Loma Linda University

This study tests whether a team-based program called ARTAS can help people with HIV stay connected to care after they leave the hospital. Researchers will enroll 250 adults who are newly diagnosed or not currently in HIV care. The goal is to see if this approach improves follow-u…

This study compares two common blood pressure medicines, Nifedipine and Labetalol, to see which one works better and is safer for women who develop high blood pressure after giving birth. About 500 new mothers will take one of the two drugs, and researchers will track how well th…

This study tests whether giving chemotherapy and radiation before surgery can help surgeons remove all of the pancreatic cancer. About 30 adults with early-stage, removable pancreatic cancer will receive the drugs gemcitabine and nab-paclitaxel plus targeted radiation, then surge…

This study tests whether washing the wound and abdominal cavity with a diluted iodine solution during emergency abdominal surgery reduces the risk of surgical site infections compared to using saline. About 1,100 adults aged 18 to 80 with certain types of wounds will take part. T…

This study looks at whether a low dose (81 mg) of aspirin works as well as a higher dose (325 mg) to prevent strokes in people who have injured blood vessels in their neck or head from a blunt trauma, like a car accident. About 98 adults will be randomly assigned to one of the tw…

This study looks at two standard surgical techniques for removing a testicle due to suspected cancer. The goal is to see if one method causes less pain, less need for painkillers, and fewer complications after surgery. About 80 adults with testicular cancer will take part, and th…

This study looks at whether melatonin supplements can improve sleep and daytime functioning in teenagers aged 13-17 who have trouble sleeping. Each teen will try both melatonin and a placebo for two weeks each, while wearing a wrist monitor to track sleep. The goal is to see if m…

This study looks at whether adding a procedure called lateral pharyngoplasty to standard tonsillectomy helps children ages 3-17 recover better. Researchers want to see if it reduces pain, helps kids eat and drink sooner, and lowers the risk of bleeding after surgery. About 160 ch…

This study looks at whether short-term circuit strength training can help sedentary postmenopausal women improve muscle mass, sleep quality, balance, and overall well-being. Researchers will also measure inflammation levels. The goal is to give healthcare providers evidence that …

This study compares two non-invasive treatments for nerve pain caused by type 2 diabetes: Intraneural Facilitation Therapy (INF) and standard physical therapy. Forty adults aged 45-85 with moderate to severe diabetic neuropathy will be randomly assigned to one of the two groups. …

This study tests a gentle, hands-on treatment called strain-counterstrain for pain caused by the piriformis muscle, a small muscle deep in the buttock. Researchers want to see if this non-invasive method can reduce pain and improve daily activities like walking and sitting. The s…

This study tests whether a specially trained community health worker can improve symptoms and quality of life for people newly diagnosed with pancreatic cancer, and also help their caregivers. About 60 patients and their caregivers will be randomly assigned to either work with a …

This study tests whether a powered, computer-controlled prosthetic knee helps people with above-knee amputations use less energy while walking on flat and sloped surfaces compared to their usual prosthesis. Researchers will measure oxygen use, balance confidence, and perceived ef…

This study tests whether taking 600 mg of gabapentin two hours before wisdom tooth extraction can lower pain and reduce the need for opioid painkillers afterward. About 98 adults will be randomly assigned to receive either gabapentin or a placebo. Researchers will track opioid us…

This study looks at whether a special low-weight workout using blood flow restriction cuffs can help teenage rowers with mild or recurring low back pain. Researchers want to see if this method is as effective as heavy lifting for improving performance and preventing re-injury, bu…

This study looks at whether trouble sleeping contributes to central auditory processing disorder (CAPD) in children and teens with autism. Researchers will compare kids with autism who have CAPD to those who don't, using parent reports and clinical tests. The goal is to better un…

This study looks at whether magnesium sulfate, a common pain medicine given during surgery, changes the results of nerve monitoring tests used to protect the spinal cord and brain. About 50 adults having spine or brain surgery will be randomly assigned to receive either magnesium…

This study looks at how limited ankle movement affects the way people with knee pain perform single-leg squats. Researchers will measure ankle flexibility and knee pain in 60 women aged 18-59 who have had knee pain for at least 6 months. The goal is to better understand the conne…

This study looks at why teens with autism or schizophrenia struggle with social interactions. Researchers will use brain scans to see how a 16-week social skills program changes brain activity and connections. The goal is to find out what brain differences are shared or unique be…

This study looks at how the gums around a dental implant crown change shape when the crown is temporarily removed. Researchers want to know how long it takes for the gum to change enough to affect making a new crown. About 34 adults with a front tooth implant will have their gums…

This study looks at how a doctor's clothing affects patient trust. About 200 adults admitted to a hospital medical-surgical unit will fill out a survey about their preferences for traditional attire (street clothes and white coat) versus casual attire (surgical scrubs). The goal …

This study looks at whether adding health and resilience lessons to the regular coursework of occupational therapy students helps them live healthier, feel better about themselves, and reduce symptoms of depression and anxiety. About 130 students will take part over several years…

This study looks at whether intermittent fasting helps healthy adults lose body fat and improve their quality of life. Researchers will measure body fat percentage and visceral fat in 70 participants. The goal is to see if this eating pattern is a practical way to manage weight.

This study looks at whether the median nerve in the arm can be used to monitor muscle relaxation during surgery, instead of the usual ulnar nerve. About 32 adults having planned surgery will have both nerves tested. The goal is to see if the median nerve gives equally reliable re…

This study looks at whether using different X-ray settings can lower radiation exposure when placing a device to treat overactive bladder. About 44 adults will be randomly assigned to standard or experimental settings. The goal is to see if the new approach reduces radiation whil…

This study tests a program that brings together pediatricians, community health workers, and parenting educators to support families with adverse childhood experiences (ACEs). The goal is to lower stress and improve health in children ages 3 to 11. Researchers will compare famili…