Istanbul University
Clinical trials sponsored by Istanbul University, explained in plain language.
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Knee repair combo shows promise for arthritis sufferers
Disease control CompletedThis study tested whether adding a special cell therapy (stromal vascular fraction) to a standard knee repair procedure (microfracture) helps people with knee osteoarthritis. 50 adults with moderate knee arthritis were split into two groups: one got the cell therapy alone, the ot…
Phase: NA • Sponsor: Istanbul University • Aim: Disease control
Last updated May 26, 2026 08:56 UTC
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Gum treatment may lower body inflammation and improve cholesterol
Disease control CompletedThis study looked at whether non-surgical gum treatment (deep cleaning) could reduce inflammation and improve blood fat levels in young adults with severe gum disease. Fifty participants, including a healthy comparison group, were followed for 6 months. Researchers measured marke…
Phase: NA • Sponsor: Istanbul University • Aim: Disease control
Last updated May 26, 2026 08:55 UTC
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Tooth nerve tests put to the test: which one tells the truth?
Diagnosis CompletedThis study looked at how well cold, heat, and electric tests can tell if a tooth's nerve is healthy or damaged. Researchers tested 175 adults who needed root canal treatment and compared the test results with directly looking at the nerve during the procedure. The goal was to fin…
Sponsor: Istanbul University • Aim: Diagnosis
Last updated May 26, 2026 08:58 UTC
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Ultrasound may spot carpal tunnel syndrome early
Diagnosis CompletedThis completed study looked at whether ultrasound measurements of the median nerve can help diagnose mild to moderate carpal tunnel syndrome (CTS). Researchers compared 75 healthy people and CTS patients, measuring nerve size and shape. They also checked how these ultrasound find…
Sponsor: Istanbul University • Aim: Diagnosis
Last updated May 26, 2026 08:56 UTC
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Home program cuts fall risk for seniors
Prevention CompletedThis study tested a nurse-led home fall prevention program for older adults (65+) at high risk of falling. 82 participants received exercises, safety checks, and education to reduce falls and improve balance. The goal was to see if this approach lowers fall rates, fear of falling…
Phase: NA • Sponsor: Istanbul University • Aim: Prevention
Last updated May 26, 2026 09:05 UTC
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Dancing away the pain: aerobic exercise shows promise for fibromyalgia
Symptom relief CompletedThis study tested whether aerobic dance exercises can help women with fibromyalgia feel better and function better in daily life. 44 women with fibromyalgia took part, comparing dance exercises to standard postural exercises. The goal was to see if dancing could reduce pain, impr…
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated May 26, 2026 09:04 UTC
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Jaw-Tracking tech could make mouthguards smarter and more comfortable
Symptom relief CompletedThis study tested whether custom mouthguards (splints) designed using a 3D jaw-tracking device called MODJAW work better than standard ones for people with teeth grinding or jaw pain. Forty adults with mild-to-moderate bruxism used either a personalized or standard splint for 8 w…
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated May 26, 2026 08:56 UTC
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Could a simple anesthesia change prevent lung collapse after surgery?
Symptom relief CompletedThis study looked at whether using a lower amount of fresh gas during anesthesia (low-flow) can reduce lung collapse (atelectasis) in adults having laparoscopic weight-loss surgery. Sixty patients were randomly assigned to receive either low-flow or normal-flow anesthesia. The re…
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated May 26, 2026 08:54 UTC
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Knee pain relief: which PRP works best?
Symptom relief CompletedThis study tested two different ways of preparing platelet-rich plasma (PRP) injections for people with knee osteoarthritis. The goal was to see which method better reduces pain, improves daily function, and enhances quality of life. 96 adults with mild-to-moderate knee arthritis…
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated May 26, 2026 08:53 UTC
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Can remote therapy boost hand function in kids with cerebral palsy?
Symptom relief CompletedThis study tested whether a special hand therapy (mCIMT) delivered via video calls helps children with unilateral cerebral palsy improve arm and hand function more than a standard home program. Forty-two children aged 4-12 took part. The therapy group did one-hour sessions three …
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated May 26, 2026 08:53 UTC
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Picture this: no more fear of the dentist!
