Ohio State University Comprehensive Cancer Center

This study tests a procedure that uses a thin, flexible tube with an ultrasound probe to guide a needle into pancreatic cysts. Chemotherapy drugs are then injected directly into the cyst to shrink or destroy abnormal cells. The goal is to prevent these precancerous cysts from dev…

This study tests whether some people with early-stage breast cancer can safely avoid surgery after chemotherapy and radiation. Participants will be monitored with MRIs, mammograms, and blood tests to check if the cancer stays away. The goal is to see if a non-surgical approach wo…

This study tests two programs that combine physical therapy and relaxation techniques, one in-person and one virtual, for adults about to have lung cancer surgery. The goal is to see if starting these programs before surgery helps people recover faster, feel better, and have a sh…

This study tests a new device called the Buckeye Quit Stick, designed to help smokers with lung cancer quit by replacing the hand-to-mouth habit of smoking. About 30 participants will use the stick for 6 months to see if it helps them stay smoke-free. The goal is to see if this a…

This study looks at whether a spinal tap (lumbar puncture) can find bits of tumor DNA in the fluid around the brain and spine. It includes 40 people with stage III or IV non-small cell lung cancer, who are at risk for the cancer spreading to the brain. The goal is to see if this …

This study looks at whether menthol cigarettes are more addictive than non-menthol ones. About 48 daily smokers who use menthol cigarettes will test different cigarette types in a lab and at home. Researchers will measure nicotine levels, smoking habits, and how appealing each ci…

This study looks at how adults use nicotine pouches to help create better public health rules. About 15 people who use nicotine pouches daily will take part. They will use study-provided pouches and attend three visits to measure nicotine levels and switching behavior.

This study looks at whether raising taxes on e-cigarettes with features that appeal to young people (like flavors) can discourage teens and young adults from using them, while also encouraging adult smokers to switch away from regular cigarettes. Researchers will survey about 3,4…

This study looks at how e-cigarette users respond to nicotine analogs—chemicals similar to nicotine—compared to regular nicotine. The goal is to learn whether these analogs are addictive. About 70 adult e-cigarette users will take part in lab visits to measure cravings, withdrawa…