Loma Linda University

This study compares toothpaste tablets to a standard toothpaste to see if they are equally good at removing plaque and keeping gums healthy. Fifty adults will use one of the two products for six weeks. Researchers will measure plaque, gum inflammation, and cavities before and aft…

This study tests if a special membrane made from donated placental tissue (amnion-chorion) can help repair bone loss around dental implants better than the standard collagen membrane. About 56 adults with peri-implantitis will receive one of the two membranes during surgery. Rese…

This pilot study tests whether a carefully designed diet (low salt, limited caffeine, high potassium, low phosphate, limited protein and carbs, with adequate water) can slow the growth of kidney cysts in people with autosomal dominant polycystic kidney disease (ADPKD). Researcher…

This study compares two pain relievers—lidocaine (a numbing medicine) and morphine (an opioid)—for people with severe kidney stone pain in the emergency department. Researchers want to see if lidocaine can provide similar pain relief without the risks of opioids. About 250 adults…

This study looks at whether a special therapy called Intraneural Facilitation (INF) and a diet plan can help people with type 2 diabetes who have nerve pain in their feet and legs. About 60 adults aged 35 to 85 will be split into three groups: one gets the therapy alone, one gets…

This pilot study tests whether Emotional Brain Training (EBT), a method that teaches skills to shift mood from negative to positive, can help manage stress, anxiety, and cravings in adults being treated for substance use disorders. About 54 participants will either receive standa…

This study compares a new pressure-limited nasal cannula (ADINA) to standard high-flow nasal cannula in premature babies with respiratory distress. About 40 newborns weighing 400-500 grams will take part. The goal is to see if ADINA reduces the time they need oxygen and works as …

This study looks at whether giving iron every day or every other day works better for children with iron deficiency anemia. About 100 kids aged 1 to 18 will take iron for 3 months, and doctors will check their blood to see which group improves more. The goal is to find a dosing s…

This study looks at whether eating certain seeds during different parts of the menstrual cycle can help make periods more regular, reduce cramps, and ease PMS symptoms. About 50 women with irregular cycles or painful periods will eat flax and pumpkin seeds early in their cycle, t…

This study tests a procedure called cryoablation, which uses cold to temporarily freeze nerves around broken ribs. The goal is to reduce severe pain, improve breathing, and prevent complications like pneumonia. About 30 adults with multiple rib fractures will be randomly assigned…

This study looks at whether eating mango can improve immune function and thinking skills in healthy college students aged 18 to 30. Researchers will measure changes in immune cells and cognitive test scores after mango consumption. The goal is to learn more about the potential be…

This study looks at whether giving extra breastfeeding education before birth helps more mothers exclusively breastfeed their babies for the first 6 weeks. About 196 first-time or short-term breastfeeding moms will be involved. The goal is to improve breastfeeding rates by teachi…

This study looks at whether eating 1.5 cups of fresh mango daily for 12 weeks can improve gut health in people with prediabetes. Researchers will measure markers of gut leakage and beneficial gut bacteria byproducts using stored blood samples from a previous trial. The study invo…

This study looks at how the natural twist of the shoulder bone (retroversion) and a player's biological age affect shoulder strength in baseball players. Researchers will measure rotation and grip strength in 120 healthy players. The goal is to better understand these factors, no…