Ohio State University Comprehensive Cancer Center

This small, completed study tested whether a short, highly targeted course of radiation given before surgery was a practical option for older women with early-stage, hormone-sensitive breast cancer. The goal was to see if this approach could shrink the tumor and potentially allow…

This study tested whether combining two drugs could help people with certain blood cancers that had returned after previous treatment or were newly diagnosed. The trial included 41 adults with chronic lymphocytic leukemia or similar conditions. Researchers gave participants an an…

This study tested a combination of two drugs, ruxolitinib and CPX-351, for people with advanced forms of certain blood cancers. The main goals were to find the safest dose of the combination and to see how well it worked to control the disease. The treatment aimed to reduce cance…

This study tested whether adding the drug romidepsin to a stem cell transplant could better control several aggressive types of T-cell blood cancers. Researchers gave romidepsin before and after the transplant to 23 patients to find the safest dose and see if it helped. The main …

This study tested a two-drug combination (fulvestrant and palbociclib) to control breast cancer in patients aged 70 and older who could not undergo surgery due to frailty or who refused it. The goal was to see if this non-surgical approach could keep the cancer from growing for a…

This study tested whether a short video could help people who carry a BRCA gene mutation encourage their family members to get tested. 58 participants were randomly assigned to either receive a video via text message or a traditional letter in the mail. The goal was to see which …

This study tested if mailing HPV self-test kits to women could help more of them get screened for cervical cancer. Researchers compared two groups: one received the home test kit in the mail, and the other received a standard reminder letter to get screened at a clinic. The goal …

This study tested whether a 12-week online program of nutrition counseling and resistance training could help older adults who have completed cancer treatment. Researchers worked with 75 participants aged 65+ who had finished treatment for early-stage breast, colorectal, or prost…

This study tested whether a 12-week virtual support program could help older adults with advanced lung cancer feel better physically and emotionally during their cancer treatment. One hundred participants aged 60 and older were randomly assigned to either receive the support prog…

This study tested whether group Argentine Tango dance classes could help breast cancer survivors manage chemotherapy side effects better than standard home exercises. Fifty-two survivors with neuropathy symptoms were randomly assigned to either take 16 Tango classes or follow a h…

This study aimed to understand how people who use smokeless tobacco in rural Ohio and Appalachia respond to newer nicotine pouches. Researchers tested two popular brands (ZYN and Rogue) against participants' usual smokeless tobacco to measure appeal and nicotine delivery. The goa…

This study tested how synthetic cooling agents, which tobacco companies are adding to cigarettes, affect smoking behavior and appeal. Researchers had 34 young adult smokers try different cigarette types to see if these new additives make cigarettes more appealing or addictive. Th…

This study aimed to screen endometrial cancer patients for specific genetic changes in their tumors to better understand their disease. By testing over 1,000 patients, researchers looked for inherited cancer risks and genetic markers that could predict how well treatments might w…

This study aimed to understand how young adults perceive and use e-cigarettes containing a new chemical called 6-methyl nicotine compared to regular nicotine. Researchers enrolled 53 young adult e-cigarette users who tried different vaping products in lab sessions and answered qu…

This study aimed to understand how a person's genetic makeup affects how quickly their body processes a high-dose chemotherapy drug called methotrexate, which is used to treat certain lymphomas. Researchers studied 20 adult patients to see if specific gene variations were linked …

This study surveyed 109 breast and prostate cancer patients to understand how often they used vitamins, supplements, and other alternative therapies while undergoing radiation treatment. Researchers asked patients at three different times to see if their use of these therapies ch…

This study tested an online training program for community healthcare providers to improve their knowledge of cancer survivorship care. Twenty-eight nurses, doctors, and other providers from Ohio attended six virtual sessions over 12 weeks. The goal was to see if the training inc…