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Gene study may predict chemo side effects in lymphoma

NCT ID NCT06031194

First seen Nov 01, 2025 · Last updated May 19, 2026 · Updated 30 times

Summary

This study looked at how genetic differences affect the body's ability to clear high-dose methotrexate in patients with diffuse large B-cell lymphoma. Researchers analyzed DNA from 20 participants to find specific gene variations linked to slower drug clearance. The goal was to better understand why some patients experience more side effects, which could help personalize treatment in the future.

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Contacts and locations

Locations

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

Conditions

Explore the condition pages connected to this study.