Nemours Children's Clinic

This study tests whether giving overweight teens free fruits and vegetables from a local farm, along with educational videos, can help them eat better and improve their blood pressure and weight. About 50 teens aged 12-17 will take part for 8 weeks. Researchers will track how man…

This study tests if laser hair removal can stop pilonidal disease from returning in people with darker skin (Fitzpatrick types IV-VI). About 36 participants aged 10-21 will be followed for one year to see if they develop new abscesses or infections. The goal is to find a simple w…

This study aims to improve ear reconstruction surgery for children and young adults with ear differences due to birth defects, injuries, or cancer. Researchers are testing a new medical device that helps shape cartilage into a more natural-looking ear framework, potentially reduc…

This study tests whether using a continuous glucose monitor (CGM) helps overweight teens with prediabetes follow lifestyle changes better. The goal is to improve insulin sensitivity and lower the risk of developing type 2 diabetes. About 15 teens aged 10 to 17 will use a CGM alon…

This study tests a new care approach for 80 young adults with type 1 diabetes who are moving from pediatric to adult healthcare. The program includes a nurse educator, psychologist, and transition navigator working together to provide support. The goal is to see if this team-base…

This study helps 50 children (ages 6 to 17) with type 1 diabetes who have high blood sugar levels and come from low-income families. Participants will receive advanced insulin pumps and continuous glucose monitors with help from an insurance navigator. The goal is to see if using…

This study tests whether using ultrasound instead of X-rays can diagnose elbow fractures in children more efficiently. About 225 kids with elbow pain will be randomly assigned to get an ultrasound or an X-ray. Researchers will compare costs, radiation exposure, time spent in the …

This study tests a smartphone chatbot called NUDGE that helps teens and young adults (ages 13-25) with cystic fibrosis set activity goals, track progress, and stay motivated. Researchers want to see if the app is easy to use and keeps people engaged. The goal is to help participa…

This study tests a program called R2D2 that helps families of children with type 1 diabetes cope with diabetes-related stress. The program screens for distress and offers treatment to improve blood sugar control and quality of life. About 180 children aged 8-12 and their parents …

This study looks at whether a GLP-1 agonist (a type of drug used for diabetes and weight loss) can help restore normal hormone rhythms in obese teenage girls with Polycystic Ovary Syndrome (PCOS). Twenty girls aged 12–18 will take the drug for 16 weeks along with diet and exercis…

This study tests a new, non-invasive sensor to detect lung problems in 250 children with severe cerebral palsy. The goal is to create a simple screening tool for respiratory distress and to see how lung function relates to scoliosis. Participants wear a sensor that measures breat…

This study tests a program that helps teens and young adults (ages 15-25) with sickle cell disease work with their doctors to choose the best treatment. About 68 patients, their families, and doctors will try a shared decision-making toolkit that includes virtual reality or stand…

This study is for people with Morquio A, a rare disease that affects bones and breathing. Researchers will use safe, non-invasive tests like X-rays, MRI, and breathing tests to track how the disease changes over time. The goal is to better understand the disease and find better w…

This study is testing whether a child's genes and physical exam can predict if they will respond to albuterol, a common breathing treatment, for bronchiolitis. Researchers will give 400 children aged 3 to 24 months either albuterol or a placebo and measure changes in breathing. T…

This study creates a registry for people with microcephalic primordial dwarfism and related conditions. Researchers will collect health information over time to understand how these rare diseases progress and affect people throughout their lives. The goal is to improve future car…

This study tests a new device called pneuRIP that measures breathing without needles or tubes. It will be used on 20 children—10 healthy and 10 with mild breathing problems from muscle diseases. The goal is to see if the new monitor works as well as an existing one.