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Scalpel vs sound waves: two carpal tunnel surgeries go head to head

NCT ID NCT07814547

Symptom relief Sponsor: AUVA General Trauma Hospital Salzburg Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 11, 2026 · Last updated Sep 11, 2026

Summary

Carpal tunnel syndrome happens when a nerve in the wrist gets squeezed, causing pain, numbness, and weakness in the hand. Open surgery has long been the standard fix, but a newer minimally invasive method uses ultrasound to guide the release through a much smaller opening. This study follows 200 adults who need surgery, comparing how much their symptoms and hand function improve over a year. Researchers track pain, grip, and quality of life to see whether the ultrasound-guided approach holds up against traditional open surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Two surgical approaches for carpal tunnel syndrome: traditional open release and minimally invasive ultrasound-guided release
What this could lead to
If the ultrasound-guided approach works as well as open surgery, it could offer people with carpal tunnel syndrome less postoperative pain and a faster return to normal hand use.
What could go wrong
This is an observational study, not a randomized trial, so differences between the two groups may reflect patient or center characteristics rather than the procedures themselves. The minimally invasive technique also requires specific ultrasound skills, and results may not apply everywhere.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Jul 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants will be recruited during routine clinical consultations at the outpatient clinics of the participating centers. Patients fulfilling the inclusion criteria will be informed about the study by their treating physicians. Participation is voluntary and does not affect the quality of medical care.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Electrophysiologically verified Carpal Tunnel Syndrome by EMG/nerve conduction studies, with the examination not older than 6 months at the time of inclusion. * Previous documented and exhausted conservative treatment * Existing indication for surgery that has been discussed with the patient and the patient's explicit wish to undergo surgical treatment. * Ability to provide informed consent and written informed consent * Age ≥18 years. Exclusion Criteria: * Previous surgery at the affected location or revision procedures. * Pre-existing nerve lesions of the upper extremity, including traumatic transections or proximal injuries. * Manifest polyneuropathy. * Foreseeable loss to follow-up, for example inability to contact the participant or insufficient compliance, before the critical 3-month follow-up. * Age under 18 years.

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Conditions

The condition(s) this trial relates to.

carpal tunnel syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Carpal tunnel syndrome (CTS)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • AUVA General Trauma Hospital Salzburg

    RECRUITING

    Salzburg, 5010, Austria

  • University Institute of Radiology, Paracelsus Medical Private University Salzburg

    RECRUITING

    Salzburg, 5020, Austria

More trials for these conditions

Other studies related to the condition(s) this trial covers.