Nemours Children's Clinic

This study tests if laser hair removal can stop pilonidal disease from coming back in people with darker skin (Fitzpatrick types IV-VI). About 36 people aged 10-21 will be in the trial. The main goal is to see if the laser treatment reduces the need for antibiotics or surgery for…

This study tests whether using a continuous glucose monitor (CGM) helps overweight teens with prediabetes follow lifestyle changes better than lifestyle changes alone. The goal is to improve insulin sensitivity and lower the risk of developing type 2 diabetes. About 15 teens aged…

This study tests a new medical device that helps surgeons shape cartilage into a more natural-looking ear for children and young adults with missing or deformed ears due to conditions like microtia, injuries, or cancer surgery. About 30 participants aged 5-20 will be enrolled. Th…

This study tests a new care model for 80 young adults with type 1 diabetes as they move from pediatric to adult healthcare. The model includes a nurse educator, psychologist, and transition navigator working together to address emotional and practical challenges. The goal is to i…

This study enrolls 50 children and teens (ages 6 to under 18) with type 1 diabetes who have high blood sugar levels and come from low-income families. Participants will receive help getting approved for advanced insulin pumps and continuous glucose monitors, with an insurance nav…

This study is testing whether using an ultrasound machine in the emergency room can be a good alternative to X-rays for diagnosing elbow fractures in children. Researchers will compare two groups of children with elbow pain: one group gets an ultrasound, and the other gets standa…

This study tests a smartphone chatbot called NUDGE that helps teens and young adults with cystic fibrosis (ages 13-25) set and track physical activity goals. The goal is to see if the app keeps them active or gently encourages more movement. The study will enroll 30 people and me…

This study looks at whether a GLP-1 medication (a type of drug used for weight loss and diabetes) can improve the brain's control of reproductive hormones in obese teenage girls with PCOS. About 20 girls aged 12–18 will take the drug for 16 weeks while also getting diet and exerc…

This study tests whether giving overweight teens free fruits and vegetables from a local farm for 8 weeks can help them eat more produce and improve their blood pressure and weight. About 50 teens aged 12-17 will get weekly produce and watch educational videos. Researchers will m…

This study tests a program called R2D2 that helps families of children with type 1 diabetes cope with the emotional stress of managing the condition. The program screens for diabetes distress and offers treatment to reduce that stress, with the goal of improving children's blood …

This study creates a registry for people with microcephalic primordial dwarfism and related conditions. Researchers will collect health information over time to understand how these rare diseases progress and affect people throughout their lives. The goal is to improve future car…

This study is for people with Morquio A, a rare disease that affects bones and breathing. Researchers want to learn more about how the disease progresses by using safe, non-invasive tests like X-rays, MRIs, and breathing tests. The goal is to find better ways to measure the disea…

This study looks at 400 children aged 3 to 24 months with bronchiolitis, a common lung infection in babies. Researchers want to see if certain genes and physical signs can predict who will improve with a bronchodilator like albuterol. Participants receive either albuterol or a pl…

This study tests a new device called pneuRIP that measures breathing without needles or tubes. It uses special bands placed around the chest and belly. The study will include 10 healthy children and 10 children with mild breathing problems from muscle diseases. Researchers will c…

This study is testing a new, non-invasive sensor to detect lung problems in 250 children with severe cerebral palsy. The goal is to create a simple screening tool that can spot breathing issues early and see how lung health relates to spine curvature. No treatment is given—the st…

This study tests a program that helps teens and young adults (ages 15-25) with sickle cell disease work with their doctors to choose the best treatment. About 68 patients, their families, and 8 doctors will take part. The program includes virtual reality or standard education mat…