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Ancient herb boswellia put to the test: can it soothe pain?

NCT ID NCT07109843

Knowledge-focused Sponsor: Medical University of Graz Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study is testing whether a supplement called Boswellia serrata (also known as frankincense) can change how healthy people feel pain. Twelve volunteers will take either the supplement or a placebo for a short time, then have a small amount of capsaicin (the stuff that makes chili peppers hot) put on their skin to cause temporary pain. Researchers will measure pain intensity and sensitivity to understand how Boswellia might work. This is a pilot study, meaning it is small and focused on learning, not on proving a treatment works.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Boswellia serrata extract (600 mg daily)
What this could lead to
If successful, this study could explain how Boswellia serrata reduces pain, pointing toward better use for chronic pain conditions.
What could go wrong
This is a very small pilot study in healthy people, not patients. It uses a temporary pain model, so results may not apply to real chronic pain. The supplement may also have no effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 12 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Dec 2025

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age: ≥18 years Exclusion Criteria: * Not pregnant or breastfeeding * No renal or liver insufficiency * No neurological/dermatological/cardiovascular diseases * No chronic pain and/or use of analgesics * No use of anticoagulants * No use of antidepressants * No use of MAO inhibitors * No use of St. John's Wort * No use of medications affecting the CYP mechanism * No allergies to Boswellia serrata or capsaicin"

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome neuronitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Central sensitisation Chronic pain Neuroinflammatory response Peripheral sensitization

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Medical University of Graz

    RECRUITING

    Graz, Styria, 8010, Austria

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