Medical University Of Graz

This study tests whether transplanting healthy donor stool into the gut can help people with severe gut inflammation after a stem cell transplant. About 15 participants with steroid-resistant graft-versus-host disease will receive the treatment via colonoscopy. The goal is to see…

This study tests whether a large dose of vitamin D3 can lower the risk of death within 28 days for critically ill adults with very low vitamin D levels. About 2,400 ICU patients will receive either vitamin D or a placebo. Earlier research suggested vitamin D might reduce deaths i…

This study tests whether bone from a donor (allogeneic) works as well as bone taken from the patient's own body (autogenous) for rebuilding the jawbone. About 26 people with missing teeth and thin jawbone will receive one of the two graft types. The goal is to see if both methods…

This study tests whether giving a combination of blood products (fibrinogen, plasma, and tranexamic acid) to trauma patients with life-threatening bleeding before they arrive at the hospital is feasible. Ten adults with signs of hemorrhagic shock will be included. The goal is to …

This study tests a new tool called the POPScore that uses light and vital signs to predict infection in newborns with breathing problems. The goal is to see if it can detect inflammation early, within the first 6 hours after birth. About 93 newborns will take part in this observa…

This study tests a portable DNA analyzer (Nanopore MinION) to quickly identify bacteria or fungi causing endophthalmitis, a severe eye infection. Researchers will compare the new method with standard lab cultures using samples from 20 patients. If successful, this approach could …

This study looks at whether giving surfactant over 1 minute or 5 minutes helps very premature babies (under 28 weeks) stay more stable. Surfactant is a lifesaving treatment for breathing problems. The researchers will measure oxygen levels in the blood and brain to see which spee…

This study follows 800 pregnant women to understand how conditions like obesity or diabetes during pregnancy impact the health of both mother and child over time. Researchers will track body composition, blood sugar, blood pressure, and other health markers through pregnancy and …

This study follows 400 pregnant women diagnosed with gestational diabetes to learn how the condition affects both mother and baby. Researchers will collect health data and samples during pregnancy, at birth, and a few months after delivery. The goal is to better understand the ri…

This study aims to find out how common functional neurological disorders are in people who already have a movement disorder like Parkinson's disease, tremor, or dystonia. Researchers will examine 216 participants with neurological exams, thinking tests, and questionnaires. The go…

This study is following 250 pregnant women diagnosed with preeclampsia, a serious condition involving high blood pressure and organ stress. Researchers will collect health data and samples from mothers and babies during pregnancy, at birth, and a few months after delivery. The go…

This study is creating a large database of information from 900 people who have pulmonary hypertension (high blood pressure in the lungs) or are at risk for it. Researchers will collect medical history, test results, and follow-up data over time. The goal is to improve understand…

This study watches how deeply heart surgery patients are sedated in the ICU using a brain activity monitor. It does not change their care, just observes. The goal is to learn how often patients are too deeply sedated and if that affects recovery, like how long they need a breathi…

This study looks at how Boswellia serrata, a herbal supplement used in Ayurvedic medicine, affects the way healthy people process pain. Researchers will use a capsaicin (chili pepper) cream to create temporary skin sensitivity and then measure pain responses. The goal is to under…

This study follows 100 people who had a heart attack to see how many develop anxiety or posttraumatic stress disorder (PTSD) later. Researchers want to understand if the fear, stress, and pain experienced during the heart attack play a role. Participants are adults aged 19–90 wit…

This study tests whether doing hand movements in virtual reality can reduce shaking in people with functional tremor. About 48 people with tremor or healthy volunteers will try VR tasks while researchers measure reaction time and brain activity. The goal is to learn how the brain…

This study looks back at medical records of 1000 people with COPD who had a special heart test. The goal is to learn more about a condition called pulmonary hypertension, where blood vessels in the lungs are under high pressure. By studying these records, researchers hope to bett…

This study looks at why bee venom allergy treatment (immunotherapy) fails in some people. Researchers will test 266 adults with bee sting allergies to see if having a strong allergy to a specific bee venom protein (Api m 10) makes treatment less effective. The goal is to improve …

This study is testing whether a blood test called BAT inhibition can reliably tell if venom immunotherapy has protected a person from allergic reactions to insect stings. Currently, the only way to be sure is to sting patients with live insects, which is not widely available. The…

This study creates a database to help doctors recognize early signs of interstitial lung disease (ILD) in patients who have other systemic diseases that put them at risk. About 412 adults will be screened using lung function tests. The goal is to improve early detection, not to t…

This study looks at how the bacteria in your gut might cause diarrhea during cancer treatment. Researchers will follow 150 adults starting cancer therapy, collecting stool and blood samples to see which bacteria are linked to diarrhea. The goal is to understand the connection so …

This study is a registry that collects information from 1,500 people with advanced pancreatic cancer in Austria. Researchers want to see which treatments are used and how well they work in real life. The goal is to find patterns that could help improve care for future patients.

This study is testing a new, non-invasive device that uses light to measure oxygen levels in the brains of newborn babies immediately after birth. The goal is to see if this method can provide more detailed information than current standard monitoring, especially for premature ba…

This study looks at how alcohol affects tremors in people with essential tremor, dystonia, and Parkinson's disease. 45 participants will receive either an alcoholic drink or a non-alcoholic placebo on two separate days. Researchers will measure tremor changes using a device and c…

This study looks at whether using a special blood test (thrombelastography) before a TIPS procedure can help doctors decide if patients with liver cirrhosis really need blood products or transfusions. The goal is to see if this approach is safe and reduces the amount of blood pro…

This study looks at whether a detailed, easy-to-understand explanation of a functional neurological movement disorder helps patients better grasp their condition and feel more satisfied with their care. About 35 adults with conditions like functional paralysis or tremors will rec…

This study is a registry that will collect information from about 1000 people with hypertrophic cardiomyopathy (a condition where the heart muscle is thickened) across multiple clinics in Austria. Researchers will gather data from medical records, tests, and genetic testing to be…

This study aims to find a simple blood test to detect pulmonary hypertension early in people with chronic lung diseases like COPD or pulmonary fibrosis. Researchers will analyze collagen fragments in blood and lung tissue from 80 participants to create a molecular fingerprint of …