Istanbul University

This trial tests whether measuring the spinal canal with ultrasound before surgery can help doctors give the right amount of spinal anesthesia. The study includes men aged 40 and older having prostate surgery. Half receive a dose based on their individual spinal canal size, while…

This trial tests whether personalizing the air pressure used during mechanical ventilation (called PEEP) can better protect brain blood flow and thinking skills after robotic prostate surgery. About 45 adults having robot-assisted prostatectomy will be randomly assigned to either…

This trial tests whether adding whole-body vibration to standard physical therapy improves wrist function and sensation in people recovering from a distal radius fracture treated with a cast. Participants will be randomly assigned to receive either vibration plus rehab or rehab a…

This study tests whether a new electrolytic cleaning method can improve treatment for peri-implantitis, a gum infection around dental implants. About 80 adults will receive either standard surgical cleaning or standard cleaning plus an electric spark treatment. Researchers will m…

This study looks at whether a 12-week Mediterranean diet can lower oxidative stress and improve blood sugar control in girls aged 10-18 with type 1 diabetes who have high HbA1c levels. Researchers will measure changes in blood markers and glucose levels. The goal is to see if thi…

Researchers at Istanbul University are testing whether a structured home exercise program paired with self-management education helps adults with Parkinson disease improve balance, walking, hand dexterity, and quality of life. The trial enrolls 55 people aged 45 to 80 who have ha…

This study tests two simple, non-drug methods to help women feel less anxious and in pain during mammograms and breast ultrasounds. One group will squeeze a stress ball before and during the procedure, another will receive calming words and gentle touch, and a third will get stan…

This study tests whether adding whole-body vibration (standing on a vibrating platform) to a home exercise program helps people with Parkinson's disease improve balance, mobility, and fall risk more than exercise alone. About 68 adults aged 50-75 with mild to moderate Parkinson's…

This study compares three different wrist splint positions (flexed, neutral, and extended) worn at night for eight weeks in 108 adults with mild to moderate carpal tunnel syndrome. All participants also receive education and exercises. The goal is to see which position best reduc…

This study tests whether a wearable activity tracker and guided exercise app can reduce fatigue and improve quality of life in teens aged 13-18 who are undergoing cancer treatment. Half of the 50 participants will follow an 8-week structured exercise program using the wearable, w…

This study compares a single-shade flowable composite resin to a multi-shade composite for filling cavities in back teeth. Thirty adults with at least four cavities will receive both types of fillings and be followed for five years. Researchers will check how well the fillings ma…

Researchers at Istanbul University are studying how lung function, aerobic and anaerobic fitness, and trunk muscle strength relate in professional male wrestlers. About 28 wrestlers aged 18 to 35 will undergo breathing tests, a treadmill exercise test, a cycling power test, and t…

This study tests whether an animated video or a training booklet can improve breast cancer and screening knowledge among Palestinian women aged 40-69. Participants are randomly assigned to receive one of the two educational tools. The goal is to see which method better boosts und…

This study looks at 128 adults having gallbladder surgery to see if using a low-flow (more eco-friendly) versus normal-flow sevoflurane anesthesia changes heart electrical signals linked to dangerous rhythms. Researchers will measure these signals before, during, and after surger…

This study looks at whether children with juvenile idiopathic arthritis (JIA) have scoliosis (a curved spine) and how it affects their daily life, posture, and arthritis activity. Researchers will check 200 children aged 8-18 using X-rays and health surveys. The goal is to unders…

This study tests whether a new monitoring tool called Oxygen Reserve Index (ORi) can detect low oxygen levels earlier than the standard method during throat surgery. Eighty adults having elective endolaryngeal surgery will be randomly assigned to ORi or standard monitoring. The g…