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Vaping study reveals hidden metals in young users' saliva

NCT ID NCT07215065

Knowledge-focused Sponsor: Ohio State University Comprehensive Cancer Center Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 58 young adults aged 18-29 who regularly use e-cigarettes. Researchers measured heavy metals in their saliva and tested their lung function before and after a 30-minute vaping session. The goal was to understand how vaping exposes the body to metals and affects breathing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

58 people

The number who actually took part.

Started

Oct 2025

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Young adults (aged 18 - 29 years) who are established and current EC users.

Ages

18 to 29 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 18-29 years * Established electronic cigarette (EC) user (participant uses ECs on a daily/weekly basis \[used on ≥ 5 days in past 30-days\] for the past 3 months) * Willing to abstain from nicotine for at least 12 hours before the laboratory visit * Willing to not eat food or drink water/beverages for at least 30 minutes before the laboratory visit \[required for salivary collection\] * Utilize 4th generation EC products (pod-mod or disposable EC products; e.g., JUUL, Hyde) * Must be able to read and write in English Exclusion Criteria: * Recently COVID-19+ (defined as a positive test in the past 30 days) or a recent COVID-19 hospitalization (within the past 6 months) * Attempting to quit the use of ECs * Is pregnant, planning on becoming pregnant and/or breastfeeding \[will be verified using a urine pregnancy test\] * Self-reported severe or significant psychological and/or psychiatric conditions \[e.g., not currently receiving treatment/medication; only past and/or stable conditions will be allowed\] * A history of cardiac events and/or distress within the past 3 months * Diagnosed with a chronic, serious lung disease or current infection (e.g., pneumonia, pulmonary edema) * Are deaf, hard of hearing, or have a severe motor disability

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Conditions

The condition(s) this trial relates to.

heavy metal poisoning

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Heavy metal exposure from vaping

Contacts and locations

Locations

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States