Hidden spine problem in kids with arthritis under spotlight
NCT ID NCT07433894
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether children with juvenile idiopathic arthritis (JIA) have scoliosis (a curved spine) and how it affects their daily life, posture, and arthritis activity. Researchers will check 200 children aged 8-18 using X-rays and health surveys. The goal is to understand how often scoliosis occurs in these children and its impact, which is not routinely assessed.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 200 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consists of children and adolescents aged 8-18 years diagnosed with juvenile idiopathic arthritis (JIA) according to ILAR criteria and followed up at a tertiary pediatric rheumatology center. Participants will be recruited consecutively during routine outpatient visits. The aim of the study is to evaluate the prevalence and severity of scoliosis, as defined by Cobb angle measurements on physical examination and, if necessary, standing spinal radiographs, and to examine its relationship with clinical and functional parameters. Both patients with and without scoliosis will be included in the study.
- Ages
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8 to 18 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria * Age between 8 and 18 years at the time of enrollment * Diagnosis of juvenile idiopathic arthritis (JIA) according to ILAR criteria * Written informed consent obtained from parent/legal guardian and assent from the child/adolescent, when appropriate Exclusion Criteria * Known scoliosis due to non-JIA causes (e.g., congenital vertebral anomalies, neuromuscular disorders, or syndromic scoliosis) * History of prior spinal surgery or current brace treatment for scoliosis * History of significant spinal trauma or spinal infection/tumor affecting spinal alignment * Presence of coexisting chronic conditions that significantly affect posture, gait, or functional testing (e.g., severe neurologic impairment) and may confound assessments * Inability to undergo required assessments (e.g., inability to stand for radiographs or complete functional measures)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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