Ohio State University Comprehensive Cancer Center

This study tested a personalized geriatric optimization plan (GO!) in 30 patients over 60 receiving a stem cell transplant for blood cancers or bone marrow failure. The plan included tailored changes to diet, sleep, activity, and medications. The goal was to see if these changes …

This study tested a combination of two hormone-based drugs (fulvestrant and palbociclib) in 14 older patients with hormone-sensitive breast cancer who could not have surgery or chose not to. The goal was to control the cancer and avoid the need for surgery. The treatment aims to …

This early-phase study tested adding the drug romidepsin to standard chemotherapy before and after a stem cell transplant in 23 people with certain T-cell cancers. The goal was to find a safe dose and see if the combination could help control the cancer. Participants received the…

This study looked at whether switching from regular cigarettes to either low or high wattage e-cigarettes helps people smoke less or quit. 372 adult smokers who weren't planning to quit joined the study. Researchers measured how many people stopped smoking and checked their breat…

This study tested a combination of two drugs, MOR00208 and lenalidomide, in 41 people with chronic lymphocytic leukemia (CLL) or related blood cancers. The goal was to see if the combination could shrink or control the cancer in patients who had not responded to prior treatments …

This study tested new adhesive sensors that stick to the skin to detect early signs of lymphedema, a painful arm swelling that can happen after cancer treatment. Researchers compared 76 people with and without lymphedema to see if the sensors could tell the difference. The goal i…

This study tested whether offering a simple at-home HPV self-test kit could help more women in Appalachia get screened for cervical cancer. Over 800 women who were behind on screening took part. The goal was to see if this easy, private option would increase screening rates and c…

This study tested whether a special diet that keeps insulin levels low can reduce breast cancer risk in women already at high risk. The diet includes more fruits, vegetables, whole grains, and plant proteins, while limiting animal protein and unhealthy fats. Researchers worked wi…

This study tested whether an online program that teaches older adults (65+) who have had breast, colorectal, or prostate cancer how to eat more protein and do resistance exercises can improve their physical function. The program included counseling from dietitians and exercise ex…

This study tested an online Tai Chi program to help cancer survivors stop smoking. 68 cancer survivors who smoked took part in an 8-week program of slow movements and breathing exercises. The goal was to see if Tai Chi could help them quit and reduce their smoking.

This study looked at whether group dance classes can help breast cancer survivors who have nerve damage (neuropathy) from chemotherapy. 52 survivors took part to see if dancing improves balance and makes them feel better. The goal was to find a fun, social way to ease treatment s…

This study tested a program called ROAR-LCT for older adults (age 60+) with advanced lung cancer. The program combined physical therapy and relaxation exercises to improve physical and emotional wellbeing during cancer treatment. About 100 participants took part to see if the pro…

This study tested whether giving a high dose of focused radiation to the tumor before surgery is a safe and effective approach for older patients with early-stage, hormone-sensitive breast cancer. The goal was to shrink the tumor and reduce the amount of healthy tissue removed du…

This study tested whether a short video sent by text message could help people with BRCA gene mutations talk to their relatives about getting tested themselves. About 58 people who had a BRCA mutation took part. The goal was to see if the video made it easier to share important h…

This study surveyed 109 men with prostate cancer and women with breast cancer who were starting radiation therapy. Researchers asked about their use of nutritional supplements and complementary or alternative medicine (CAM) at three different times to see if their habits changed.…

This completed study looked at how 53 young adults (ages 21-34) who regularly vape perceive e-cigarettes containing 6-methyl nicotine (metatine) compared to regular nicotine. Researchers measured how the body processes these chemicals, puffing behavior, sensory experiences, appea…

This study examined lung cells from 66 smokers to see how switching to e-cigarettes or nicotine replacement therapy changes the lungs. Researchers used a camera down the airway to collect samples and look for early signs of cancer. The goal was to understand the health effects of…

This study analyzed blood, urine, and tissue samples from 273 adults with lung or brain cancer who were receiving radiation therapy. The goal was to find biomarkers that could predict which patients are more likely to develop serious side effects from radiation, such as lung infl…

This study measured heavy metal levels in the saliva of 58 young adults (ages 18-29) who use e-cigarettes regularly. Participants provided saliva samples and took a breathing test before and after a 30-minute vaping session. The goal was to see how vaping affects heavy metal expo…

This study tested a training program for community healthcare providers to improve their knowledge and skills in caring for cancer survivors. 28 providers from Ohio hospitals participated in virtual sessions. The goal was to see if the program increased their comfort and ability …

This study looked at whether specially designed text messages about the risks of using multiple tobacco products (like cigarettes and vapes) can help LGBTQ+ young adults quit or change their smoking habits. About 292 people took part. The messages were tailored to their community…

This study tested a new mobile 3D scanning app to measure swelling (lymphedema) in the head and neck area. Researchers wanted to see if the app could accurately track changes in swelling over time. Thirteen patients with head and neck lymphedema took part. The goal is to give doc…

This early-phase study enrolled 60 men with prostate cancer who were scheduled for surgery. They consumed black raspberry products so researchers could measure how the body absorbs and processes the fruit's natural compounds. The goal was to gather information for future studies …

This study looked at 182 older adults with blood cancer or lung cancer to see if a special calculator could predict who would have severe side effects from chemotherapy. Researchers measured patients' overall wellness before and after treatment. The goal is to help doctors choose…

This study looked at how genetic differences affect the body's ability to clear high-dose methotrexate in patients with diffuse large B-cell lymphoma. Researchers analyzed DNA from 20 participants to find specific gene variations linked to slower drug clearance. The goal was to b…

This study looked at how nicotine pouches, a new type of smokeless tobacco product, are used and perceived by adults in rural and Appalachian Ohio. Researchers wanted to understand how these products might affect public health. 71 daily smokeless tobacco users took part in the st…

This study looked at whether synthetic cooling agents, used as a replacement for menthol in cigarettes, change how appealing or addictive the cigarettes are. 34 young adult smokers tested three types of cigarettes: menthol, non-menthol, and those with synthetic coolants. Research…

This study screened over 1,000 women with endometrial cancer for DNA repair problems and Lynch syndrome, an inherited condition that raises cancer risk. By analyzing tumor DNA, researchers aimed to personalize treatment and identify at-risk relatives. The goal was to improve surv…