Nemours Children's Clinic

This study tests a new care model for 80 young adults with type 1 diabetes who are moving from pediatric to adult healthcare. The program includes a nurse educator, psychologist, and transition navigator working together to provide support over six months. The goal is to see if t…

This pilot study tests whether a special diet based on a baby's lean body mass can help large newborns (born with excess body fat) who struggle with oral feeding. Researchers will compare this tailored feeding approach to standard care in 40 infants. The goal is to see if the die…

This study gives overweight teens ages 12-17 free weekly produce from a local farm for 8 weeks, along with educational videos. Researchers want to see if this program is practical and if it increases fruit and vegetable intake, improves blood pressure, and helps with weight. Fift…

This study enrolls 50 children and teens (ages 6 to under 18) with type 1 diabetes who have high blood sugar levels and come from low-income families. Participants will receive help from an insurance navigator to get a closed-loop insulin pump and continuous glucose monitor. The …

This study tests a new medical device that helps surgeons shape cartilage into a more natural-looking ear for children and young adults with missing or deformed ears due to birth defects, injuries, or cancer surgery. About 30 participants aged 5-20 will be enrolled. The goal is t…

This study tests whether wearing a continuous glucose monitor (CGM) alongside lifestyle changes can improve insulin sensitivity in teens aged 10-17 with prediabetes. Fifteen overweight or obese participants will use the Dexcom G7 device to see real-time glucose data, aiming to bo…

This pilot study is testing whether laser hair removal can reduce the chance of pilonidal disease coming back in people with darker skin (Fitzpatrick types IV-VI). The study will enroll 36 people aged 10-21 who have had pilonidal disease. Participants will receive either standard…

This study tests whether a weekly injection of semaglutide (a GLP-1 drug used for obesity) can improve the brain's reproductive hormone signals in obese adolescent girls with polycystic ovary syndrome (PCOS). Twenty girls aged 12–18 will receive the drug plus lifestyle advice for…

This study looks at whether a simple ultrasound at the bedside can reliably detect vocal fold motion impairment in children who are on noninvasive breathing support in the ICU. About 50 children will get two ultrasounds of their vocal folds—one while on the breathing machine and …

This study tests whether using ultrasound instead of X-rays can diagnose elbow fractures in children more efficiently. About 225 kids with elbow pain will be randomly assigned to get either an ultrasound or an X-ray. Researchers will compare costs, radiation exposure, time spent …

This study is testing a new, non-invasive respiratory sensor (pneuRIP) to detect lung problems in 250 children with severe cerebral palsy. The goal is to see if the sensor can screen for issues like pneumonia or airway blockage, and to understand how lung function relates to spin…

This study tests a smartphone program called NUDGE that acts like a health coach for teens and young adults (ages 13-25) with cystic fibrosis. Participants set activity goals, track progress, and get feedback through the app. The goal is to see if the app helps them stay active a…

This study tests an online program called eSCCIP designed to help parents and caregivers of children with cancer feel less distressed and more able to cope. The program includes web-based modules and video sessions with a coach. Researchers will compare it to a basic informationa…

This study tests a program that helps teens and young adults (ages 15-25) with sickle cell disease work with their doctors to choose the best treatments. About 68 patients, their caregivers, and 8 doctors will take part. The program includes virtual reality or standard education …

This study is for children with Morquio A, a rare genetic disease that affects bones and breathing. Researchers will use safe, non-invasive tests like MRI, X-rays, hearing tests, and walking analysis to track how the disease changes over time. The goal is to better understand the…

This study looks at whether a common asthma drug, albuterol, helps babies with bronchiolitis (a lung infection). Researchers will give 400 children either albuterol or a placebo and check their breathing. They will also collect DNA samples to see if certain genes predict who gets…

This study tests a new device called pneuRIP that measures breathing without needles or tubes. It uses special bands placed around the chest and belly. Researchers will compare it to an existing monitor in 20 children—10 healthy and 10 with mild breathing problems from muscle or …

This study creates a registry to collect health information from 200 people with rare forms of primordial dwarfism, such as MOPDII and Meier-Gorlin syndrome. Researchers hope to learn how these conditions change over a person's lifetime and improve future care. Participants provi…