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Night splints for carpal tunnel: which angle works best?

NCT ID NCT07458152

Symptom relief Sponsor: Istanbul University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares three different wrist splint positions (flexed, neutral, and extended) worn at night for eight weeks in 108 adults with mild to moderate carpal tunnel syndrome. All participants also receive education and exercises. The goal is to see which position best reduces pain, numbness, and improves nerve function. Results will help guide conservative treatment for this common condition.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
wrist splint
What this could lead to
If successful, this could identify the best wrist position for splinting to relieve carpal tunnel symptoms without surgery.
What could go wrong
This is a small, early-stage trial with no blinding of participants. Results may not apply to severe cases or long-term use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 108 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

Jan 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of mild to moderate carpal tunnel syndrome confirmed by electrophysiological studies performed within the last year. * Clinical findings consistent with carpal tunnel syndrome. * Age between 18 and 65 years. Exclusion Criteria: * \<18 years or \>65 years * Thenar atrophy * Surgery history for CTS * Steroid injection for CTS * Physical treatment for CTS in the last 6 months * Cervical radiculopathy * Tenosynovitis * Peripheral polyneuropathy * Another compressive neuropathy in the ipsilateral upper extremity * History of trauma/fracture to the hand-wrist region * Pregnancy * Metabolic disease * Rheumatic/autoimmune disease * Kidney failure

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Conditions

The condition(s) this trial relates to.

carpal tunnel syndrome median nerve neuropathy nerve compression syndrome peripheral nervous system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Carpal tunnel syndrome (CTS) Median nerve entrapment Peripheral neuropathies

How to take part

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  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.