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Umbilical cord stem cells tested for shoulder injury

NCT ID NCT07605559

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether injecting stem cells from umbilical cords can help heal partial rotator cuff tears in the shoulder. Thirty-eight adults with ongoing shoulder pain will receive either a high or medium dose of stem cells or a placebo. The main goal is to see if the tear shrinks on MRI scans.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
umbilical cord-derived mesenchymal stem cells
What this could lead to
If it works, this could offer a non-surgical way to heal partial rotator cuff tears and reduce shoulder pain.
What could go wrong
This is a small, early-stage trial with only 38 participants. The stem cells may not repair the tear, and there is a risk of injection-related side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 38 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

19 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 19 years or older * Shoulder pain lasting for at least 3 months * A pain visual analogue scale (VAS) score of 4 or greater * Inadequate response to sufficient conservative treatment for at least 3 months, such as medication, injection therapy, physical therapy, or exercise therapy * Partial-thickness rotator cuff tear confirmed by ultrasonography or magnetic resonance imaging (MRI) * No restrictions on participation in clinical trial procedures, including hospitalization Exclusion Criteria: * Receipt of subacromial injection therapy in the affected shoulder within the past 3 months * History of rotator cuff surgery on the affected shoulder within the past 6 months * Previous treatment with a stem cell therapy for the shoulder * Presence of any of the following shoulder conditions: full-thickness rotator cuff tear, obvious isolated acromioclavicular joint arthropathy, or a clear history of trauma to the shoulder joint within the past 3 months * Radiologic findings suggestive of or consistent with any of the following: malignancy, severe glenohumeral osteoarthritis, bony abnormalities causing narrowing of the subacromial space, or clear evidence of acute traumatic rotator cuff injury * Presence of symptomatic cervical spine disease * Patients with polyarthritis, infectious arthritis, rheumatoid arthritis, or fibromyalgia * Clinical trial subjects with neurological deficits * Pregnant or breastfeeding women * Unwillingness to use an effective method of contraception during participation in the clinical trial * Presence of any serious disease that may affect participation in this clinical trial, including cardiovascular, renal, hepatic, endocrine, or neoplastic disease * Inability to understand the questions used to assess the subject's condition, including the visual analogue scale (VAS), or communication difficulties due to psychiatric illness * Unwillingness to participate in the clinical trial or difficulty in complying with follow-up visits according to the study schedule * Participation in another clinical trial within 3 months prior to enrollment in this clinical trial * Any other condition that, in the opinion of the investigator, makes the subject unsuitable for participation in this clinical trial

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Asan Medical Center

    Seoul, Seoul, 05505, South Korea

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