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Sugar water shots ease shoulder pain in new study

NCT ID NCT04805242

Symptom relief Sponsor: Istanbul University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This study tested whether injecting a sugar-water solution (dextrose prolotherapy) into the shoulder can reduce pain and improve function in people with chronic rotator cuff disease. Sixty adults aged 30 to 65 with shoulder pain lasting more than three months took part. The treatment aims to stimulate healing and provide symptom relief without surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Mar 2021

Finished

Nov 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 30 and 65 years * Shoulder pain lasting longer than 3 months * Resistance to conservative treatment for at least 3 months * Diagnosis of rotator cuff disease confirmed by clinical examination and magnetic resonance imaging (MRI) Exclusion Criteria: * Presence of rheumatic disease or other systemic inflammatory diseases * Uncontrolled diabetes mellitus * Local or systemic infection * History of previous shoulder surgery * Bleeding tendency (acquired or hereditary) or use of anticoagulant therapy with INR \>2 * Shoulder injection within the previous 8 weeks * Allergy to local anesthetics * Passive shoulder abduction \<100° or external rotation \<25° * Rotator cuff calcification with diameter \>0.8 cm detected on radiography or ultrasonography * Full-thickness rotator cuff tear * Presence of severe comorbid disease

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Conditions

The condition(s) this trial relates to.

rotator cuff syndrome Shoulder Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Rotator cuff disease

Contacts and locations

Locations

  • Istanbul University Istanbul Faculty of Medicine, Department of Physical Medicine and Rehabilitation

    Istanbul, Fatih, 34034, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.