Institut Curie

This early-phase study tested the drug olaparib together with radiation therapy in 24 women with a hard-to-treat type of breast cancer called triple-negative breast cancer (TNBC). The main goal was to find the safest dose of olaparib when given with radiation and to check for sid…

This study tested a combination of three drugs (pomalidomide, cyclophosphamide, and dexamethasone) in 100 adults with multiple myeloma whose cancer returned after initial treatment. Participants had previously received standard therapies including bortezomib and lenalidomide. The…

This study tested two different ways of giving radiation to children and teens (ages 4–21) with a common brain tumor called medulloblastoma that hasn't spread. The goal was to see if giving smaller, more frequent doses (hyperfractionated) works better than the standard once-daily…

This study tested whether adding a special PET scan (FAZA-PET) to standard imaging can improve the effectiveness of proton therapy for chordoma, a rare bone tumor. The goal was to better target radiation-resistant cells and improve local tumor control. 64 adults with chordoma of …

This study tested whether injecting a local anesthetic (ropivacaine) during breast cancer surgery could prevent chronic pain that sometimes lasts for months after the operation. 260 women having breast-conserving surgery or mastectomy took part. The researchers compared pain leve…

This study looked at whether a special day hospital that combines cancer care with palliative support can improve the quality of life for adults with advanced cancer. 144 patients took part. The goal was to see if this approach helps patients feel better and live well for as long…

This study tested whether giving a booklet-question list to people with advanced cancer (or their families) helps them ask more questions during a palliative care visit. 121 participants were randomly assigned to receive the booklet or not. The goal was to see if the booklet enco…

This study tested whether a 3D ultrasound technique called shear wave elastography can accurately predict how breast tumors respond to chemotherapy before surgery. Researchers measured tumor stiffness at several points during treatment in 140 women with locally advanced breast ca…

This study looked at how women feel after getting a personalized estimate of their breast cancer risk. Researchers used a special model to calculate each woman's risk and then asked them questions about their worries and understanding. The goal was to see if this detailed risk in…

This study tested whether breast cancer gives off a unique smell that can be captured by a special sensor. Researchers collected scent samples from the hands and tumors of 35 women before and after breast cancer surgery. The goal was to see if these odors could one day help detec…

This study tested whether choosing cancer drugs based on the genetic profile of a patient's tumor works better than standard chemotherapy for people with advanced solid tumors that no longer respond to usual treatments. Over 700 participants had a biopsy to identify genetic chang…

This study looked at whether measuring circulating tumor cells (CTCs) in the blood can help doctors decide when to switch chemotherapy for women with metastatic breast cancer. 265 women who had already tried two chemotherapy treatments took part. The goal was to see if using CTC …