Symptom relief CompletedThis study tested whether showing children pictures and explaining the dental environment before treatment could lower their anxiety. 70 children aged 5 to 14 took part, with half receiving the visual lesson and half getting standard care. Results showed that the visual group fel…
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated May 26, 2026 08:33 UTC
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Simple exercises may boost mouthguard therapy for jaw pain
Symptom relief CompletedThis study looked at whether adding postural or Rocabado exercises to a standard mouthguard (occlusal splint) can better reduce pain and improve jaw movement in people with internal temporomandibular joint (TMJ) disorders. Fifty-seven adults were split into three groups: mouthgua…
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated May 22, 2026 14:03 UTC
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New study compares two nerve blocks to reduce opioid use after gallbladder surgery
Symptom relief CompletedThis study looked at 120 adults having gallbladder removal surgery. Doctors compared two types of nerve blocks (erector spinae plane block and thoracic paravertebral block) to see which one better controlled pain after surgery. The main goal was to measure how much opioid pain me…
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated May 20, 2026 11:54 UTC
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New nerve block eases stubborn back pain in small study
Symptom relief CompletedThis study tested a new nerve block for people with myofascial pain syndrome, a condition causing deep muscle pain in the back. Sixty adults received either a standard trigger point injection or a newer erector spinae plane block. Researchers measured pain levels to see which met…
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated May 19, 2026 12:00 UTC
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Sugar water shots ease shoulder pain in new study
Symptom relief CompletedThis study tested whether injecting a sugar solution (dextrose prolotherapy) into the shoulder could reduce pain and improve function in people with chronic rotator cuff disease. Sixty adults aged 30 to 65 with shoulder pain lasting more than 3 months took part. The treatment aim…
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated May 14, 2026 12:06 UTC
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More wires, more infection risk in thigh bone surgery, study finds
Knowledge-focused CompletedThis study reviewed 148 patients who had thigh bone or hip replacement-related fracture surgery using metal wires (cerclage) to hold bone pieces together. Researchers found that the more wires used, the higher the chance of deep infection or persistent wound drainage. The key tak…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 26, 2026 09:00 UTC
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PCOS hormone secrets revealed: birth control pill effects measured
Knowledge-focused CompletedThis study looked at how birth control pills change hormone levels in 56 teens and young women (ages 13-21) with PCOS. Researchers measured specific hormones before and after 6 months of treatment. The goal was to understand the effects, not to test a new treatment.
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 26, 2026 08:59 UTC
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Study reveals hidden impact of breathing disorder in obesity
Knowledge-focused CompletedThis study looked at 64 obese adults to see if having obesity hypoventilation syndrome (OHS) adds extra problems beyond obesity alone. Researchers measured how far people could walk in 6 minutes, their muscle strength, and their quality of life. The goal was to understand if OHS …
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 26, 2026 08:59 UTC
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New scale validated to predict bedsores in turkish ICUs
Knowledge-focused CompletedThis study checked if a Spanish pressure injury risk scale, EVARUCI, works well in Turkish intensive care units. Researchers translated it and tested it on 100 adult patients without existing pressure injuries. The goal was to see if the scale reliably predicts risk in this new s…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 26, 2026 08:57 UTC
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ICU Nurses' eye care Know-How under the microscope
Knowledge-focused CompletedThis study surveyed 190 intensive care unit nurses from around the world to find out what they know and think about eye care for their patients. The goal was to see how well nurses follow expert guidelines for preventing eye problems in critically ill people. No treatments or cha…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 26, 2026 08:56 UTC
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Immune cell clues in kidney disease: no treatment, just observation
Knowledge-focused CompletedThis completed study looked at immune cells (T and B cells) in blood samples from 44 people with primary membranous nephropathy, a kidney disease. Researchers compared these cells to those from people with another kidney disease (IgA nephropathy) and healthy volunteers. The goal …
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 26, 2026 08:34 UTC
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Dental scan study seeks best retraction method for clearer images and patient comfort
Knowledge-focused CompletedThis study looked at 50 healthy adults aged 25-40 to find which retraction technique gives the best balance of clear scans, minimal tissue movement, and patient comfort during digital dental impressions. Participants had healthy gums and specific tooth types. The goal is to help …
Phase: NA • Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 22, 2026 14:04 UTC
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Push-Ups with a twist: can blood flow restriction boost explosive power?
Knowledge-focused CompletedThis study looked at how doing push-ups with different levels of blood flow restriction (using bands to partially limit arm circulation) affects upper body explosive power in 30 young volleyball players. Participants performed push-ups under various conditions, and their throwing…
Phase: NA • Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC
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Gum disease leaves telltale signs on jawbone x-rays, study finds
Knowledge-focused CompletedThis study looked at dental X-rays from 120 people—half with gum disease (periodontitis) and half healthy—to see if computer analysis could spot differences in jawbone structure. Researchers used special software to measure bone patterns and thickness. The goal was to find out if…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC
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Blood protein may forecast success of gastric bypass
Knowledge-focused CompletedThis study tested whether a blood marker called PTX3 can predict how well people with obesity respond to gastric bypass surgery. Researchers followed 23 adults for 6 months after surgery, measuring weight loss, inflammation, and insulin resistance. The goal was to see if PTX3 lev…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 22, 2026 13:50 UTC
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Oxygen study reveals Body's hidden stress during surgery
Knowledge-focused CompletedThis study looked at how giving more or less oxygen during laparoscopic lower abdominal surgery affects stress and inflammation in the body. 76 adults having planned surgery were randomly assigned to receive either normal oxygen or extra oxygen during the procedure. Researchers m…
Phase: NA • Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 22, 2026 13:50 UTC
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Rare disease hormone puzzle: new study looks for answers
Knowledge-focused CompletedThis study looked at whether people with Friedreich's ataxia have trouble making certain hormones. Researchers measured hormone levels in 11 patients and compared them to 15 healthy volunteers. The goal was to learn more about how the disease affects the body's hormone system, no…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 14, 2026 12:06 UTC
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Emergency disconnect: do dialysis patients know how?
Knowledge-focused CompletedThis study looked at whether people on hemodialysis know how to safely disconnect themselves from the machine during an emergency, like a fire or power outage. Researchers tested 620 patients from multiple countries using a checklist. The goal was to see if training helps patient…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 13, 2026 15:59 UTC