims to alert doctors early if a patient's breathing becomes dangerously slow or stops. The goal is t…
Phase: NA • Sponsor: Thomas Jefferson University • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:51 UTC
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Virtual board aims to boost prostate cancer genetic Know-How
Knowledge-focused OngoingThis study looks at whether a web-based virtual genetics board helps healthcare providers discuss prostate cancer genetics, precision treatments, and screening recommendations. About 118 providers from academic, community, and veteran affairs settings will take part in interviews…
Sponsor: Thomas Jefferson University • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:04 UTC
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New study aims to boost colorectal cancer screening in underserved communities
Knowledge-focused TerminatedThis study looks at what helps or prevents people from getting screened for colorectal cancer, focusing on African American, Latinx, and Chinese communities. Researchers will talk with community members to learn about their knowledge, beliefs, and cultural factors. The goal is to…
Sponsor: Thomas Jefferson University • Aim: Knowledge-focused
Last updated Apr 28, 2026 13:02 UTC