Peking University First Hospital

This study looks at whether adding a precise type of radiation called SABR to standard targeted therapy and immunotherapy can help people with kidney cancer that has come back or spread. The goal is to improve how long the cancer stays under control and possibly extend survival. …

This study tests whether carefully managing body temperature during major cancer surgery can lower the risk of postoperative delirium (sudden confusion) and improve long-term survival in patients aged 65 and older. About 4,000 participants will be randomly assigned to either stan…

This study tests whether a special AI-enhanced ECG device can help people with moderate-to-advanced chronic kidney disease keep their potassium levels in check. Participants will use the device at home at least twice a week and get alerts if potassium is too high. The goal is to …

This study tests whether a new drug (rezvilutamide) plus hormone therapy can prevent high-risk salivary duct cancer from returning after surgery. About 37 adults with a specific type of this rare cancer will receive the treatment for up to 2 years. The goal is to see if the combi…

This study tests whether adding a special type of PET/CT scan (CAIX-targeted) to standard treatment can help doctors precisely target and radiate kidney cancer that has spread. About 70 adults with recurrent or metastatic clear cell renal cell carcinoma will receive standard ther…

This study tests whether a targeted drug (disitamab vedotin) plus radiation can prevent cancer from returning in people with HER2-positive upper urinary tract cancer who have high risk of recurrence after surgery. About 60 adults will either receive the 6-month combo therapy or s…

This study tests a simpler treatment for H. pylori infection, a stomach bug that can cause ulcers. Researchers use a stool test to check if the bacteria are resistant to the antibiotic clarithromycin. If not resistant, patients take a two-drug combination (vonoprazan and clarithr…

This study looks at whether a lower dose of aspirin (50 mg daily) works as well as the standard dose (100 mg) to prevent heart attacks and strokes in people aged 60 and older with heart disease. It involves over 5,400 Chinese participants who will be followed for about 6 years. T…

This study tests a new, minimally invasive brain stimulation technique for people with cerebellar cognitive affective syndrome (CCAS) caused by Cushing's syndrome. The treatment uses a device placed near the cerebellum to improve both thinking and movement. The trial will enroll …

This study looks at whether combining radiation and immunotherapy works better than standard chemotherapy for people with high-risk upper urinary tract cancer. The goal is to prevent the cancer from coming back after surgery. About 178 adults with certain high-risk features will …

This study tests a new type of PET/CT scan (68Ga-Pentixafor) to see if it can accurately identify which adrenal gland is making too much hormone in people with a specific adrenal condition (PA+MACS). About 130 adults will get the scan and have their results compared with standard…

This study compares two prostate biopsy techniques to find which better detects aggressive prostate cancers while avoiding overdiagnosis of harmless ones. About 592 men with a suspicious MRI finding will be randomly assigned to one of two biopsy methods. The goal is to improve ac…

This study tests a new imaging probe called 68Ga-PFA2 for PET scans to see if it can better detect cancer that has spread in people with lung cancer. The probe targets a protein called Annexin A2, which is often found in high levels on many cancer cells. Researchers will compare …

This early-phase study tests a new PET imaging probe called 68Ga-NB381 that targets a protein (CD38) found on multiple myeloma cancer cells. The goal is to see if this scan can detect the disease more accurately than current methods, potentially reducing the need for invasive bon…

This study aims to train a computer model to automatically tell the difference between early (T1-T2) and more advanced (T3) kidney cancer on CT scans. Researchers will use scans from 1,000 patients to develop and test the AI tool. If successful, this could help doctors make more …

This study is testing whether artificial intelligence can help doctors find adrenal nodules (small growths on the adrenal glands) in low-dose chest CT scans taken during routine checkups. Researchers will collect 600 chest CT images and train an AI algorithm to detect these nodul…

This study is testing a new type of PET/CT scan that uses a special tracer called 18F-T2 to find cancers that have high levels of a protein called CAIX. About 200 adults with cancers like kidney, bladder, lung, or breast cancer will get this scan to see if it works better than th…

This study tests a new radioactive probe called PFD3 that targets a protein (DLL3) found on small cell lung cancer cells. Using PET/CT scans, doctors hope to see tumors more clearly and assess the cancer's spread. About 30 adults with confirmed small cell lung cancer will receive…

This study looks at whether combining two sedatives—dexmedetomidine and esketamine—can reduce delirium (sudden confusion) in older patients recovering in the ICU after surgery. Delirium is common and can lead to worse outcomes. The trial will involve 100 adults aged 60 and older …

This study tests whether a nasal spray containing two medicines (dexmedetomidine and esketamine) can reduce pain in children after tonsil and adenoid surgery. About 160 children aged 3 to 7 will take part. The goal is to find a safe and effective way to manage pain without strong…

This study tests whether a new painkiller called anrikefon can better control internal pain after laparoscopic (keyhole) surgery. About 140 adults having colorectal surgery will receive either anrikefon or a standard painkiller through a pump they control. The goal is to see if a…

This study tests whether giving dexmedetomidine and esketamine during and after surgery helps patients feel better and recover faster. About 316 adults having surgery under general anesthesia will take part. The goal is to see if these drugs improve pain, comfort, and emotional w…

This study tests whether a personalized form of transcranial magnetic stimulation (rTMS) can improve movement and non-movement symptoms in people with Parkinson's disease, multiple system atrophy, or progressive supranuclear palsy. Fifty adults aged 30-80 will receive 10 daily se…

This study will enroll 150 adults with type 1 diabetes to see if a structured education program, combined with regular clinic visits, improves blood sugar control and self-management. Participants will attend classes covering diet, exercise, insulin use, and more, then be followe…

This study aims to discover new biological markers in blood, urine, and adrenal tissue that could help doctors diagnose primary aldosteronism earlier. Primary aldosteronism is a common but often missed cause of high blood pressure that can lead to heart and kidney problems. Resea…

This study aims to create an AI-powered early warning system to screen men aged 50 and older for prostate and bladder cancer. Researchers will test if this system can help find cancers sooner by coordinating care between community clinics, hospitals, and specialists. The goal is …

This study looks at whether new markers in blood and urine can better predict kidney injury after kidney removal surgery than current standard tests. About 60 adults scheduled for surgery will provide samples before and after the procedure. The goal is to find faster, more accura…

This study is observing people who have severe allergic reactions during surgery to better understand how to diagnose them and find out what caused the reaction. Researchers will use blood tests and skin tests to confirm the allergy. The goal is to improve safety for future surge…

This study aims to create a reliable way to predict whether a person with inflammatory bowel disease (IBD) will respond to expensive biologic drugs. Researchers will collect data from 200 patients, including symptoms and lab results, and use machine learning to build a prediction…

This study looks at whether taking out the breathing tube after robotic surgery in the recovery room instead of the operating room can save time. About 218 adults having robotic surgery will be randomly assigned to have their tube removed in the OR or the recovery room. The goal …

This study is testing a new, advanced ultrasound technique that can see tiny blood vessels in the legs. Researchers want to know if this imaging can help predict future problems in people with peripheral artery disease (PAD). About 300 adults with PAD will get this special ultras…

This study is creating a system to identify people at high risk for type 1 diabetes (T1D) before symptoms appear. Researchers will follow 340 participants—including T1D patients, their close relatives, and healthy volunteers—for up to 4 years. They will collect blood, urine, and …

This study aims to develop a computer model that uses MRI scans and patient information to predict whether a man has clinically significant prostate cancer (csPCa). Researchers will analyze data from 3,000 men who had an MRI and a prostate biopsy. The goal is to create a tool tha…