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Nerve-Freezing technique could revolutionize rib fracture recovery

NCT ID NCT06533904

Symptom relief Sponsor: Loma Linda University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a procedure that freezes the nerves around broken ribs to see if it reduces pain and helps people breathe better. About 30 adults with at least two broken ribs and severe pain will either get the freezing treatment or standard pain medicine. Researchers will track pain scores, breathing tests, and recovery over time.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Jul 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * \> 18 years old * \> 2 rib fractures * Verbal Pain score \> 5 * Incentive Spirometry \< 60% of predicted Exclusion Criteria: * Isolated Fractures of Ribs 1-3 and/or 10-12 * Posterior Rib Fracture \< 4 cm from costovertebral joint * Sternal, Clavicle, Scapula Fracture * Thoracic Spinal Fracture of any type * Open Abdominothoracic Surgery * Unstable Spine * Extensive Subcutaneous Emphysema * BMI \> 35 * Plan for Rib Plating * Chronic Opioid Use * Prior to study enrollment: Intubated, Traumatic Brain Injury, Dementia, Cognitive Impairment, Encephalopathy * Coagulopathy, Shock at time of ablation * Inability to participate in activities of daily living prior to injury * Home O2 use prior to trauma * Inhalation Injury * Rib Fractures due to cardiopulmonary resuscitation * Life Expectancy \< 6 months * \> 48 hours from injury * Pregnant, Incarcerated

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Conditions

The condition(s) this trial relates to.

adult acute respiratory distress syndrome bone fracture Chest Pain Dyspnea injury respiratory distress syndrome in premature infants respiratory failure Rib Fractures

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chest wall disorder Pain, chest Respiratory distress syndrome Respiratory failure Respiratory insufficiency Rib fracture multiple Rib fractures Rib trauma Trauma

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Loma Linda University Health

    Loma Linda, California, 92354, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.