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VR brain games before surgery may shield seniors from memory loss

NCT ID NCT07370844

Symptom relief Sponsor: Peking University Third Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether doing virtual reality (VR) brain exercises for a few days before surgery can help older adults with cerebral small vessel disease avoid confusion or memory problems after their operation. Two hundred forty participants will either receive VR training or standard care. Researchers will measure thinking skills and brain scans before and after surgery to see if the VR group does better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Virtual reality cognitive training device
What this could lead to
If it works, this could offer a simple, drug-free way to protect thinking and memory in older adults after routine surgery.
What could go wrong
This is an early-stage trial with only 240 participants, so results may not apply to everyone. The VR training is short-term and may not produce lasting benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 240 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Feb 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age≥60; 2. Preoperative MRI-confirmed cerebral small vessel disease; 3. Scheduled to undergo non-cardiac, non-craniotomy procedures under general anesthesia; 4. ASA physical status classification: I-III; 5. No use of cognitive-enhancing medications within 3 months prior to surgery; 6. Voluntary participation with signed informed consent Exclusion Criteria: 1. Contraindications to cranial MRI (e.g., cardiac pacemaker, metallic implants, etc.); 2. Intolerance to VR equipment during pre-training adaptation (e.g., dizziness, nausea, vomiting, or other subjective discomfort); 3. Severe visual or auditory impairment; 4. Severe hepatic or renal dysfunction; 5. Pre-existing neuropsychiatric disorders (e.g., schizophrenia, epilepsy, Parkinson's disease, or active delirium); 6. Inability to complete preoperative neuropsychological assessments (e.g., dementia, deaf-mutism, or communication barriers); 7. Use of sedatives, antidepressants, or history of psychoactive substance abuse/alcoholism

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Conditions

The condition(s) this trial relates to.

Cerebral Small Vessel Diseases Emergence Delirium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cerebral small vessel disease Postoperative cognitive function

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    3 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Peking University First Hospital

    Beijing, China

  • Peking University Third Hospital

    Beijing, China

  • Xuanwu Hospital

    Beijing, China

More trials for these conditions

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