Could a shot of your own cells boost fertility? new trial aims to find out.
NCT ID NCT07282288
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new treatment for women whose ovaries don't respond well to fertility drugs, making it hard to get eggs for IVF. Doctors will take cells from the patient's own fat or blood and inject them into the ovaries. The goal is to see if this improves egg count and pregnancy rates. The trial involves 198 women and will check safety and effectiveness.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 198 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Dec 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Women who have fertility requirements and are seeking IVF treatment 2. Age ≤ 45 years old, infertility duration ≥ 1 year 3. Meeting the diagnostic criteria for POI or the Poseidon diagnostic criteria for POR 4. Previous controlled ovarian stimulation resulted in no more than 3 oocytes retrieved and/or no transplantable embryos and/or previous embryo implantation failure ≥ 2 times 5. Uterus and bilateral adnexa are intact 6. BMI 22 - 29 kg/m² 7. Participants must have given informed consent for this study and voluntarily signed a written informed consent form. Exclusion Criteria: 1. Congenital abnormalities of reproductive organs 2. Septicemia, platelet dysfunction syndrome and severe thrombocytopenia and other coagulation disorders or other hematological diseases 3. Suffering from autoimmune diseases or other endocrine disorders, with abnormal thyroid function and uncontrolled condition 4. Having a mass in the adnexal area with an unclear benign or malignant nature 5. Complicated with severe cardiovascular and cerebrovascular diseases, malignant tumors, hematological diseases and mental disorders, patients with impaired function of important organs 6. Those who have used systemic corticosteroids within the last 2 weeks, or used antiplatelet drugs such as aspirin within the last 48 hours 7. In the acute inflammatory stage 8. Those with a history of venous thrombosis or pulmonary embolism during the screening period
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Three ways to trigger ovulation: which yields more mature eggs in Low-Reserve IVF?
- Scientists hunt for hidden clues to help women with low egg reserve
- Could a blood treatment revive Low-Ovarian-Response? new study investigates
- Can a blood injection boost fertility? new trial tests PRP for poor ovarian response