Istanbul University

This study tests whether playing virtual reality games can improve arm and hand function in people with Duchenne muscular dystrophy (DMD). 36 participants will either do standard physical therapy or the same therapy plus VR exercises using a Meta Quest 3 headset. The goal is to s…

This study tests whether adding a low dose of losartan, a blood pressure medicine, to a standard exercise program can improve pain and movement in people with frozen shoulder. Thirty-three adults with frozen shoulder will be randomly assigned to either exercise alone or exercise …

This study tests whether injecting a sugar-water solution (dextrose prolotherapy) into the tailbone area can reduce pain and improve daily function in people with long-term coccydynia (tailbone pain). The trial will include 40 adults who have had tailbone pain for over 6 months a…

This study tests whether hyaluronic acid injections into the knee can reduce pain and inflammation in people with knee osteoarthritis. Researchers will measure changes in inflammatory markers and ask 50 participants aged 45-75 about their pain and quality of life. The goal is to …

This study tests whether fun, child-friendly core exercises can improve balance and daily movement in children aged 6-12 with spastic cerebral palsy. 54 children will either do these special exercises or a standard home program for 8 weeks. The goal is to see if the fun exercises…

This study tests whether adding simple mental tasks (like counting or word games) to standard shoulder exercises can reduce pain and improve function better than exercise alone. About 46 adults with chronic shoulder pain will do either dual-task or standard exercises twice a week…

This study tests a new exercise program for people with ongoing shoulder pain from rotator cuff problems. Instead of just doing standard shoulder exercises, participants will also perform tasks that shift their attention away from the shoulder. The goal is to see if this approach…

This study looks at whether placing thin covers (veneers) on the front teeth of children with a rare inherited enamel problem (amelogenesis imperfecta) can improve their quality of life. Twenty children aged 11 to 14 will receive veneers and be assessed before and one month after…

This study looks at whether a custom mouthguard (occlusal splint) can reduce pain and muscle tightness in the jaw, head, and neck for people with bruxism (teeth grinding) and myofascial pain. About 40 adults will be split into two groups: one gets the mouthguard right away, the o…

This study looks at how smoking cigarettes can change the shape and thickness of the cornea, the clear front part of the eye. Researchers will measure the eyes of 90 healthy adults, including smokers and non-smokers, before and after 10 minutes of smoke exposure. The goal is to s…

This study looks at how well the diaphragm (the main breathing muscle) works in children aged 1-12 with obstructive sleep apnea who are having surgery. Researchers will use ultrasound to measure diaphragm movement and thickness before and after the operation. They will compare th…

This study is developing a computer model that uses machine learning to predict how the spine curve (Cobb angle) in teens with scoliosis will change after 12 weeks of core exercises. Researchers will collect data from 30 participants aged 10-18 with mild to moderate curves. The g…

This study looks at children who had surgery 1-2 years ago to see if using a special brain monitor (pEEG) during anesthesia helped them have fewer behavior problems afterward. Researchers will compare kids who got pEEG-guided anesthesia with those who got standard care. The goal …

This study compares two computer-controlled ways of giving anesthesia during spine surgery. The goal is to see which method keeps heart rate and blood pressure more stable. About 50 adults having spine surgery will take part. The results may help doctors choose the best anesthesi…

This study looks at four different hip surgeries (Salter, Dega, San Diego, and Pemberton) in children aged 2 to 18 with hip dysplasia. Researchers create 3D computer models from MRI scans to see how each surgery changes the shape and volume of the hip socket. The goal is to under…