Peking University Third Hospital

This study tests whether giving two drugs (toripalimab and 9MW2821) before surgery can improve outcomes for people with a type of urinary tract cancer. About 40 adults with localized cancer will be randomly assigned to receive the drug combination followed by surgery, or surgery …

This early study tests a personalized treatment called YS247 for people with a specific type of ovarian cancer (HRD-negative) that didn't fully respond to standard therapy. The treatment uses the patient's own immune cells, trained to recognize their tumor's unique markers, to tr…

This study tests two drugs, zeprumetostat and fuzuloparib, together in 30 adults with advanced or recurrent ovarian cancer that has come back after platinum treatment. The goal is to see if the combination can shrink tumors and control the disease. Participants must have a specif…

This study tests whether injecting a woman's own platelet-rich plasma (PRP) into her ovaries can improve egg production for IVF. It includes 142 women with poor ovarian response or early ovarian failure. The goal is to see if this simple, low-risk procedure increases the number o…

This study tests whether adding Mailuo Shutong Pills to standard wound care helps heal diabetic ulcers faster. The pill is a Chinese herbal medicine already approved for other conditions. About 56 adults with diabetes and a specific tongue diagnosis will take part. The goal is to…

This study tests whether giving a drug that blocks a key inflammatory protein (TNF-alpha) within 6 hours after a cardiac arrest can improve survival and brain recovery. The trial involves 208 adults who remain unconscious after their heartbeat is restored. The goal is to see if c…

This study aims to create an AI-based system that helps people with diabetes spot early warning signs of foot ulcers returning. Researchers will enroll 200 adults with healed diabetic foot ulcers and use a home monitoring tool to track their feet. The goal is to catch recurrences…

This early-phase study tests BCT301, a therapy made from special stem cells turned into immune cells, for people with hard-to-treat autoimmune diseases like lupus and scleroderma. The main goal is to check safety and find the right dose. Only 10 participants will be enrolled.

This study will test a new zirconia ceramic hip joint in 290 people who need a hip replacement. The goal is to see if the joint is safe and works well. Participants will be followed for one year after surgery to check their recovery and joint function.

This study tests a new treatment for women with poor ovarian response, a condition where the ovaries don't produce enough eggs for IVF. Doctors will inject the patient's own cells (from fat or blood) into the ovaries to try to improve egg production and pregnancy rates. The study…

This study tests a new wireless pressure microcatheter to diagnose coronary microvascular dysfunction (CMD) in people with chest pain but no major artery blockages. About 114 adults will undergo the procedure, and results will be compared to heart MRI scans. The goal is to see if…

This study tests a new, non-invasive wearable device that uses electrical signals to monitor how the bladder empties in men with benign prostatic hyperplasia (BPH). Forty participants will wear the device while also taking a standard clinic test to see if the new method is accura…

This study tests a new way to detect early damage in the feet of people with diabetes. By measuring how the skin on the bottom of the foot responds to pressure, researchers hope to identify those at risk for foot ulcers before they develop. The study will include 200 adults with …

This study tests whether a specific probiotic mixture can prevent allergic diseases in breastfed infants who received antibiotics within their first month of life. Researchers will give the probiotics or a placebo to 400 babies and track allergy development, gut bacteria changes,…

This study tests whether a 12-week program focusing on diet, exercise, sleep, and nutrition can prevent or slow early fertility decline in women aged 20-40. About 384 women with early signs of reduced ovarian reserve will be randomly assigned to either the lifestyle program or st…

This study tests whether adding single-leg 20-degree squats to standard physical therapy helps people walk better after anterior cruciate ligament (ACL) reconstruction surgery. About 48 adults aged 18-45 with a recent ACL tear and weak thigh muscles will be enrolled. Researchers …

This study tests whether virtual reality (VR) brain exercises can improve thinking and memory in older adults with cerebral small vessel disease after non-cardiac surgery. About 240 participants will use a VR system with eye-tracking and games before their operation. The goal is …

This study looks at whether losing weight can make psoriasis treatments work better for overweight or obese people with moderate-to-severe plaque psoriasis. About 70 participants will either get standard psoriasis care alone or standard care plus a personalized weight loss plan (…

This study looks at whether adding steroid nasal drops to smell training can improve smell function better than smell training alone in people who lost their sense of smell after an infection. About 100 adults aged 18-65 with confirmed smell loss will participate. The main goal i…

This study tests whether a personalized exercise program created by artificial intelligence can improve knee movement and reduce pain in people with rheumatoid arthritis. 147 adults with mild-to-moderate arthritis will be split into three groups: one using the AI system, one usin…

This study tests whether a traditional Chinese medicine hand-foot soak can reduce nerve pain and skin reactions caused by chemotherapy. 300 adults with solid tumors who have these side effects will use the soak and report their symptoms. The goal is to find a safe, effective way …

This study compares two silver wound dressings—a newer soft silicone foam and a traditional one—to see which heals infected chronic wounds better and costs less. About 40 adults with ulcers will be randomly assigned to one dressing for two weeks. The goal is to find the best opti…

This study compares two ways of giving steroid medicine to people with chronic sinusitis who have lost their sense of smell due to blocked nasal passages. One group will receive steroid drops aimed directly at the smell area, while the other group uses standard steroid sprays. Th…

This study looks at whether special foot exercises can help people with chronic plantar fasciitis (long-term heel pain) move their big toe better and walk more normally. Researchers will measure pain, toe movement, and walking patterns in 34 adults before and after training. The …

This study tests a new digital system that uses wearable sensors and AI to guide knee rehabilitation at home. It includes 160 adults aged 18-50 with ACL tears or patellar knee pain. The goal is to see if this smart system improves knee function and reduces pain better than tradit…

This study looks at whether using a pillow placed behind the shoulder after rotator cuff repair surgery can lower pain and improve sleep. About 126 adults aged 40-70 who are having this surgery will choose whether to use the pillow. Their pain, sleep quality, and shoulder functio…

This study looks at 200 people with Charcot-Marie-Tooth disease (CMT) who have foot problems that make walking hard. Researchers want to see if surgery to fix the foot followed by rehab leads to better walking than physical therapy alone. Participants will be followed for up to t…

This study aims to build an AI-powered early warning system to detect signs of diabetic foot ulcers returning after they have healed. Researchers will follow 200 adults with healed diabetic foot ulcers, using smart technology to create personalized follow-up plans and home care p…

This study will create a comprehensive health management platform for people with early-stage Cardiovascular-Kidney-Metabolic (CKM) syndrome, a condition linking heart disease, kidney problems, and metabolic issues like diabetes. Researchers will enroll 150 adults aged 18-75 who …

This study aims to create a new CT scoring system to better understand how blockages in the nose's smell center relate to loss of smell in people with central compartment atopic disease (CCAD), a type of nasal allergy. Researchers will compare the new method to traditional CT sco…

This study focuses on extremely preterm infants (born before 32 weeks) who have a heart condition called hsPDA, where a blood vessel fails to close after birth. Researchers will collect blood samples and health data to create a model that predicts which babies are at highest risk…